Sepsis Ontology

Last uploaded: May 14, 2024
Preferred Name

Penicillin Antibiotic

Synonyms
ID

http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Penicillin_Antibiotic

definition

Any beta-lactam antibiotic derived from Penicillium fungi with bactericidal activity. Penicillin antibiotics bind to and inactivate penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis.

label

Penicillin Antibiotic

prefixIRI

Penicillin_Antibiotic

prefLabel

Penicillin Antibiotic

reference

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1500

Synonyms

Penicillin Antibioti penicillin

subClassOf

http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Beta-Lactam_Antibiotic

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