Preferred Name

Prazosin Hydrochloride

Synonyms
Definitions

A synthetic piperazine derivative with hypotensive antiadrenergic properties, Prazosin Hydrochloride reduces peripheral resistance and relaxes vascular smooth muscles as a selective adrenergic alpha-1 antagonist by a mechanism not completely known. It is used in the treatment of heart failure, hypertension, pheochromocytoma, Raynaud's syndrome, prostatic hypertrophy, and urinary retention. (NCI04)

ID

http://purl.obolibrary.org/obo/NCIT_C1507

CAS_Registry

19237-84-4

CHEBI_ID

CHEBI:8365

Chemical_Formula

C19H21N5O4.HCl

code

C1507

Contributing_Source

FDA

definition

A synthetic piperazine derivative with hypotensive antiadrenergic properties, Prazosin Hydrochloride reduces peripheral resistance and relaxes vascular smooth muscles as a selective adrenergic alpha-1 antagonist by a mechanism not completely known. It is used in the treatment of heart failure, hypertension, pheochromocytoma, Raynaud's syndrome, prostatic hypertrophy, and urinary retention. (NCI04)

FDA_UNII_Code

X0Z7454B90

Has_Free_Acid_Or_Base_Form

http://purl.obolibrary.org/obo/NCIT_C767

in_subset

http://purl.obolibrary.org/obo/NCIT_C63923

label

Prazosin Hydrochloride

Legacy Concept Name

Prazosin_Hydrochloride

NSC Number

292810

Preferred_Name

Prazosin Hydrochloride

prefixIRI

NCIT:C1507

prefLabel

Prazosin Hydrochloride

Semantic_Type

Organic Chemical

Pharmacologic Substance

UMLS_CUI

C0700578

subClassOf

http://purl.obolibrary.org/obo/NCIT_C29713

http://purl.obolibrary.org/obo/NCIT_C270

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