loading...| Preferred Name |
keratinocyte |
|
| Synonyms |
malpighian cell keratinized cell of epidermis |
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| Definitions |
Keratinocytes are reportedly CDw210a-negative, CDw210b-positive, CD281-positive, CD282-positive, CD285-positive, IL22Ra1-positive, Human keratinocytes are reportedly capable of secreting BD-2, BD-3, hCAP-18, CXCL1, CXCL5, CXCL8, elafin, MMP-3, NGAL, PDGF-A, S100A7, S100A8, and S100A9. Transcription factors: STAT3-positive. An epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell. |
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| ID |
http://purl.obolibrary.org/obo/CL_0000312 |
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| comment |
Keratinocytes are reportedly CDw210a-negative, CDw210b-positive, CD281-positive, CD282-positive, CD285-positive, IL22Ra1-positive, Human keratinocytes are reportedly capable of secreting BD-2, BD-3, hCAP-18, CXCL1, CXCL5, CXCL8, elafin, MMP-3, NGAL, PDGF-A, S100A7, S100A8, and S100A9. Transcription factors: STAT3-positive. |
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| capable of |
http://purl.obolibrary.org/obo/GO_0090023 |
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| database_cross_reference |
CALOHA:TS-0500 BTO:0000667 FMA:62879 |
|
| definition |
An epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell. |
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| has_exact_synonym |
malpighian cell keratinized cell of epidermis |
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| in_subset |
http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas |
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| label |
keratinocyte |
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| part_of | ||
| prefixIRI |
CL:0000312 |
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| prefLabel |
keratinocyte |
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| present_in_taxon | ||
| treeView | ||
| subClassOf |