loading...| Preferred Name |
glycopeptide antibiotic |
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| Synonyms |
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| Definitions |
Glycopeptide antibiotics are natural products produced non-ribosomally by Actinomycetales bacteria. With the exception of bleomycins, they act by binding the terminal D-Ala-D-Ala in peptidoglycan precursors of the growing bacterial cell wall and are generally active against Gram-positive bacteria. This inhibits transglycosylation leading to cell death due to osmotic stress. |
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| ID |
http://purl.obolibrary.org/obo/ARO_3000081 |
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| definition |
Glycopeptide antibiotics are natural products produced non-ribosomally by Actinomycetales bacteria. With the exception of bleomycins, they act by binding the terminal D-Ala-D-Ala in peptidoglycan precursors of the growing bacterial cell wall and are generally active against Gram-positive bacteria. This inhibits transglycosylation leading to cell death due to osmotic stress. |
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| has_obo_namespace |
antibiotic_resistance |
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| id |
ARO:3000081 |
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| label |
glycopeptide antibiotic |
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| notation |
ARO:3000081 |
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| prefLabel |
glycopeptide antibiotic |
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| subClassOf |