Antibiotic Resistance Ontology

Last uploaded: March 20, 2024
Preferred Name

gentamicin

Synonyms

Gentamicins

Garamycin

Gentavet

Gentamicinum

Cidomycin

Gentacycol

Definitions

Gentamicin is a commonly used aminoglycoside antibiotic derived from members of the Micromonospora genus of bacteria. It acts by binding the 30S ribosomal subunit, thus inhibiting protein synthesis. Gentamicin is typically used to treat Gram-negative infections of the repiratory and urinary tract, as well as infections of the bone and soft tissue. It also exhibits considerable nephrotoxicity and ototoxicity. Gentamicin is administered as a mixture of gentamicin type C (which makes about around 80% of the complex) and types A, B, and X (distributed in the remaining 20% of the complex).

ID

http://purl.obolibrary.org/obo/ARO_3007382

database_cross_reference

pubchem.compound:3467

definition

Gentamicin is a commonly used aminoglycoside antibiotic derived from members of the Micromonospora genus of bacteria. It acts by binding the 30S ribosomal subunit, thus inhibiting protein synthesis. Gentamicin is typically used to treat Gram-negative infections of the repiratory and urinary tract, as well as infections of the bone and soft tissue. It also exhibits considerable nephrotoxicity and ototoxicity. Gentamicin is administered as a mixture of gentamicin type C (which makes about around 80% of the complex) and types A, B, and X (distributed in the remaining 20% of the complex).

has_exact_synonym

Gentamicins

Garamycin

Gentavet

Gentamicinum

Cidomycin

Gentacycol

has_obo_namespace

antibiotic_resistance

id

ARO:3007382

label

gentamicin

notation

ARO:3007382

prefLabel

gentamicin

subClassOf

http://purl.obolibrary.org/obo/ARO_3000707

http://purl.obolibrary.org/obo/ARO_0000016

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http://purl.obolibrary.org/obo/CHEBI_17833 HOIP LOOM
http://purl.bioontology.org/ontology/CSP/0191-7691 CRISP LOOM
http://purl.bioontology.org/ontology/ATC/S03AA06 ATC LOOM
http://purl.bioontology.org/ontology/ATC/J01GB03 ATC LOOM
http://purl.obolibrary.org/obo/DRON_00730841 PDRO LOOM
http://purl.bioontology.org/ontology/VANDF/4019765 VANDF LOOM
http://www.phoc.org.cn/pmo/class/PMO_00025743 PMAPP-PMO LOOM
http://www.co-ode.org/ontologies/galen#Gentamicin GALEN LOOM
http://purl.bioontology.org/ontology/RXNORM/1596450 RXNORM LOOM
http://purl.bioontology.org/ontology/ATC/S02AA14 ATC LOOM
http://purl.bioontology.org/ontology/CPT/80170 CPT LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0017436 OCHV LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C519 NCIT LOOM
http://purl.obolibrary.org/obo/NCIT_C519 BERO LOOM
http://purl.obolibrary.org/obo/NCIT_C519 SCDO LOOM
http://purl.obolibrary.org/obo/dinto_DB00798 DINTO LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000039250 PDQ LOOM
http://purl.obolibrary.org/obo/CHEBI_17833 TXPO LOOM
http://purl.jp/bio/4/id/200906052661342087 IOBC LOOM
http://purl.bioontology.org/ontology/SNMI/C-52530 SNMI LOOM
https://go.drugbank.com/drugs/DB00798 MDM LOOM
http://purl.bioontology.org/ontology/LNC/MTHU004260 LOINC LOOM
http://purl.bioontology.org/ontology/ATC/D06AX07 ATC LOOM
http://purl.bioontology.org/ontology/NDDF/004898 NDDF LOOM
http://id.nlm.nih.gov/mesh/D005839 MDM LOOM
http://purl.bioontology.org/ontology/LNC/LP15747-6 LOINC LOOM
http://www.drugbank.ca/drugs/DB00798 FTC LOOM
http://purl.obolibrary.org/obo/HIO_0000278 HIO LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147856 NDFRT LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387321007 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/ATC/S01AA11 ATC LOOM