PMO Precision Medicine Ontology

Last uploaded: December 16, 2020
Preferred Name

Apoptotic Process
Synonyms
Definitions

"A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died." [GOC:cjm, GOC:dhl, GOC:ecd, GOC:go_curators, GOC:mtg_apoptosis, GOC:tb, ISBN:0198506732, PMID:18846107, PMID:21494263]

ID

http://www.phoc.org.cn/pmo/class/PMO_00064408

Database_Cross_Reference

GO:0006915

Definition

"A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died." [GOC:cjm, GOC:dhl, GOC:ecd, GOC:go_curators, GOC:mtg_apoptosis, GOC:tb, ISBN:0198506732, PMID:18846107, PMID:21494263]

Gene Annotation

GRK5(UniProtKB:P34947)

THOC6(UniProtKB:Q86W42)

PAEP(UniProtKB:P09466)

CHIA(UniProtKB:Q9BZP6)

STK4(UniProtKB:Q13043)

SIX1(UniProtKB:Q15475)

NFKBIA(UniProtKB:P25963)

RFK(UniProtKB:Q969G6)

PPARD(UniProtKB:Q03181)

APIP(UniProtKB:Q96GX9)

MAP2K6(UniProtKB:P52564)

BBC3(UniProtKB:Q96PG8)

OPA1(UniProtKB:O60313)

NCF1(UniProtKB:P14598)

MAP2K4(UniProtKB:P45985)

RASSF6(UniProtKB:Q6ZTQ3)

ADAMTSL4(UniProtKB:Q6UY14)

NOC2L(UniProtKB:Q9Y3T9)

PDCD2(UniProtKB:Q16342)

USP17L1(UniProtKB:Q7RTZ2)

CEACAM6(UniProtKB:P40199)

GPR65(UniProtKB:Q8IYL9)

CAAP1(UniProtKB:Q9H8G2)

RASSF5(UniProtKB:Q8WWW0)

FADD(UniProtKB:Q13158)

DAB2(UniProtKB:P98082)

FKBP8(UniProtKB:Q14318)

ERCC3(UniProtKB:P19447)

AIMP1(UniProtKB:Q12904)

PEG10(UniProtKB:Q86TG7)

TAX1BP1(UniProtKB:Q86VP1)

BUB1(UniProtKB:O43683)

CDK1(UniProtKB:P06493)

IFNG(UniProtKB:P01579)

GADD45A(UniProtKB:P24522)

BCL2(UniProtKB:P10415)

BIRC6(UniProtKB:Q9NR09)

UBE2D3(UniProtKB:P61077)

ARRB1(UniProtKB:P49407)

MAGEH1(UniProtKB:Q9H213)

CSRNP1(UniProtKB:Q96S65)

PYCARD(UniProtKB:Q9ULZ3)

EGLN3(UniProtKB:Q9H6Z9)

BLID(UniProtKB:Q8IZY5)

CASP1(UniProtKB:P29466)

BNIPL(UniProtKB:Q7Z465)

C1QBP(UniProtKB:Q07021)

SHC4(UniProtKB:Q6S5L8)

TNFRSF9(UniProtKB:Q07011)

PAK6(UniProtKB:Q9NQU5)

FAF1(UniProtKB:Q9UNN5)

ZC3H8(UniProtKB:Q8N5P1)

SULF1(UniProtKB:Q8IWU6)

BCAP31(UniProtKB:P51572)

OGT(UniProtKB:O15294)

DYNLL1(UniProtKB:P63167)

TNFRSF10A(UniProtKB:O00220)

TIAM1(UniProtKB:Q13009)

MFSD10(UniProtKB:Q14728)

SRA1(UniProtKB:Q9HD15)

CSNK2A1(UniProtKB:P68400)

MECOM(UniProtKB:Q03112)

CYFIP2(UniProtKB:Q96F07)

FAIM(UniProtKB:Q9NVQ4)

SPIN2B(UniProtKB:Q9BPZ2)

PLK3(UniProtKB:Q9H4B4)

