loading...| Preferred Name |
Platelet-Derived Growth Factor Subunit B |
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| Synonyms |
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| Definitions |
Platelet-derived growth factor subunit B (241 aa, ~27 kDa) is encoded by the human PDGFB gene. This protein is involved in the regulation of embryonic development, cell proliferation, cell migration, cell survival and chemotaxis. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C20449 |
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| code |
C20449 |
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| Contributing_Source |
CTRP |
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| definition |
Platelet-derived growth factor subunit B (241 aa, ~27 kDa) is encoded by the human PDGFB gene. This protein is involved in the regulation of embryonic development, cell proliferation, cell migration, cell survival and chemotaxis. |
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| DesignNote |
Platelet-derived growth factor subunit B can exist as either antiparallel disulfide-linked homodimers or as heterodimers with platelet-derived growth factor subunit A. A-A, B-B, and A-B, dimers can bind to PDGF receptors and elicit a variety of cellular responses. |
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| Display_Name |
Platelet-Derived Growth Factor Subunit B |
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| in_subset |
http://purl.obolibrary.org/obo/NCIT_C116977 |
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| label |
Platelet-Derived Growth Factor Subunit B |
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| Legacy Concept Name |
Platelet_Derived_Growth_Factor_Beta_Chain |
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| OMIM_Number |
190040 |
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| Preferred_Name |
Platelet-Derived Growth Factor Subunit B |
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| prefixIRI |
NCIT:C20449 |
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| prefLabel |
Platelet-Derived Growth Factor Subunit B |
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| Semantic_Type |
Amino Acid, Peptide, or Protein |
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| Swiss_Prot |
P01127 |
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| UMLS_CUI |
C0072480 |
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| subClassOf |