Antibiotic Resistance Ontology

Last uploaded: March 20, 2024
Preferred Name

cephamycin

Synonyms
Definitions

Cephamycins are a group of beta-lactam antibiotics, very similar to cephalosporins. Together with cephalosporins, they form a sub-group of antibiotics known as cephems. Cephamycins are bactericidal, and act by inhibiting the synthesis of the peptidoglycan layer of bacterial cell walls. The peptidoglycan layer is important for cell wall structural integrity, especially in Gram-positive organisms. The 7-alpha-methoxy group increases resistance to beta-lactamases.

ID

http://purl.obolibrary.org/obo/ARO_0000044

database_cross_reference

pubchem.compound:123731

definition

Cephamycins are a group of beta-lactam antibiotics, very similar to cephalosporins. Together with cephalosporins, they form a sub-group of antibiotics known as cephems. Cephamycins are bactericidal, and act by inhibiting the synthesis of the peptidoglycan layer of bacterial cell walls. The peptidoglycan layer is important for cell wall structural integrity, especially in Gram-positive organisms. The 7-alpha-methoxy group increases resistance to beta-lactamases.

has_obo_namespace

antibiotic_resistance

id

ARO:0000044

label

cephamycin

notation

ARO:0000044

prefLabel

cephamycin

subClassOf

http://purl.obolibrary.org/obo/ARO_3000276

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