Preferred Name |
Cefixime |
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Synonyms |
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ID |
http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Cefixime |
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definition |
A broad-spectrum, third-generation cephalosporin antibiotic derived semisynthetically from the marine fungus Cephalosporium acremonium with antibacterial activity. As does penicillin, the beta-lactam antibiotic cefixime inhibits bacterial cell wall synthesis by disrupting peptidoglycan synthesis, resulting in a reduction in bacterial cell wall stability and bacterial cell lysis. Stable in the presence of a variety of beta-lactamases, this agent is more active against gram-negative bacteria and less active against gram-positive bacteria compared to second-generation cephalosporins. |
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label |
Cefixime |
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prefixIRI |
Cefixime |
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prefLabel |
Cefixime |
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reference | ||
Synonyms |
Cefixime Trihydrate CEFIXIME Cefixime FK 027 Suprax cefixime |
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subClassOf |
http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Cephalosporin_Antibiotic |