loading...| Preferred Name |
Fluoroquinolone Antibiotic |
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| Synonyms |
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| Definitions |
Any quinolone antibiotic with a fluorine (F) atom attached to the quinolone structure, with broad-spectrum antibacterial activity. Fluoroquinolones diffuse through the bacterial cell wall and act by inhibiting bacterial topoisomerase II, DNA gyrase and/or bacterial topoisomerase IV, which are enzymes involved in bacterial DNA replication. This prevents DNA replication and leads to a blockage of bacterial cell proliferation. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C126712 |
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| code |
C126712 |
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| Contributing_Source |
CTRP |
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| definition |
Any quinolone antibiotic with a fluorine (F) atom attached to the quinolone structure, with broad-spectrum antibacterial activity. Fluoroquinolones diffuse through the bacterial cell wall and act by inhibiting bacterial topoisomerase II, DNA gyrase and/or bacterial topoisomerase IV, which are enzymes involved in bacterial DNA replication. This prevents DNA replication and leads to a blockage of bacterial cell proliferation. |
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| Display_Name |
Fluoroquinolone Antibiotic |
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| in_subset | ||
| label |
Fluoroquinolone Antibiotic |
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| Preferred_Name |
Fluoroquinolone Antibiotic |
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| prefixIRI |
NCIT:C126712 |
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| prefLabel |
Fluoroquinolone Antibiotic |
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| Semantic_Type |
Chemical Viewed Functionally |
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| UMLS_CUI |
C0949665 |
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| subClassOf |