BCL2L12(UniProtKB:Q9HB09)

RTN3(UniProtKB:O95197)

HTT(UniProtKB:P42858)

PRDX5(UniProtKB:P30044)

TNS4(UniProtKB:Q8IZW8)

TNFRSF18(UniProtKB:Q9Y5U5)

UBE2Z(UniProtKB:Q9H832)

ZBTB16(UniProtKB:Q05516)

ITGB2(UniProtKB:P05107)

GZMH(UniProtKB:P20718)

EIF5A(UniProtKB:P63241)

BECN1(UniProtKB:Q14457)

SFRP5(UniProtKB:Q5T4F7)

BIRC2(UniProtKB:Q13490)

SLC5A11(UniProtKB:Q8WWX8)

FEM1B(UniProtKB:Q9UK73)

POLR2G(UniProtKB:P62487)

NFKB1(UniProtKB:P19838)

CGB3(UniProtKB:P0DN86)

TRIM39(UniProtKB:Q9HCM9)

NEK6(UniProtKB:Q9HC98)

CGB7(UniProtKB:P0DN87)

ELMO2(UniProtKB:Q96JJ3)

ADRA1A(UniProtKB:P35348)

ESPL1(UniProtKB:Q14674)

CASP7(UniProtKB:P55210)

GZMB(UniProtKB:P10144)

CASP5(UniProtKB:P51878)

IRF3(UniProtKB:Q14653)

ING4(UniProtKB:Q9UNL4)

DUX4(UniProtKB:Q9UBX2)

LGALS1(UniProtKB:P09382)

C3orf38(UniProtKB:Q5JPI3)

DAD1(UniProtKB:P61803)

SAV1(UniProtKB:Q9H4B6)

S100A14(UniProtKB:Q9HCY8)

CSRNP2(UniProtKB:Q9H175)

FIS1(UniProtKB:Q9Y3D6)

CYCS(UniProtKB:P99999)

TNFRSF10D(UniProtKB:Q9UBN6)

VDAC1(UniProtKB:P21796)

TRADD(UniProtKB:Q15628)

SLK(UniProtKB:Q9H2G2)

EI24(UniProtKB:O14681)

AIM2(UniProtKB:O14862)

PTEN(UniProtKB:P60484)

SLC5A8(UniProtKB:Q8N695)

PRKCB(UniProtKB:P05771)

IAPP(UniProtKB:P10997)

RNF144B(UniProtKB:Q7Z419)

FAS(UniProtKB:P25445)

ZDHHC16(UniProtKB:Q969W1)

APBB1(UniProtKB:O00213)

HIP1(UniProtKB:O00291)

MFN2(UniProtKB:O95140)

PRUNE2(UniProtKB:Q8WUY3)

APLP1(UniProtKB:P51693)

EBAG9(UniProtKB:O00559)

MTCH1(UniProtKB:Q9NZJ7)

HIF3A(UniProtKB:Q9Y2N7)

CAPN3(UniProtKB:P20807)

LGALS13(UniProtKB:Q9UHV8)

BEX2(UniProtKB:Q9BXY8)

DAPK2(UniProtKB:Q9UIK4)

BIRC3(UniProtKB:Q13489)

MEF2D(UniProtKB:Q14814)

ZNF385A(UniProtKB:Q96PM9)

PLEKHF1(UniProtKB:Q96S99)

PACS2(UniProtKB:Q86VP3)

RIPK1(UniProtKB:Q13546)

TNFSF10(UniProtKB:P50591)

CARD8(UniProtKB:Q9Y2G2)

TCIRG1(UniProtKB:Q13488)

CASP2(UniProtKB:P42575)

AIMP2(UniProtKB:Q13155)

TNFRSF11B(UniProtKB:O00300)

IL17A(UniProtKB:Q16552)

STK3(UniProtKB:Q13188)

CARD14(UniProtKB:Q9BXL6)

NLRC4(UniProtKB:Q9NPP4)

DLC1(UniProtKB:Q96QB1)

COMP(UniProtKB:P49747)

