loading...| Preferred Name |
trimethoprim |
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| Synonyms |
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| Definitions |
Trimethoprim is a synthetic 5-(3,4,5- trimethoxybenzyl) pyrimidine inhibitor of dihydrofolate reductase, inhibiting synthesis of tetrahydrofolic acid. Tetrahydrofolic acid is an essential precursor in the de novo synthesis of the DNA nucleotide thymidine. Trimethoprim is a bacteriostatic antibiotic mainly used in the prophylaxis and treatment of urinary tract infections in combination with sulfamethoxazole, a sulfonamide antibiotic. |
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| ID |
http://purl.obolibrary.org/obo/ARO_3000188 |
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| database_cross_reference |
pubchem.compound:5578 |
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| definition |
Trimethoprim is a synthetic 5-(3,4,5- trimethoxybenzyl) pyrimidine inhibitor of dihydrofolate reductase, inhibiting synthesis of tetrahydrofolic acid. Tetrahydrofolic acid is an essential precursor in the de novo synthesis of the DNA nucleotide thymidine. Trimethoprim is a bacteriostatic antibiotic mainly used in the prophylaxis and treatment of urinary tract infections in combination with sulfamethoxazole, a sulfonamide antibiotic. |
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| has_obo_namespace |
antibiotic_resistance |
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| id |
ARO:3000188 |
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| label |
trimethoprim |
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| notation |
ARO:3000188 |
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| prefLabel |
trimethoprim |
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| subClassOf |