loading...| Preferred Name |
acrivastine |
|
| Synonyms |
(2E)-3-{6-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridin-2-yl}acrylic acid (E)-6-((E)-3-(1-Pyrrolidinyl)-1-p-tolylpropenyl)-2-pyridineacrylic acid acrivastinum acrivastina acrivastine BW 825C BW A825C |
|
| Definitions |
A member of the class of pyridines that is (pyridin-2-yl)acrylic acid substituted at position 6 by a [(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl group. It is a non-sedating antihistamine used for treatment of hayfever, urticaria, and rhinitis. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_83168 |
|
| charge |
0 |
|
| database_cross_reference |
PMID:2574054 PMID:1355745 Wikipedia:Acrivastine PMID:1715267 Drug_Central:82 PMID:8630717 PMID:6149965 PMID:24813276 PMID:2570003 PMID:2906886 PMID:2570001 PMID:2901993 PMID:2859204 PMID:2569998 PMID:7860231 Reaxys:6739893 PMID:2570000 PMID:23047471 PMID:1970907 PMID:22936420 CAS:87848-99-5 PMID:18968530 PMID:2569999 KEGG:D02760 |
|
| definition |
A member of the class of pyridines that is (pyridin-2-yl)acrylic acid substituted at position 6 by a [(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl group. It is a non-sedating antihistamine used for treatment of hayfever, urticaria, and rhinitis. |
|
| formula |
C22H24N2O2 |
|
| has_exact_synonym |
(2E)-3-{6-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridin-2-yl}acrylic acid |
|
| has_obo_namespace |
chebi_ontology |
|
| has_related_synonym |
(E)-6-((E)-3-(1-Pyrrolidinyl)-1-p-tolylpropenyl)-2-pyridineacrylic acid acrivastinum acrivastina acrivastine BW 825C BW A825C |
|
| id |
CHEBI:83168 |
|
| in_subset | ||
| inchi |
InChI=1S/C22H24N2O2/c1-17-7-9-18(10-8-17)20(13-16-24-14-2-3-15-24)21-6-4-5-19(23-21)11-12-22(25)26/h4-13H,2-3,14-16H2,1H3,(H,25,26)/b12-11+,20-13+ |
|
| inchikey |
PWACSDKDOHSSQD-IUTFFREVSA-N |
|
| label |
acrivastine |
|
| mass |
348.43820 |
|
| monoisotopicmass |
348.18378 |
|
| notation |
CHEBI:83168 |
|
| prefLabel |
acrivastine |
|
| RO_0000087 | ||
| smiles |
Cc1ccc(cc1)C(=C/CN1CCCC1)\c1cccc(\C=C\C(O)=O)n1 |
|
| subClassOf |
http://purl.obolibrary.org/obo/CHEBI_79020 http://purl.obolibrary.org/obo/CHEBI_78840 |