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Toxic Process Ontology
| Preferred Name | cytarabine | |
| Synonyms |
cytarabinum Cytosine arabinoside 4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone cytosine-beta-D-arabinofuranoside ara-C 1-beta-D-Arabinofuranosylcytosine citarabina arabinocytosine Cytosine-1-beta-D-arabinofuranoside cytarabine Arabinoside C Cytarabine 4-amino-1-beta-D-arabinofuranosylpyrimidin-2(1H)-one |
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| Definitions |
A pyrimidine nucleoside in which cytosine is attached to D-arabinofuranose via a beta-N(1)-glycosidic bond. Used mainly in the treatment of leukaemia, especially acute non-lymphoblastic leukaemia, cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. It also has antiviral and immunosuppressant properties. |
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| ID |
http://purl.obolibrary.org/obo/CHEBI_28680 |
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| database_cross_reference |
Beilstein:89175 Reaxys:89175 Drug_Central:770 DrugBank:DB00987 LINCS:LSM-5470 PMID:15492802 CAS:147-94-4
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|
| definition |
A pyrimidine nucleoside in which cytosine is attached to D-arabinofuranose via a beta-N(1)-glycosidic bond. Used mainly in the treatment of leukaemia, especially acute non-lymphoblastic leukaemia, cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. It also has antiviral and immunosuppressant properties.
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| has role |
http://purl.obolibrary.org/obo/CHEBI_35705 http://purl.obolibrary.org/obo/CHEBI_35610 |
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| has_exact_synonym |
Cytarabine 4-amino-1-beta-D-arabinofuranosylpyrimidin-2(1H)-one
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| has_related_synonym |
cytarabinum Cytosine arabinoside 4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone cytosine-beta-D-arabinofuranoside ara-C 1-beta-D-Arabinofuranosylcytosine citarabina arabinocytosine Cytosine-1-beta-D-arabinofuranoside cytarabine Arabinoside C
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|
| id |
CHEBI:28680
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|
| label |
cytarabine
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|
| notation |
CHEBI:28680
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| prefLabel |
cytarabine
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| subClassOf |
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