系统性红斑狼疮

Watad A, Tiosano S, Bragazzi NL, et al. Epilepsy among Systemic Lupus Erythematosus Patients: Insights from a Large Database Analysis. Neuroepidemiology. 2018;50(1-2):1-6. doi:10.1159/000485136 Hopia L, Andersson M, Svenungsson E, Khademi M, Piehl F, Tomson T. Epilepsy in systemic lupus erythematosus: prevalence and risk factors. Eur J Neurol. 2020;27(2):297-307. doi:10.1111/ene.14077

A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.

An autoimmune multi-organ disease typically associated with vasculopathy and autoantibody production. Most patients have antinuclear antibodies (ANA). The presence of anti-dsDNA or anti-Smith antibodies are highly-specific.

Systemic_lupus_erythematosus

disseminated lupus erythematosus LE SYNDROME LE systemic LUPUS ERYTHEMATOSIS (NOS) LUPUS ERYTHEMATOSIS DISSEMINATED Lupus Erythematosus Disseminatus LUPUS ERYTHEMATOSUS SYSTEMIC LUPUS ERYTHEMATOSUS, DISSEMINATED LUPUS ERYTHEMATOSUS, SYSTEMIC LUPUS SYNDROME LUPUS, ERYTHEMATOSUS, SYSTEMIC lupus SLE - Lupus Erythematosus, Systemic SLE - Systemic lupus erythematosus SLE NOS SLE SYNDROME DISSEMINATED LUPUS ERYTHEMATOSIS SYNDROME LUPUS Syst lupus erythematosus SYSTEMIC LUPUS ERYTHEMATOSIS Systemic lupus erythematosus (disorder) Systemic lupus erythematosus (SLE) Systemic lupus erythematosus NOS Systemic lupus erythematosus synd Systemic lupus erythematosus, unspecified systemic lupus erythematosus Libman-Sacks Disease Disease, Libman-Sacks Libman Sacks Disease