Antibiotic Resistance Ontology

Last uploaded: October 23, 2019
Preferred Name

glycopeptide antibiotic

Definitions

Glycopeptide antibiotics are natural products produced non-ribosomally by Actinomycetales bacteria. With the exception of bleomycins, they act by binding the terminal D-Ala-D-Ala in peptidoglycan precursors of the growing bacterial cell wall and are generally active against Gram-positive bacteria. This inhibits transglycosylation leading to cell death due to osmotic stress.

ID

http://purl.obolibrary.org/obo/ARO_3000081

definition

Glycopeptide antibiotics are natural products produced non-ribosomally by Actinomycetales bacteria. With the exception of bleomycins, they act by binding the terminal D-Ala-D-Ala in peptidoglycan precursors of the growing bacterial cell wall and are generally active against Gram-positive bacteria. This inhibits transglycosylation leading to cell death due to osmotic stress.

has_obo_namespace

antibiotic_resistance

id

ARO:3000081

label

glycopeptide antibiotic

notation

ARO:3000081

prefLabel

glycopeptide antibiotic

subClassOf

http://purl.obolibrary.org/obo/ARO_1000003

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http://purl.obolibrary.org/obo/HIO_0000281 HIO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/414355008 SNOMEDCT LOOM
https://bioportal.bioontology.org/ontologies/FTDM.owl#glycopeptide_antibiotic FASTO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0162724 OCHV LOOM
http://purl.obolibrary.org/obo/CHEBI_24395 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_24395 DRON LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61101 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61101 NCIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61101 NCIT LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000468927 PDQ LOOM