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Experimental Conditions Ontology
Last uploaded:
December 16, 2024
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| Preferred Name | spironolactone | |
| Synonyms |
7alpha-(acetylsulfanyl)-3-oxo-17alpha-pregn-4-ene-21,17-carbolactone |
|
| Definitions |
Any condition in which the main influencing factor is spironolactone, a potassium-sparing diuretic that competitively inhibits mineralocorticoid receptors in the distal convoluted tubule to promote sodium and water excretion and potassium retention. Spironolactone is indicated to treat a number of conditions including heart failure, edema, hyperaldosteronism, adrenal hyperplasia, hypertension, and nephrotic syndrome. |
|
| ID |
http://purl.obolibrary.org/obo/XCO_0000627 |
|
| created_by |
sjwang
|
|
| creation_date |
2019-07-24T14:33:14Z
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|
| database_cross_reference |
MESH:D013148 CHEBI:9241
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|
| definition |
Any condition in which the main influencing factor is spironolactone, a potassium-sparing diuretic that competitively inhibits mineralocorticoid receptors in the distal convoluted tubule to promote sodium and water excretion and potassium retention. Spironolactone is indicated to treat a number of conditions including heart failure, edema, hyperaldosteronism, adrenal hyperplasia, hypertension, and nephrotic syndrome.
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| has_exact_synonym |
7alpha-(acetylsulfanyl)-3-oxo-17alpha-pregn-4-ene-21,17-carbolactone
|
|
| has_obo_namespace |
experimental_condition_ontology
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|
| id |
XCO:0000627
|
|
| label |
spironolactone
|
|
| notation |
XCO:0000627
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|
| prefLabel |
spironolactone
|
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| treeView | ||
| subClassOf |
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