Sepsis Ontology

Last uploaded: May 14, 2024
Preferred Name

Cefoperazone
Synonyms
ID

http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Cefoperazone

definition

A semisynthetic, broad-spectrum, third-generation cephalosporin with antibacterial activity. Cefoperazone binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.

label

Cefoperazone

prefixIRI

Cefoperazone

prefLabel

Cefoperazone

reference

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61663

Synonyms

CEFOPERAZONE Cefoperazone

subClassOf

http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Cephalosporin_Antibiotic

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http://purl.bioontology.org/ontology/SNMI/C-53520 SNMI LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147754 NDFRT LOOM
http://purl.obolibrary.org/obo/OMIT_0003768 OMIT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.075.080.875.099.221.249.150.160 RH-MESH LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61663 NCIT LOOM
http://purl.obolibrary.org/obo/CHEBI_3493 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_3493 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_3493 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_3493 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_3493 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_3493 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_3493 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_3493 DRON LOOM
http://purl.obolibrary.org/obo/NCIT_C61663 BERO LOOM
http://purl.bioontology.org/ontology/LNC/MTHU001214 LOINC LOOM
http://purl.obolibrary.org/obo/MESH_D002438 BERO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D002438 RH-MESH LOOM
http://www.phoc.org.cn/pmo/class/PMO_00015881 PMAPP-PMO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0007552 OCHV LOOM
http://purl.jp/bio/4/id/200906013937981512 IOBC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#2564 OCHV LOOM
http://purl.obolibrary.org/obo/ARO_3004003 ARO LOOM
http://purl.bioontology.org/ontology/RXNORM/2184 RXNORM LOOM
https://go.drugbank.com/drugs/DB01329 MDM LOOM
http://stirdf.jst.go.jp/id/200907056171478516 IOBC LOOM
http://purl.bioontology.org/ontology/LNC/LP14524-0 LOINC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372743004 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/VANDF/4019662 VANDF LOOM
http://purl.bioontology.org/ontology/MESH/D002438 MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.065.589.099.249.150.160 RH-MESH LOOM
http://purl.bioontology.org/ontology/NDDF/004846 NDDF LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.886.665.074.150.160 RH-MESH LOOM
http://purl.bioontology.org/ontology/ATC/J01DD12 ATC LOOM