Preferred Name |
carbapenem |
|
Synonyms |
|
|
Definitions |
Carbapenems are a class of beta-lactam antibiotics with a broad spectrum of antibacterial activity, and have a structure which renders them highly resistant to beta-lactamases. Carbapenem antibiotics are bactericidal, and act by inhibiting the synthesis of the peptidoglycan layer of bacterial cell walls. The peptidoglycan layer is important for cell wall structural integrity, especially in Gram-positive organisms. |
|
ID |
http://purl.obolibrary.org/obo/ARO_0000020 |
|
definition |
Carbapenems are a class of beta-lactam antibiotics with a broad spectrum of antibacterial activity, and have a structure which renders them highly resistant to beta-lactamases. Carbapenem antibiotics are bactericidal, and act by inhibiting the synthesis of the peptidoglycan layer of bacterial cell walls. The peptidoglycan layer is important for cell wall structural integrity, especially in Gram-positive organisms. |
|
has_obo_namespace |
antibiotic_resistance |
|
id |
ARO:0000020 |
|
label |
carbapenem |
|
notation |
ARO:0000020 |
|
prefLabel |
carbapenem |
|
subClassOf |