loading...| Preferred Name |
glomerular mesangial cell |
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| Synonyms |
intraglomerular mesangial cell |
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| Definitions |
Like smooth muscle, a glomerular mesangial cell is contractile and possesses the filaments actin and myosin. The contractile mechanism is also similar to that of smooth muscle, with Ca2+/calmodulin-activated myosin light-chain kinase instigating myosin-actin cross-bridge cycling. Mesangial cell phagocytosis of apoptotic neutrophils involves a novel CD36-independent, alpha(v)beta3/TSP-mediated mechanism that is uncoupled from chemokine secretion, emphasizing the injury-limiting potential of mesangial cell phagocytosis of apoptotic cells. A mesangial cell located among the glomerular capillaries in a renal corpuscle. |
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| ID |
http://purl.obolibrary.org/obo/CL_1000742 |
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| comment |
Like smooth muscle, a glomerular mesangial cell is contractile and possesses the filaments actin and myosin. The contractile mechanism is also similar to that of smooth muscle, with Ca2+/calmodulin-activated myosin light-chain kinase instigating myosin-actin cross-bridge cycling. Mesangial cell phagocytosis of apoptotic neutrophils involves a novel CD36-independent, alpha(v)beta3/TSP-mediated mechanism that is uncoupled from chemokine secretion, emphasizing the injury-limiting potential of mesangial cell phagocytosis of apoptotic cells. |
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| capable of | ||
| database_cross_reference |
KUPO:0001032 |
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| definition |
A mesangial cell located among the glomerular capillaries in a renal corpuscle. |
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| has_exact_synonym |
intraglomerular mesangial cell |
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| in_subset |
http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas |
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| label |
glomerular mesangial cell |
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| part_of | ||
| prefixIRI |
CL:1000742 |
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| prefLabel |
glomerular mesangial cell |
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| present in taxon | ||
| treeView | ||
| subClassOf |
http://purl.obolibrary.org/obo/CL_1001318 http://purl.obolibrary.org/obo/CL_1000746 |