loading...| Preferred Name | pronephros | |
| Synonyms |
embryonic kidney archinephron pronephron pronephric kidney |
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| Definitions |
In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensible for larval life[GO]. Once the more complex mesonephros forms the pronephros undergoes apoptosis in amphibians. In fishes the nephron degenerates but the organ remains and becomes a component of the immune system[Wikipedia:Pronephros]. // TODO - check developmental relationships. Note that we previously include the ZFA/XAO terms under the more specific 'pronephric kidney', but these are now merged. TODO GCI: relationship: capable_of GO:0030104 |
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| ID |
http://purl.obolibrary.org/obo/UBERON_0002120 |
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| comment |
Once the more complex mesonephros forms the pronephros undergoes apoptosis in amphibians. In fishes the nephron degenerates but the organ remains and becomes a component of the immune system[Wikipedia:Pronephros]. // TODO - check developmental relationships. Note that we previously include the ZFA/XAO terms under the more specific 'pronephric kidney', but these are now merged. TODO GCI: relationship: capable_of GO:0030104 |
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| database_cross_reference |
BTO:0001541 ZFA:0000151 EFO:0000927 UMLS:C0231048 VHOG:0000037 Wikipedia:Pronephros EMAPA:16579 NCIT:C34280 MAT:0000117 MIAA:0000117 EHDAA2:0001570 TAO:0000151 AAO:0011089 XAO:0002000 SCTID:308804007 MESH:D060910 EHDAA:1017 FMA:72170 |
|
| definition |
In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensible for larval life[GO]. |
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| develops_from |
http://purl.obolibrary.org/obo/UBERON_0005095 |
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| external_definition |
Organ that serves as a transient kidney, providing osmoregulation during early developmental stages and then degenerating during metamorphosis.[AAO] A kidney formed of nephric tubules arising in the anterior region of the nephric ridge; forms only as a transient embryonic structure. [Evolution, Fourth_Edition_(2006)_McGraw-Hill, Function, Kardong_KV, Vertebrates:_Comparative_Anatomy, p.748][VHOG] The embryonic kidney, present at the level of the third somite, is composed of two glomeruli fused at the midline, two pronephric tubules, and paired bilateral pronephric ducts that modify the composition of the blood filtrate before delivering it to the cloaca for excretion.Kimmel et al, 1995.[TAO] |
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| has_alternative_id |
UBERON:0005794 |
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| has_exact_synonym |
pronephric kidney |
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| has_obo_namespace |
uberon |
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| has_related_synonym |
embryonic kidney archinephron pronephron |
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| has_relational_adjective |
pronephric |
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| homology_notes |
In all vertebrate embryos, the kidney begins with the differentiation of a few renal tubules from the anterior end of the nephric ridge overlying the pericardial cavity. (...) This early-developing embryonic kidney is called the pronephros.[well established][VHOG] |
|
| id |
UBERON:0002120 |
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| in_subset |
http://purl.obolibrary.org/obo/uberon/core#mouse_subset http://purl.obolibrary.org/obo/uberon/core#efo_slim http://purl.obolibrary.org/obo/uberon/core#organ_slim |
|
| label |
pronephros |
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| located in | ||
| notation |
UBERON:0002120 |
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| prefLabel |
pronephros |
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| treeView |
http://purl.obolibrary.org/obo/UBERON_0005095 |
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| subClassOf |
http://purl.obolibrary.org/obo/UBERON_0004120 |