MZB1(UniProtKB:Q8WU39)

IL2RA(UniProtKB:P01589)

MAP2K7(UniProtKB:O14733)

PANO1(UniProtKB:I0J062)

ZNF443(UniProtKB:Q9Y2A4)

IFI27L2(UniProtKB:Q9H2X8)

NOA1(UniProtKB:Q8NC60)

CFLAR(UniProtKB:O15519)

NME6(UniProtKB:O75414)

PAX3(UniProtKB:P23760)

SLC25A6(UniProtKB:P12236)

RRAGA(UniProtKB:Q7L523)

TNFAIP8(UniProtKB:O95379)

BNIP3(UniProtKB:Q12983)

JAK2(UniProtKB:O60674)

TNFRSF25(UniProtKB:Q93038)

DAPK1(UniProtKB:P53355)

MELK(UniProtKB:Q14680)

TPT1P8(UniProtKB:Q9HAU6)

C1D(UniProtKB:Q13901)

DDIAS(UniProtKB:Q8IXT1)

TMEM102(UniProtKB:Q8N9M5)

FAM32A(UniProtKB:Q9Y421)

ERCC2(UniProtKB:P18074)

FXR1(UniProtKB:P51114)

KMT2A(UniProtKB:Q03164)

G2E3(UniProtKB:Q7L622)

CASP8(UniProtKB:Q14790)

PHLDA2(UniProtKB:Q53GA4)

CASP3(UniProtKB:P42574)

PIM1(UniProtKB:P11309)

WDR92(UniProtKB:Q96MX6)

PDCD1(UniProtKB:Q15116)

CLPTM1L(UniProtKB:Q96KA5)

PARP1(UniProtKB:P09874)

KCNIP3(UniProtKB:Q9Y2W7)

CASP10(UniProtKB:Q92851)

ARHGEF6(UniProtKB:Q15052)

SH3RF1(UniProtKB:Q7Z6J0)

RFFL(UniProtKB:Q8WZ73)

CASP4(UniProtKB:P49662)

DOCK1(UniProtKB:Q14185)

PPP2R1A(UniProtKB:P30153)

DAP(UniProtKB:P51397)

RACK1(UniProtKB:P63244)

BAG1(UniProtKB:Q99933)

NUAK2(UniProtKB:Q9H093)

TNFRSF21(UniProtKB:O75509)

FASLG(UniProtKB:P48023)

BUB1B(UniProtKB:O60566)

PPP2R2B(UniProtKB:Q00005)

IL1A(UniProtKB:P01583)

TP53AIP1(UniProtKB:Q9HCN2)

MAL(UniProtKB:P21145)

MCM2(UniProtKB:P49736)

CADM1(UniProtKB:Q9BY67)

HRK(UniProtKB:O00198)

RNF152(UniProtKB:Q8N8N0)

PUF60(UniProtKB:Q9UHX1)

TNFAIP3(UniProtKB:P21580)

BOK(UniProtKB:Q9UMX3)

DAPK3(UniProtKB:O43293)

PDCD5(UniProtKB:O14737)

FOXO1(UniProtKB:Q12778)

CIB1(UniProtKB:Q99828)

BRCA1(UniProtKB:P38398)

DIABLO(UniProtKB:Q9NR28)

BCL7B(UniProtKB:Q9BQE9)

TMBIM4(UniProtKB:Q9HC24)

P2RX1(UniProtKB:P51575)

LGALS7(UniProtKB:P47929)

NAIP(UniProtKB:Q13075)

IRF1(UniProtKB:P10914)

NLRP3(UniProtKB:Q96P20)

ITGB3BP(UniProtKB:Q13352)

DPF1(UniProtKB:Q92782)

IER3(UniProtKB:P46695)

RPS6KA3(UniProtKB:P51812)

DPF2(UniProtKB:Q92785)

MRPL41(UniProtKB:Q8IXM3)

IL24(UniProtKB:Q13007)

CIAPIN1(UniProtKB:Q6FI81)

TRAF5(UniProtKB:O00463)

