loading...| Preferred Name | Insertion | |
| Synonyms |
Gene Insertion Insertion Mutation |
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| Definitions |
Mutagenesis where the mutation is caused by the introduction of foreign DNA sequences into a gene or extragenic sequence. This may occur spontaneously in vivo or be experimentally induced in vivo or in vitro. Proviral DNA insertions into or adjacent to a cellular proto-oncogene can interrupt genetic translation of the coding sequences or interfere with recognition of regulatory elements and cause unregulated expression of the proto-oncogene resulting in tumor formation. |
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| ID |
http://purl.obolibrary.org/obo/SCDO_0001388 |
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| database cross reference |
MESH:D016254 |
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| definition |
Mutagenesis where the mutation is caused by the introduction of foreign DNA sequences into a gene or extragenic sequence. This may occur spontaneously in vivo or be experimentally induced in vivo or in vitro. Proviral DNA insertions into or adjacent to a cellular proto-oncogene can interrupt genetic translation of the coding sequences or interfere with recognition of regulatory elements and cause unregulated expression of the proto-oncogene resulting in tumor formation. |
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| definition source | ||
| existence in other ontologies |
Sufficient |
|
| hasExactSynonym |
Gene Insertion Insertion Mutation |
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| prefixIRI |
SCDO:0001388 |
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| prefLabel |
Insertion |
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| previous identifier |
SCDO:0001388 |
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| rdfs:label |
Insertion |
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| skos:prefLabel |
Insertion |
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| subClassOf |