loading...| Preferred Name |
Harderian gland |
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| Synonyms |
Hardarian gland glandula palpebra tertia profundus Harder's gland gland of Hardarian deep gland of the nictitating membrane |
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| Definitions |
The Harderian gland is an anterior orbital gland usually associated with the nictitating membrane, and produces and secretes a variety of substances to the eye, depending upon the species[GO]. |
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| ID |
http://purl.obolibrary.org/obo/UBERON_0004187 |
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| database_cross_reference |
UMLS:C0018597 MESH:D006243 BTO:0000557 SCTID:41474005 Wikipedia:Harderian_gland EMAPA:19153 NCIT:C77619 GAID:1219 MA:0001247 |
|
| definition |
The Harderian gland is an anterior orbital gland usually associated with the nictitating membrane, and produces and secretes a variety of substances to the eye, depending upon the species[GO]. |
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| has exact synonym |
Hardarian gland glandula palpebra tertia profundus Harder's gland gland of Hardarian |
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| has related synonym |
deep gland of the nictitating membrane |
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| has_obo_namespace |
uberon |
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| id |
UBERON:0004187 |
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| in_subset | ||
| innervated_by | ||
| label |
Harderian gland |
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| notation |
UBERON:0004187 |
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| only in taxon | ||
| part_of | ||
| prefixIRI |
UBERON:0004187 |
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| prefLabel |
Harderian gland |
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| produces | ||
| RO_0002161 |
http://purl.obolibrary.org/obo/NCBITaxon_9443 |
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| RO_0002175 |
http://purl.obolibrary.org/obo/NCBITaxon_8342 http://purl.obolibrary.org/obo/NCBITaxon_9397 http://purl.obolibrary.org/obo/NCBITaxon_8293 http://purl.obolibrary.org/obo/NCBITaxon_9681 http://purl.obolibrary.org/obo/NCBITaxon_9263 http://purl.obolibrary.org/obo/NCBITaxon_10047 |
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| treeView | ||
| UBPROP_0000008 |
In mouse the HG appears in the posterior part of eye region, in the form of nonluminated tubules between the sixteenth and eighteenth days of gestation. At birth it is still not differentiated histologically. In birds the HG originates from the conjunctival epithelium at a late embryonic stage. In the English sparrow, Passer domesticus (incubation period of about 13 days), it appears between the seventh and the eighth days of incubation. In the chick embryo (incubation period of about 21 days) it originates between the eleventh and the twelfth days.[PMID:9156609] In the limbless, burrowing amphibian Apoda (Caecilians) the harderian gland is very large, filling much of the orbit and lubricating a retractile sensory tentacle rather than the eye (Walls, 1942; Wolff, 1948). |
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| UBPROP_0000009 |
The functions attributed to the gland are many and diverse. Amongst these, it has been held to be a site of immune responses, a source of thermoregulatory lipids, a source of pheromones, a photoprotective organ and part of a retinal-pineal axis. It is arguably the last remaining large organ of widespread dis- tribution among the vertebrates to which we cannot confidently ascribe a confirmed function. In mammals, the gland excretes an oily substance used to preen the fur[WP] In some animals it acts as an accessory to the lacrimal gland, secreting fluid that eases movement of the nictitating membrane[WP] |
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| UBPROP_0000010 |
The harderian gland may be compound tubular (MacLeod, 1880; Paule, 1957) or compound tubuloacinar/tubuloalveolar (Aureli, 1957; Hoffman, 1971). |
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| subClassOf |
http://purl.obolibrary.org/obo/UBERON_0004859 http://purl.obolibrary.org/obo/UBERON_0004121 |