PRELID1(UniProtKB:Q9Y255)

CST3(UniProtKB:P01034)

BABAM2(UniProtKB:Q9NXR7)

TMEM214(UniProtKB:Q6NUQ4)

RALB(UniProtKB:P11234)

PDCD4(UniProtKB:Q53EL6)

SH3RF3(UniProtKB:Q8TEJ3)

NOD1(UniProtKB:Q9Y239)

TRIM69(UniProtKB:Q86WT6)

BIRC8(UniProtKB:Q96P09)

TNFAIP1(UniProtKB:Q13829)

S100A9(UniProtKB:P06702)

TP63(UniProtKB:Q9H3D4)

STEAP3(UniProtKB:Q658P3)

IFNA2(UniProtKB:P01563)

PPP2CA(UniProtKB:P67775)

HIPK3(UniProtKB:Q9H422)

RNF216(UniProtKB:Q9NWF9)

MIEN1(UniProtKB:Q9BRT3)

GRAMD4(UniProtKB:Q6IC98)

TMEM14A(UniProtKB:Q9Y6G1)

ADORA2A(UniProtKB:P29274)

BCL2L13(UniProtKB:Q9BXK5)

PAK5(UniProtKB:Q9P286)

TAF10(UniProtKB:Q12962)

BCL2L14(UniProtKB:Q9BZR8)

UNC5B(UniProtKB:Q8IZJ1)

BCLAF1(UniProtKB:Q9NYF8)

BCAP29(UniProtKB:Q9UHQ4)

FGFR2(UniProtKB:P21802)

NUDT2(UniProtKB:P50583)

EFNA5(UniProtKB:P52803)

PAWR(UniProtKB:Q96IZ0)

ATCAY(UniProtKB:Q86WG3)

CITED1(UniProtKB:Q99966)

RABEP1(UniProtKB:Q15276)

BAG6(UniProtKB:P46379)

PRF1(UniProtKB:P14222)

SH3GLB1(UniProtKB:Q9Y371)

MAPK3(UniProtKB:P27361)

BNIP2(UniProtKB:Q12982)

IFI6(UniProtKB:P09912)

GREM1(UniProtKB:O60565)

TIGAR(UniProtKB:Q9NQ88)

NISCH(UniProtKB:Q9Y2I1)

PRKCE(UniProtKB:Q02156)

LTA(UniProtKB:P01374)

API5(UniProtKB:Q9BZZ5)

EPHA7(UniProtKB:Q15375)

CIDEC(UniProtKB:Q96AQ7)

GAS2(UniProtKB:O43903)

NOTCH2(UniProtKB:Q04721)

PSMD10(UniProtKB:O75832)

CASP6(UniProtKB:P55212)

GLRX2(UniProtKB:Q9NS18)

TAOK2(UniProtKB:Q9UL54)

KRT20(UniProtKB:P35900)

HIP1R(UniProtKB:O75146)

XAF1(UniProtKB:Q6GPH4)

BMX(UniProtKB:P51813)

PLAGL1(UniProtKB:Q9UM63)

CD5L(UniProtKB:O43866)

TNFRSF10B(UniProtKB:O14763)

IL1B(UniProtKB:P01584)

GML(UniProtKB:Q99445)

KIF1B(UniProtKB:O60333)

SUDS3(UniProtKB:Q9H7L9)

EVA1A(UniProtKB:Q9H8M9)

HTATIP2(UniProtKB:Q9BUP3)

DPP8(UniProtKB:Q6V1X1)

AVEN(UniProtKB:Q9NQS1)

CDIP1(UniProtKB:Q9H305)

UNC5A(UniProtKB:Q6ZN44)

EPB41L3(UniProtKB:Q9Y2J2)

GZMA(UniProtKB:P12544)

TGFBR2(UniProtKB:P37173)

MYD88(UniProtKB:Q99836)

TOX3(UniProtKB:O15405)

CHEK1(UniProtKB:O14757)

GJB6(UniProtKB:O95452)

IFT57(UniProtKB:Q9NWB7)

