Preferred Name |
cephamycin |
|
Synonyms |
|
|
Definitions |
Cephamycins are a group of beta-lactam antibiotics, very similar to cephalosporins. Together with cephalosporins, they form a sub-group of antibiotics known as cephems. Cephamycins are bactericidal, and act by inhibiting the synthesis of the peptidoglycan layer of bacterial cell walls. The peptidoglycan layer is important for cell wall structural integrity, especially in Gram-positive organisms. The 7-alpha-methoxy group increases resistance to beta-lactamases. |
|
ID |
http://purl.obolibrary.org/obo/ARO_0000044 |
|
database_cross_reference |
pubchem.compound:123731 |
|
definition |
Cephamycins are a group of beta-lactam antibiotics, very similar to cephalosporins. Together with cephalosporins, they form a sub-group of antibiotics known as cephems. Cephamycins are bactericidal, and act by inhibiting the synthesis of the peptidoglycan layer of bacterial cell walls. The peptidoglycan layer is important for cell wall structural integrity, especially in Gram-positive organisms. The 7-alpha-methoxy group increases resistance to beta-lactamases. |
|
has_obo_namespace |
antibiotic_resistance |
|
id |
ARO:0000044 |
|
label |
cephamycin |
|
notation |
ARO:0000044 |
|
prefLabel |
cephamycin |
|
subClassOf |