loading...| Preferred Name | Acute Chest Syndrome | |
| Synonyms |
Acute Chest Syndrome in Sickle Cell Disease |
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| Definitions |
A lung disease that involves a vasoocclusive crisis of the pulmonary vasculature seen in patients with sickle cell anemia. The crisis is initiated by a lung infection, and the resulting inflammation and loss of oxygen tension leads to sickling of red cells and further vasoocclusion. From the DO: The disease has_symptom fever, has_symptom pleuritic chest pain, has_symptom tachypnea, has_symptom cough, has_symptom hypoxemia, has_symptom marked leukocytosis, has_symptom marked leukocytosis, and has_symptom diffuse infiltrates on chest radiograph. |
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| ID |
http://purl.obolibrary.org/obo/DOID_1584 |
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| rdfs:comment |
From the DO: The disease has_symptom fever, has_symptom pleuritic chest pain, has_symptom tachypnea, has_symptom cough, has_symptom hypoxemia, has_symptom marked leukocytosis, has_symptom marked leukocytosis, and has_symptom diffuse infiltrates on chest radiograph. |
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| curator note |
This definition was given by the WG: 'Acute onset of respiratory symptoms and/or signs and an X-ray consistent with alveolar consolidation but not atelectasis, involving at least one complete lung segment." With this definition source:The acute chest syndrome in sickle cell disease: incidence and risk factors. The Cooperative Study of Sickle Cell Disease. O. Castro, D. J. Brambilla, B. Thorington, C. A. Reindorf, R. B. Scott, P. Gillette, J. C. Vera, P. S. Levy Blood. 1994 Jul 15; 84(2): 643–649. However, the definition did not seem to come from this source, so the DO term was used instead. |
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| database cross reference |
DOID:1584 |
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| definition |
A lung disease that involves a vasoocclusive crisis of the pulmonary vasculature seen in patients with sickle cell anemia. The crisis is initiated by a lung infection, and the resulting inflammation and loss of oxygen tension leads to sickling of red cells and further vasoocclusion. |
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| definition source | ||
| diagnosed using tool |
http://purl.obolibrary.org/obo/SCDO_0000217 |
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| existence in other ontologies |
Sufficient |
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| hasExactSynonym |
Acute Chest Syndrome in Sickle Cell Disease |
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| in guideline |
http://purl.obolibrary.org/obo/SCDO_1000150 http://purl.obolibrary.org/obo/SCDO_1000151 http://purl.obolibrary.org/obo/SCDO_1000154 http://purl.obolibrary.org/obo/SCDO_1000153 http://purl.obolibrary.org/obo/SCDO_1000152 http://purl.obolibrary.org/obo/SCDO_1000144 http://purl.obolibrary.org/obo/SCDO_1000149 http://purl.obolibrary.org/obo/SCDO_1000148 http://purl.obolibrary.org/obo/SCDO_1000146 |
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| prefixIRI |
DOID:1584 |
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| prefLabel |
Acute Chest Syndrome |
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| previous identifier |
SCDO:0000015 |
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| rdfs:label |
Acute Chest Syndrome |
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| skos:prefLabel |
Acute Chest Syndrome |
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| treated with |
http://purl.obolibrary.org/obo/NCIT_C15238 http://purl.obolibrary.org/obo/SCDO_0000903 http://purl.obolibrary.org/obo/SCDO_0000580 http://purl.obolibrary.org/obo/SCDO_0000576 http://purl.obolibrary.org/obo/SCDO_0000506 |
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| subClassOf |