NLRP2(UniProtKB:Q9NX02)

RTKN(UniProtKB:Q9BST9)

USP17L24(UniProtKB:Q0WX57)

GHITM(UniProtKB:Q9H3K2)

C5AR1(UniProtKB:P21730)

CSRNP3(UniProtKB:Q8WYN3)

ARL6IP1(UniProtKB:Q15041)

TRAF7(UniProtKB:Q6Q0C0)

JTB(UniProtKB:O76095)

CDK11B(UniProtKB:P21127)

GADD45G(UniProtKB:O95257)

SIAH1(UniProtKB:Q8IUQ4)

STK26(UniProtKB:Q9P289)

PRAME(UniProtKB:P78395)

SAP30BP(UniProtKB:Q9UHR5)

SNCA(UniProtKB:P37840)

MAP1S(UniProtKB:Q66K74)

RBM5(UniProtKB:P52756)

LGALS16(UniProtKB:A8MUM7)

RNF183(UniProtKB:Q96D59)

UXT(UniProtKB:Q9UBK9)

CD2(UniProtKB:P06729)

IFI27(UniProtKB:P40305)

AXIN1(UniProtKB:O15169)

TRIM35(UniProtKB:Q9UPQ4)

RTN4(UniProtKB:Q9NQC3)

BIK(UniProtKB:Q13323)

PLSCR1(UniProtKB:O15162)

KANK2(UniProtKB:Q63ZY3)

PRKCD(UniProtKB:Q05655)

MEF2A(UniProtKB:Q02078)

PRKD1(UniProtKB:Q15139)

FAIM2(UniProtKB:Q9BWQ8)

MEF2C(UniProtKB:Q06413)

IKBKG(UniProtKB:Q9Y6K9)

INPP5D(UniProtKB:Q92835)

DCC(UniProtKB:P43146)

MAP3K10(UniProtKB:Q02779)

SQSTM1(UniProtKB:Q13501)

CHMP3(UniProtKB:Q9Y3E7)

PCSK9(UniProtKB:Q8NBP7)

MX1(UniProtKB:P20591)

BFAR(UniProtKB:Q9NZS9)

FAM3B(UniProtKB:P58499)

CTSH(UniProtKB:P09668)

PPID(UniProtKB:Q08752)

VIL1(UniProtKB:P09327)

LALBA(UniProtKB:P00709)

PTPN6(UniProtKB:P29350)

ELMO1(UniProtKB:Q92556)

SHF(UniProtKB:Q7M4L6)

TGFBR1(UniProtKB:P36897)

BRMS1(UniProtKB:Q9HCU9)

CDK11A(UniProtKB:Q9UQ88)

DDX41(UniProtKB:Q9UJV9)

RHBDD1(UniProtKB:Q8TEB9)

RNF130(UniProtKB:Q86XS8)

TRAF4(UniProtKB:Q9BUZ4)

C19orf12(UniProtKB:Q9NSK7)

TP53INP1(UniProtKB:Q96A56)

UNC5C(UniProtKB:O95185)

DDIT4(UniProtKB:Q9NX09)

RNF34(UniProtKB:Q969K3)

TLR2(UniProtKB:O60603)

RPS6KB1(UniProtKB:P23443)

RAF1(UniProtKB:P04049)

CDCA7(UniProtKB:Q9BWT1)

MUL1(UniProtKB:Q969V5)

BRAT1(UniProtKB:Q6PJG6)

TRIAP1(UniProtKB:O43715)

GJA1(UniProtKB:P17302)

SHB(UniProtKB:Q15464)

ITCH(UniProtKB:Q96J02)

MINDY3(UniProtKB:Q9H8M7)

TPX2(UniProtKB:Q9ULW0)

ADAM15(UniProtKB:Q13444)

NR3C1(UniProtKB:P04150)

NME3(UniProtKB:Q13232)

SH3KBP1(UniProtKB:Q96B97)

IL19(UniProtKB:Q9UHD0)

DRAM1(UniProtKB:Q8N682)

