loading...| Preferred Name |
Fosfestrol |
|
| Synonyms |
|
|
| Definitions |
The diphosphate ester of a synthetic, nonsteroidal form of estrogen. A well-known teratogen and carcinogen, diethylstilbestrol inhibits the hypothalamic-pituitary-gonadal axis, thereby blocking the testicular synthesis of testosterone, lowering plasma testosterone, and inducing a chemical castration. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C1105 |
|
| Accepted_Therapeutic_Use_For |
Advanced Prostate Cancer; palliative treatment of breast cancer in postmenopausal women and in men |
|
| CAS_Registry |
522-40-7 |
|
| CHEBI_ID |
CHEBI:4532 |
|
| Chemical_Formula |
C18H22O8P2 |
|
| code |
C1105 |
|
| Contributing_Source |
FDA |
|
| definition |
The diphosphate ester of a synthetic, nonsteroidal form of estrogen. A well-known teratogen and carcinogen, diethylstilbestrol inhibits the hypothalamic-pituitary-gonadal axis, thereby blocking the testicular synthesis of testosterone, lowering plasma testosterone, and inducing a chemical castration. |
|
| FDA_UNII_Code |
A0E0NMA80F |
|
| in_subset | ||
| label |
Fosfestrol |
|
| Legacy Concept Name |
Diethylstilbestrol_Diphosphate |
|
| NCI_Drug_Dictionary_ID |
39308 |
|
| NSC Number |
10481 |
|
| PDQ_Closed_Trial_Search_ID |
39308 |
|
| PDQ_Open_Trial_Search_ID |
39308 |
|
| Preferred_Name |
Fosfestrol |
|
| prefixIRI |
NCIT:C1105 |
|
| prefLabel |
Fosfestrol |
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
| UMLS_CUI |
C0060692 |
|
| subClassOf |