Radiation Oncology Ontology

Last uploaded: June 19, 2018
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Preferred Name

Paclitaxel
Synonyms
Definitions

A compound extracted from the Pacific yew tree Taxus brevifolia with antineoplastic activity. Paclitaxel binds to tubulin and inhibits the disassembly of microtubules, thereby resulting in the inhibition of cell division. This agent also induces apoptosis by binding to and blocking the function of the apoptosis inhibitor protein Bcl-2 (B-cell Leukemia 2). (NCI04)
ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1411
definition

A compound extracted from the Pacific yew tree Taxus brevifolia with antineoplastic activity. Paclitaxel binds to tubulin and inhibits the disassembly of microtubules, thereby resulting in the inhibition of cell division. This agent also induces apoptosis by binding to and blocking the function of the apoptosis inhibitor protein Bcl-2 (B-cell Leukemia 2). (NCI04)
isDefinedBy

http://purl.bioontology.org/ontology/NCIT
label

Paclitaxel
prefixIRI

ncit:C1411
prefLabel

Paclitaxel
seeAlso

EuroCAT Umbrella Protocol for NSCLC
subClassOf

http://purl.bioontology.org/ontology/STY/T121

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1490
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http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1411 NCIT SAME_URI
http://purl.obolibrary.org/obo/CHEBI_45863 OBA LOOM
http://purl.obolibrary.org/obo/XCO_0000735 XCO LOOM
http://purl.obolibrary.org/obo/CHEBI_45863 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_45863 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_45863 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_45863 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_45863 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_45863 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_45863 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_45863 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_45863 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_45863 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_45863 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_45863 DIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_45863 ECTO LOOM
http://purl.obolibrary.org/obo/CHEBI_45863 HINO LOOM
http://purl.obolibrary.org/obo/CHEBI_45863 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_45863 ODNAE LOOM
http://purl.obolibrary.org/obo/CHEBI_45863 OBA LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D017239 RH-MESH LOOM
http://www.co-ode.org/ontologies/galen#Paclitaxel GALEN LOOM
http://stirdf.jst.go.jp/id/200907040288876926 IOBC LOOM
http://purl.bioontology.org/ontology/SNMI/C-78320 SNMI LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387374002 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/CSP/0093-3150 CRISP LOOM
http://purl.org/obo/owl/CHEBI#CHEBI_45863 NPO LOOM
https://go.drugbank.com/drugs/DB01229 MDM LOOM
http://purl.obolibrary.org/obo/XCO_0000735 XCO LOOM
http://www.drugbank.ca/drugs/DB01229 FTC LOOM
http://purl.obolibrary.org/obo/OMIT_0017624 OMIT LOOM
http://www.semanticweb.org/hx-jta/ontologies/thyroid_cancer_ontology#Paclitaxel TCO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0144576 OCHV LOOM
http://purl.bioontology.org/ontology/ATC/L01CD01 ATC LOOM
http://ontology.lst.tfo.upm.es/SPT/follow#Cancer_Therapy_Agent_Name_rec_met@@7 HENEGEO LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000148314 ODAE LOOM
http://purl.bioontology.org/ontology/NDDF/004116 NDDF LOOM
http://www.phoc.org.cn/pmo/class/PMO_00016747 PMAPP-PMO LOOM
http://purl.obolibrary.org/obo/NCIT_C1411 BERO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.426.392.368.242.888.777 RH-MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#16532 OCHV LOOM
http://purl.obolibrary.org/obo/MESH_D017239 BERO LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000039762 PDQ LOOM
http://purl.bioontology.org/ontology/VANDF/4020736 VANDF LOOM
http://purl.bioontology.org/ontology/RCD/h5B.. RCD LOOM
http://neuromorpho.org/ontologies/experimentconditionH.owl#NMOOt_622 NMOBR LOOM
http://purl.bioontology.org/ontology/MESH/D017239 MESH LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1411 NCIT LOOM
http://purl.bioontology.org/ontology/LNC/LP101036-4 LOINC LOOM
http://purl.bioontology.org/ontology/RXNORM/56946 RXNORM LOOM
http://ontology.lst.tfo.upm.es/BD2D/chemo#Cancer_Therapy_Agent_Name@@6 HENECON LOOM
http://purl.bioontology.org/ontology/LNC/MTHU060612 LOINC LOOM
http://purl.jp/bio/4/id/200906043304612581 IOBC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148314 NDFRT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.849.291.850.777 RH-MESH LOOM