SEPT4(UniProtKB:O43236)

MTFP1(UniProtKB:Q9UDX5)

PTK2B(UniProtKB:Q14289)

THOC1(UniProtKB:Q96FV9)

TNFSF15(UniProtKB:O95150)

PDCL3(UniProtKB:Q9H2J4)

IFI27L1(UniProtKB:Q96BM0)

PKN2(UniProtKB:Q16513)

BCL2L15(UniProtKB:Q5TBC7)

TNFSF12(UniProtKB:O43508)

EAF2(UniProtKB:Q96CJ1)

NCKAP1(UniProtKB:Q9Y2A7)

BAX(UniProtKB:Q07812)

PMAIP1(UniProtKB:Q13794)

GULP1(UniProtKB:Q9UBP9)

TNFRSF19(UniProtKB:Q9NS68)

DAXX(UniProtKB:Q9UER7)

CHI3L1(UniProtKB:P36222)

RYBP(UniProtKB:Q8N488)

ATG4D(UniProtKB:Q86TL0)

CTSC(UniProtKB:P53634)

BIRC7(UniProtKB:Q96CA5)

PAK2(UniProtKB:Q13177)

PRDX3(UniProtKB:P30048)

RPS3(UniProtKB:P23396)

TRAF1(UniProtKB:Q13077)

ELMO3(UniProtKB:Q96BJ8)

TMEM219(UniProtKB:Q86XT9)

MAP3K9(UniProtKB:P80192)

DNASE1(UniProtKB:P24855)

GADD45B(UniProtKB:O75293)

TIA1(UniProtKB:P31483)

GAS6(UniProtKB:Q14393)

MAPK14(UniProtKB:Q16539)

DPEP1(UniProtKB:P16444)

TIAF1(UniProtKB:O95411)

TCHP(UniProtKB:Q9BT92)

PAK4(UniProtKB:O96013)

IGFBP3(UniProtKB:P17936)

LGALS14(UniProtKB:Q8TCE9)

CTNNBL1(UniProtKB:Q8WYA6)

FBXO10(UniProtKB:Q9UK96)

PSME3(UniProtKB:P61289)

MYDGF(UniProtKB:Q969H8)

USP17L2(UniProtKB:Q6R6M4)

AHR(UniProtKB:P35869)

EDAR(UniProtKB:Q9UNE0)

MT3(UniProtKB:P25713)

PEG3(UniProtKB:Q9GZU2)

MRPS30(UniProtKB:Q9NP92)

ZC3H12A(UniProtKB:Q5D1E8)

RRP1B(UniProtKB:Q14684)

NOX5(UniProtKB:Q96PH1)

EP300(UniProtKB:Q09472)

CIDEB(UniProtKB:Q9UHD4)

PEA15(UniProtKB:Q15121)

USP17L5(UniProtKB:A8MUK1)

ZFP36L1(UniProtKB:Q07352)

TRAIP(UniProtKB:Q9BWF2)

DRAM2(UniProtKB:Q6UX65)

USP17L3(UniProtKB:A6NCW0)

DHCR24(UniProtKB:Q15392)

RASSF7(UniProtKB:Q02833)

C6orf120(UniProtKB:Q7Z4R8)

RIPK2(UniProtKB:O43353)

NSG1(UniProtKB:P42857)

UNC5D(UniProtKB:Q6UXZ4)

PTPRH(UniProtKB:Q9HD43)

S100A8(UniProtKB:P05109)

GSDMA(UniProtKB:Q96QA5)

TNFRSF6B(UniProtKB:O95407)

CXCR3(UniProtKB:P49682)

SERPINB9(UniProtKB:P50453)

FATE1(UniProtKB:Q969F0)

PPP1R13L(UniProtKB:Q8WUF5)

SIAH2(UniProtKB:O43255)

CIDEA(UniProtKB:O60543)

BNIP1(UniProtKB:Q12981)

TCIM(UniProtKB:Q9NR00)

RAD21(UniProtKB:O60216)

PPP1R15A(UniProtKB:O75807)

