Sickle Cell Disease Ontology

Last uploaded: May 6, 2021
Jump to:
loading...
Preferred Name

Amitriptyline
Synonyms
Definitions

A derivative of dibenzocycloheptadiene and a tricyclic antidepressant. Amitriptyline inhibits the re-uptake of norepinephrine and serotonin by the presynaptic neuronal membrane in the central nervous system (CNS), thereby increasing the synaptic concentration of norepinephrine and serotonin. Due to constant stimulation to these receptors, amitriptyline may produce a downregulation of adrenergic and serotonin receptors, which may contribute to the antidepressant activity.
ID

http://purl.obolibrary.org/obo/NCIT_C62005
curator note

Used to treat neuropathic pain
database cross reference

NCIT:C62005
definition

A derivative of dibenzocycloheptadiene and a tricyclic antidepressant. Amitriptyline inhibits the re-uptake of norepinephrine and serotonin by the presynaptic neuronal membrane in the central nervous system (CNS), thereby increasing the synaptic concentration of norepinephrine and serotonin. Due to constant stimulation to these receptors, amitriptyline may produce a downregulation of adrenergic and serotonin receptors, which may contribute to the antidepressant activity.
definition source

http://purl.obolibrary.org/obo/NCIT_C62005
existence in other ontologies

Sufficient
in guideline

http://purl.obolibrary.org/obo/SCDO_1000149

http://purl.obolibrary.org/obo/SCDO_1000146
prefixIRI

NCIT:C62005
prefLabel

Amitriptyline
previous identifier

SCDO:0004190
rdfs:label

Amitriptyline
treats

http://purl.obolibrary.org/obo/SCDO_0000228
subClassOf

http://purl.obolibrary.org/obo/CHEBI_23888

http://purl.obolibrary.org/obo/SCDO_0001133
Add comment
Add proposal
Delete Subject Author Type Created
No notes to display
Create mapping

Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/NCIT_C62005 BERO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_2666 EFO LOOM
https://github.com/sap218/coid/blob/master/coid.owl#COID_00643 COID LOOM
https://go.drugbank.com/drugs/DB00321 MDM LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#1027 OCHV LOOM
http://www.semanticweb.org/administrator/ontologies/2022/0/untitled-ontology-34#OWLClass21fec350_8b7f_44cc_bd43_db0646190943 WWECA LOOM
http://www.case.edu/EpSO.owl#Amitriptyline MEPO LOOM
http://www.drugbank.ca/drugs/DB00321 FTC LOOM
http://www.limics.fr/ontologies/ontoparonmed#Laroxyl ONTOPARON LOOM
https://bioportal.bioontology.org/ontologies/STMSO#Amitriptyline STMSO LOOM
http://purl.bioontology.org/ontology/MESH/D000639 MESH LOOM
http://purl.jp/bio/4/id/200906000783681540 IOBC LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62005 NCIT LOOM
http://purl.bioontology.org/ontology/VANDF/4019607 VANDF LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.426.559.847.181.384.100 RH-MESH LOOM
http://purl.obolibrary.org/obo/MESH_D000639 BERO LOOM
http://purl.bioontology.org/ontology/ATC/N06AA09 ATC LOOM
http://purl.obolibrary.org/obo/ARO_3007336 ARO LOOM
http://purl.obolibrary.org/obo/OMIT_0002055 OMIT LOOM
http://purl.obolibrary.org/obo/NCIT_C62005 BERO LOOM
http://www.co-ode.org/ontologies/galen#Amitriptyline GALEN LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372726002 SNOMEDCT LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0002600 OCHV LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Amitriptyline APAONTO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.615.181.384.100 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D000639 RH-MESH LOOM
http://www.phoc.org.cn/pmo/class/PMO_00016899 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/RCD/x01Aw RCD LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147702 NDFRT LOOM
http://purl.bioontology.org/ontology/LNC/MTHU004907 LOINC LOOM
http://purl.bioontology.org/ontology/CSP/0780-6741 CRISP LOOM
http://www.case.edu/EpilepsyOntology.owl#Amitriptyline EPSO LOOM
http://purl.bioontology.org/ontology/NDDF/004600 NDDF LOOM
http://bmi.utah.edu/ontologies/peontology/C0002600 RAO LOOM
http://purl.bioontology.org/ontology/RXNORM/704 RXNORM LOOM
http://stirdf.jst.go.jp/id/200907030405814109 IOBC LOOM
http://purl.bioontology.org/ontology/SNMI/C-62250 SNMI LOOM
http://scai.fraunhofer.de/MSOntology#Amitriptyline MSO LOOM
http://www.gamuts.net/entity#amitriptyline GAMUTS LOOM
http://purl.bioontology.org/ontology/LNC/LP14983-8 LOINC LOOM
http://purl.obolibrary.org/obo/CHEBI_2666 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_2666 HOIP LOOM
http://purl.obolibrary.org/obo/CHEBI_2666 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_2666 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_2666 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_2666 COVID-19 LOOM
http://purl.obolibrary.org/obo/CHEBI_2666 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_2666 TXPO LOOM
http://purl.obolibrary.org/obo/CHEBI_2666 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_2666 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_2666 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_2666 ODNAE LOOM