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loading...| Preferred Name | Carbenicillin | |
| Synonyms |
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| ID |
http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Carbenicillin |
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| definition |
A broad-spectrum, semi-synthetic penicillin antibiotic with bactericidal and beta-lactamase resistant activity. Carbenicillin acylates the penicillin-sensitive transpeptidase C-terminal domain by opening the lactam ring. This inactivation prevents the cross-linkage of peptidoglycan strands, thereby inhibiting the third and last stage of bacterial cell wall synthesis. This leads to incomplete bacterial cell wall synthesis and eventually causes cell lysis. |
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| label |
Carbenicillin |
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| prefixIRI |
Carbenicillin |
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| prefLabel |
Carbenicillin |
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| reference | ||
| Synonyms |
CARBENICILLIN Carbenicillin Geopen Pyopen |
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| subClassOf |
http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Penicillin_Antibiotic |
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