Sepsis Ontology

Last uploaded: May 14, 2024
Preferred Name

Cephalosporin Antibiotic
Synonyms
ID

http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Cephalosporin_Antibiotic

definition

A synthetic or semi-synthetic beta-lactam antibiotic derived from Acremonium (Cephalosporium) fungi with bactericidal activity. Cephalosporin antibiotics bind to and inactivate penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis.

label

Cephalosporin Antibiotic

prefixIRI

Cephalosporin_Antibiotic

prefLabel

Cephalosporin Antibiotic

reference

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C357

Synonyms

Cephalosporin Antibiotic cephalosporin Cephalosporins

subClassOf

http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Beta-Lactam_Antibiotic

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