Preferred Name | Metronidazole | |
Synonyms |
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ID |
http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Metronidazole |
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definition |
A synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities. Although its mechanism of action is not fully elucidated, un-ionized metronidazole is readily taken up by obligate anaerobic organisms and is subsequently reduced by low-redox potential electron-transport proteins to an active, intermediate product. Reduced metronidazole causes DNA strand breaks, thereby inhibiting DNA synthesis and bacterial cell growth. |
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label |
Metronidazole |
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prefixIRI |
Metronidazole |
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prefLabel |
Metronidazole |
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reference | ||
Synonyms |
Flagyl I.V. RTU METRONIDAZOLE metronidazole Metronidazole Flagyl Tricom |
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subClassOf |
http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Antiprotozoal_Agent |
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