loading...| Preferred Name |
hypoblast (generic) |
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| Synonyms |
hypoblast future endoderm and mesoderm mesendoderm endomesoderm hypoblastus |
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| Definitions |
Missing definition for term UBERON:0000089. Please replace it using linked reference. |
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| ID |
http://purl.obolibrary.org/obo/UBERON_0000089 |
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| curator note |
this term groups together disparate structures with different relationships. |
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| database_cross_reference |
BTO:0003953 VHOG:0001222 AAO:0010619 EFO:0001930 TAO:0000117 NCIT:C34190 EMAPA:32762 UMLS:C1512561 MAT:0000418 Wikipedia:Hypoblast AAO:0000229 XAO:0003044 ZFA:0000117 MIAA:0000418 FMA:293873 |
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| definition |
Missing definition for term UBERON:0000089. Please replace it using linked reference. |
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| depiction |
http://upload.wikimedia.org/wikipedia/commons/e/e3/Gray21.png |
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| editor note |
TODO - consider relationship to UBERON:0000091 ! bilaminar disc |
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| external_definition |
The inner of the two layers of the blastoderm that forms during gastrulation and give rise to the definitive mesoderm and endoderm. Kimmel et al, 1995.[TAO] A primary germ layer that can give rise to both mesoderm and endoderm.[AAO] |
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| has_exact_synonym |
hypoblast |
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| has_obo_namespace |
uberon |
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| has_related_synonym |
future endoderm and mesoderm mesendoderm endomesoderm hypoblastus |
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| homology_notes |
In mammal and avian, extraembryonic endoderm such as visceral endoderm and hypoblast play essential roles in the embryonic axis formation and germ layer development. These extraembryonic tissues are generally considered to have been created in ancestral amniotes evolved from the Xenopus-type ancestor (reference 1); The endomesoderm secretes as yet unidentified signals that posteriorize the ectoderm, which would otherwise adopt an anterior fate. Our results point to a conserved function at the base of deuterostomes for beta-catenin in germ layer specification and to a causal link in the definition of the posterior part of the embryonic ectoderm by way of activating posteriorizing endomesodermal factors (reference 2).[well established][VHOG] |
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| id |
UBERON:0000089 |
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| in_subset |
http://purl.obolibrary.org/obo/uberon/core#efo_slim http://purl.obolibrary.org/obo/uberon/core#vertebrate_core http://purl.obolibrary.org/obo/uberon/core#early_development |
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| label |
hypoblast (generic) |
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| notation |
UBERON:0000089 |
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| part_of | ||
| prefLabel |
hypoblast (generic) |
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| see also | ||
| term tracker item |
https://sourceforge.net/p/geneontology/ontology-requests/9676/ |
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| treeView | ||
| subClassOf |