Preferred Name | circumventricular organ | |
Synonyms |
circumventricular organ of neuraxis circumventricular organ CVO |
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Definitions |
Any of any of the secretory or sensory organs located in the brain region around or in relation to the ventricular system that are characterized by extensive vasculature and a lack of a normal blood brain barrier (BBB) and allow for the linkage between the central nervous system and peripheral blood flow. |
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ID |
http://purl.obolibrary.org/obo/UBERON_0005408 |
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database_cross_reference |
neuronames:1242 MESH:D066280 EMAPA:35243 BTO:0006267 NLXANAT:20090312 Wikipedia:Circumventricular_organs FMA:84081 MA:0002942 |
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definition |
Any of any of the secretory or sensory organs located in the brain region around or in relation to the ventricular system that are characterized by extensive vasculature and a lack of a normal blood brain barrier (BBB) and allow for the linkage between the central nervous system and peripheral blood flow. |
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depiction |
http://upload.wikimedia.org/wikipedia/commons/7/7d/Gray734.png |
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has exact synonym |
circumventricular organ of neuraxis circumventricular organ CVO |
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has_obo_namespace |
uberon |
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id |
UBERON:0005408 |
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in_subset | ||
label |
circumventricular organ |
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notation |
UBERON:0005408 |
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part_of | ||
prefixIRI |
UBERON:0005408 |
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prefLabel |
circumventricular organ |
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treeView | ||
UBPROP_0000008 |
All vertebrates possess at least 4 circumventricular organs (including the hypothalamus) which can monitor the contents of the cerebrospinal fluid and secrete additional substances into it. (Butler, 1996, p. 330) |
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UBPROP_0000010 |
CVOs contain neural tissue and are an integral part of neuroendocrine function; all of the CVOs, besides the subcommissural organ, contain extensive vasculature and fenestrated capillaries which leads to a leaky BBB at the site of the organs; the lack of a BBB allows CVOs to act as an alternative route for peptides and hormones in the neural tissue to the peripheral blood stream, while still protecting it from toxic substances |
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subClassOf |