BCL7C(UniProtKB:Q8WUZ0)

RRAGC(UniProtKB:Q9HB90)

SEMA3A(UniProtKB:Q14563)

AKTIP(UniProtKB:Q9H8T0)

AREL1(UniProtKB:O15033)

RPS6KA1(UniProtKB:Q15418)

YARS(UniProtKB:P54577)

ALOX15B(UniProtKB:O15296)

CASP14(UniProtKB:P31944)

KLF11(UniProtKB:O14901)

GDF6(UniProtKB:Q6KF10)

CD14(UniProtKB:P08571)

AVP(UniProtKB:P01185)

SMNDC1(UniProtKB:O75940)

EMC4(UniProtKB:Q5J8M3)

CXCR4(UniProtKB:P61073)

TOPAZ1(UniProtKB:Q8N9V7)

STK17B(UniProtKB:O94768)

RHOB(UniProtKB:P62745)

BCL2L11(UniProtKB:O43521)

PHLDA1(UniProtKB:Q8WV24)

TAF6(UniProtKB:P49848)

RMDN3(UniProtKB:Q96TC7)

NLRP1(UniProtKB:Q9C000)

PDE1B(UniProtKB:Q01064)

MT-RNR2(UniProtKB:Q8IVG9)

PDCD6IP(UniProtKB:Q8WUM4)

CKAP2(UniProtKB:Q8WWK9)

RELT(UniProtKB:Q969Z4)

NTN1(UniProtKB:O95631)

CSNK2A2(UniProtKB:P19784)

TFAP2B(UniProtKB:Q92481)

PDCD7(UniProtKB:Q8N8D1)

ROCK1(UniProtKB:Q13464)

TFPT(UniProtKB:P0C1Z6)

ASAH2(UniProtKB:Q9NR71)

STK17A(UniProtKB:Q9UEE5)

PLSCR3(UniProtKB:Q9NRY6)

SLTM(UniProtKB:Q9NWH9)

HINT2(UniProtKB:Q9BX68)

CCAR1(UniProtKB:Q8IX12)

APAF1(UniProtKB:O14727)

JADE1(UniProtKB:Q6IE81)

EPO(UniProtKB:P01588)

CASR(UniProtKB:P41180)

TNFSF14(UniProtKB:O43557)

SEMA6A(UniProtKB:Q9H2E6)

BAK1(UniProtKB:Q16611)

CARD6(UniProtKB:Q9BX69)

MAGI3(UniProtKB:Q5TCQ9)

CASP12(UniProtKB:Q6UXS9)

KLLN(UniProtKB:B2CW77)

TRAF3(UniProtKB:Q13114)

TCTN3(UniProtKB:Q6NUS6)

PIM3(UniProtKB:Q86V86)

GZMM(UniProtKB:P51124)

BAD(UniProtKB:Q92934)

LTBR(UniProtKB:P36941)

PTRH2(UniProtKB:Q9Y3E5)

CASP9(UniProtKB:P55211)

SFRP2(UniProtKB:Q96HF1)

PIDD1(UniProtKB:Q9HB75)

SGMS1(UniProtKB:Q86VZ5)

TNIP2(UniProtKB:Q8NFZ5)

ECSCR(UniProtKB:Q19T08)

PAK1(UniProtKB:Q13153)

TIAL1(UniProtKB:Q01085)

BIRC5(UniProtKB:O15392)

ZMAT3(UniProtKB:Q9HA38)

AIFM1(UniProtKB:O95831)

ATG5(UniProtKB:Q9H1Y0)

CEACAM5(UniProtKB:P06731)

MAPK1(UniProtKB:P28482)

NGB(UniProtKB:Q9NPG2)

XIAP(UniProtKB:P98170)

PHLPP1(UniProtKB:O60346)

ZFAND6(UniProtKB:Q6FIF0)

KREMEN1(UniProtKB:Q96MU8)

ZSWIM2(UniProtKB:Q8NEG5)

