PMO Precision Medicine Ontology

Last uploaded: December 16, 2020
Preferred Name

Tumor Necrosis Factor-mediated Signaling Pathway
Synonyms
Definitions

"A series of molecular signals initiated by the binding of a tumor necrosis factor to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:mah, GOC:signaling]

ID

http://www.phoc.org.cn/pmo/class/PMO_00063901

Database_Cross_Reference

GO:0033209

Definition

"A series of molecular signals initiated by the binding of a tumor necrosis factor to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:mah, GOC:signaling]

Gene Annotation

PSME1(UniProtKB:Q06323)

NFKBIA(UniProtKB:P25963)

ILK(UniProtKB:Q13418)

TNFRSF8(UniProtKB:P28908)

PSMD5(UniProtKB:Q16401)

CD27(UniProtKB:P26842)

PSMC3(UniProtKB:P17980)

PSME2(UniProtKB:Q9UL46)

TNFRSF12A(UniProtKB:Q9NP84)

PSMD13(UniProtKB:Q9UNM6)

EDA2R(UniProtKB:Q9HAV5)

PYCARD(UniProtKB:Q9ULZ3)

PSMB11(UniProtKB:A5LHX3)

PSMD12(UniProtKB:O00232)

PSMF1(UniProtKB:Q92530)

TNFRSF9(UniProtKB:Q07011)

TNFRSF17(UniProtKB:Q02223)

PSMC1(UniProtKB:P62191)

TNFRSF18(UniProtKB:Q9Y5U5)

TNFRSF1B(UniProtKB:P20333)

PSMA7(UniProtKB:O14818)

PSMB2(UniProtKB:P49721)

BAG4(UniProtKB:O95429)

BIRC2(UniProtKB:Q13490)

TNFRSF14(UniProtKB:Q92956)

PSMD4(UniProtKB:P55036)

PSMC2(UniProtKB:P35998)

TNFSF8(UniProtKB:P32971)

TRADD(UniProtKB:Q15628)

PSMA3(UniProtKB:P25788)

TNFSF13B(UniProtKB:Q9Y275)

AIM2(UniProtKB:O14862)

ST18(UniProtKB:O60284)

BIRC3(UniProtKB:Q13489)

RIPK1(UniProtKB:Q13546)

TNFRSF11B(UniProtKB:O00300)

CARD14(UniProtKB:Q9BXL6)

PSMA8(UniProtKB:Q8TAA3)

PSMD11(UniProtKB:O00231)

JAK2(UniProtKB:O60674)

TNFRSF25(UniProtKB:Q93038)

PSMD8(UniProtKB:P48556)

CD40LG(UniProtKB:P29965)

TNFRSF13C(UniProtKB:Q96RJ3)

PSME4(UniProtKB:Q14997)

TNFSF9(UniProtKB:P41273)

FOXO3(UniProtKB:O43524)

IKBKB(UniProtKB:O14920)

EDARADD(UniProtKB:Q8WWZ3)

LIMS1(UniProtKB:P48059)

PSMD14(UniProtKB:O00487)

PSMD6(UniProtKB:Q15008)

TNFSF11(UniProtKB:O14788)

CHUK(UniProtKB:O15111)

LTA(UniProtKB:P01374)

PSMA1(UniProtKB:P25786)

KRT8(UniProtKB:P05787)

STAT1(UniProtKB:P42224)

PSMD10(UniProtKB:O75832)

PSMA2(UniProtKB:P25787)

TXNDC17(UniProtKB:Q9BRA2)

CD70(UniProtKB:P32970)

KARS(UniProtKB:Q15046)

PSMD7(UniProtKB:P51665)

LTB(UniProtKB:Q06643)

CDIP1(UniProtKB:Q9H305)

MAP3K14(UniProtKB:Q99558)

ACTN4(UniProtKB:O43707)

PSMD9(UniProtKB:O00233)

PSMD2(UniProtKB:Q13200)

PSMB8(UniProtKB:P28062)

TNF(UniProtKB:P01375)

PSMB3(UniProtKB:P49720)

PSMA5(UniProtKB:P28066)

PSMC5(UniProtKB:P62195)

ADAM17(UniProtKB:P78536)

PSMB10(UniProtKB:P40306)

PYDC1(UniProtKB:Q8WXC3)

PSMB4(UniProtKB:P28070)

KRT18(UniProtKB:P05783)

TNFSF18(UniProtKB:Q9UNG2)

PTK2B(UniProtKB:Q14289)

TNFSF15(UniProtKB:O95150)

TNFSF12(UniProtKB:O43508)

TNFSF13(UniProtKB:O75888)

TNFSF4(UniProtKB:P23510)

TNFRSF19(UniProtKB:Q9NS68)

PSMD1(UniProtKB:Q99460)

TNFRSF13B(UniProtKB:O14836)

PSMA4(UniProtKB:P25789)

CD40(UniProtKB:P25942)

PSMB1(UniProtKB:P20618)

PSME3(UniProtKB:P61289)

PSMD3(UniProtKB:O43242)

EDAR(UniProtKB:Q9UNE0)

PSMB6(UniProtKB:P28072)

PLVAP(UniProtKB:Q9BX97)

TNFRSF11A(UniProtKB:Q9Y6Q6)

PSMB9(UniProtKB:P28065)

PSMB5(UniProtKB:P28074)

TNFRSF1A(UniProtKB:P19438)

TNFRSF6B(UniProtKB:O95407)

PSMC4(UniProtKB:P43686)

TRAF2(UniProtKB:Q12933)

COMMD7(UniProtKB:Q86VX2)

RELA(UniProtKB:Q04206)

TMSB4X(UniProtKB:P62328)

TNFSF14(UniProtKB:O43557)

TRAF3(UniProtKB:Q13114)

LTBR(UniProtKB:P36941)

PSMA6(UniProtKB:P60900)

EDA(UniProtKB:Q92838)

TNFRSF4(UniProtKB:P43489)

PSMC6(UniProtKB:P62333)

PSMB7(UniProtKB:Q99436)

label

Tumor Necrosis Factor-mediated Signaling Pathway

MCID

MC04797434

PMOID

PMO:00063901

prefixIRI

pmo:PMO_00063901

prefLabel

Tumor Necrosis Factor-mediated Signaling Pathway

Synonym

"TNF-alpha-mediated signaling pathway" NARROW []

"adipocytokine signaling pathway" RELATED []

"tumor necrosis factor-mediated signalling pathway" EXACT [GOC:mah]

"tumor necrosis factor alpha-mediated signaling pathway" NARROW []

Tree Number

T10.1.26.1.33.23.24.24.5

T10.1.29.20.24.24.5

subClassOf

http://www.phoc.org.cn/pmo/class/PMO_00063900

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