loading...| Preferred Name |
streptogramin B antibiotic |
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| Synonyms |
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| Definitions |
Streptogramin B antibiotics are are cyclic hepta- or hexa-depsipeptides. Type B streptogramins block the peptide exit tunnel of the 50S bacterial ribosome. The general composition of group B streptogramins is 3-hydroxypicolinic acid-L-Thr-D-aminobutyric acid (or D-Ala)-L-Pro-L-Phe (or 4-N-,N-(dimethylamino)-L-Phe)-X-L-phenylglycine. Used alone, streptogramin B antibiotics are bacteriostatic, but is bactericidal when used with streptogramin A antibiotics. |
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| ID |
http://purl.obolibrary.org/obo/ARO_0000050 |
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| definition |
Streptogramin B antibiotics are are cyclic hepta- or hexa-depsipeptides. Type B streptogramins block the peptide exit tunnel of the 50S bacterial ribosome. The general composition of group B streptogramins is 3-hydroxypicolinic acid-L-Thr-D-aminobutyric acid (or D-Ala)-L-Pro-L-Phe (or 4-N-,N-(dimethylamino)-L-Phe)-X-L-phenylglycine. Used alone, streptogramin B antibiotics are bacteriostatic, but is bactericidal when used with streptogramin A antibiotics. |
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| has_obo_namespace |
antibiotic_resistance |
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| id |
ARO:0000050 |
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| label |
streptogramin B antibiotic |
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| notation |
ARO:0000050 |
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| prefLabel |
streptogramin B antibiotic |
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| subClassOf |