SGK1(UniProtKB:O00141)

label

Apoptotic Process

MCID

MC04783859

PMOID

PMO:00064408

prefixIRI

pmo:PMO_00064408

prefLabel

Apoptotic Process

Synonym

"signaling (initiator) caspase activity" RELATED []

"apoptosis" NARROW []

"type I programmed cell death" NARROW []

"apoptosis activator activity" RELATED []

"cell suicide" BROAD []

"apoptosis signaling" NARROW []

"apoptotic program" NARROW [GOC:add]

"commitment to apoptosis" RELATED []

"induction of apoptosis" RELATED []

"apoptotic cell death" EXACT [GOC:sl]

"apoptotic programmed cell death" EXACT []

"programmed cell death by apoptosis" EXACT []

"cellular suicide" BROAD []

"caspase-dependent programmed cell death" RELATED []

"induction of apoptosis by p53" RELATED []

"activation of apoptosis" NARROW []

Tree Number

T10.1.29.54.2.5

subClassOf

http://www.phoc.org.cn/pmo/class/PMO_00064406

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/GO_0006915 UBERON LOOM
http://purl.obolibrary.org/obo/GO_0006915 CL LOOM
http://purl.obolibrary.org/obo/GO_0006915 OBA LOOM
http://purl.obolibrary.org/obo/GO_0006915 CLO LOOM
http://purl.obolibrary.org/obo/GO_0006915 PLANP LOOM
http://purl.obolibrary.org/obo/GO_0006915 GCBO LOOM
http://purl.obolibrary.org/obo/GO_0006915 CCONT LOOM
http://purl.obolibrary.org/obo/GO_0006915 FOVT LOOM
http://purl.obolibrary.org/obo/GO_0006915 HOIP LOOM
http://purl.obolibrary.org/obo/GO_0006915 RBO LOOM
http://purl.obolibrary.org/obo/GO_0006915 OBI_BCGO LOOM
http://purl.obolibrary.org/obo/GO_0006915 EFO LOOM
http://purl.obolibrary.org/obo/GO_0006915 XPO LOOM
http://purl.obolibrary.org/obo/GO_0006915 PHAGE LOOM
http://purl.obolibrary.org/obo/GO_0006915 CMPO LOOM
http://purl.obolibrary.org/obo/GO_0006915 COVID-19 LOOM
http://purl.obolibrary.org/obo/GO_0006915 PCL LOOM
http://purl.obolibrary.org/obo/GO_0006915 PATO LOOM
http://purl.obolibrary.org/obo/GO_0006915 BAO LOOM
http://purl.obolibrary.org/obo/GO_0006915 NIFDYS LOOM
http://purl.obolibrary.org/obo/GO_0006915 GO-PLUS LOOM
http://purl.obolibrary.org/obo/GO_0006915 BERO LOOM
http://purl.obolibrary.org/obo/GO_0006915 HHEAR LOOM
http://purl.obolibrary.org/obo/GO_0006915 TXPO LOOM
http://purl.obolibrary.org/obo/GO_0006915 INO LOOM
http://purl.obolibrary.org/obo/GO_0006915 UPHENO LOOM
http://purl.obolibrary.org/obo/GO_0006915 FTC LOOM
http://purl.obolibrary.org/obo/GO_0006915 NIFSTD LOOM
http://purl.obolibrary.org/obo/GO_0006915 ECAO LOOM
http://purl.obolibrary.org/obo/GO_0006915 KTAO LOOM
http://purl.obolibrary.org/obo/GO_0006915 FYPO LOOM
http://purl.obolibrary.org/obo/GO_0006915 REGN_GO LOOM
http://purl.obolibrary.org/obo/GO_0006915 HINO LOOM
http://purl.obolibrary.org/obo/GO_0006915 MAXO LOOM
http://purl.obolibrary.org/obo/GO_0006915 GO LOOM
http://purl.obolibrary.org/obo/GO_0006915 ZP LOOM
http://purl.obolibrary.org/obo/GO_0006915 AISM LOOM
http://purl.obolibrary.org/obo/GO_0006915 NMDCO LOOM