loading...| Preferred Name |
Cytokine-mediated Signaling Pathway |
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| Synonyms |
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| Definitions |
"A series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:mah, GOC:signaling, PMID:19295629] |
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| ID |
http://www.phoc.org.cn/pmo/class/PMO_00063900 |
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| Database_Cross_Reference |
GO:0019221 |
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| Definition |
"A series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:mah, GOC:signaling, PMID:19295629] |
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| Gene Annotation |
IL2(UniProtKB:P60568) KIT(UniProtKB:P10721) IL1RAPL2(UniProtKB:Q9NP60) IL18(UniProtKB:Q14116) SDC1(UniProtKB:P18827) CCL11(UniProtKB:P51671) TIMP1(UniProtKB:P01033) GRB2(UniProtKB:P62993) IFNGR1(UniProtKB:P15260) IL3RA(UniProtKB:P26951) MMP9(UniProtKB:P14780) ZEB1(UniProtKB:P37275) GHR(UniProtKB:P10912) TYK2(UniProtKB:P29597) IL36RN(UniProtKB:Q9UBH0) IFNE(UniProtKB:Q86WN2) SOS1(UniProtKB:Q07889) RORC(UniProtKB:P51449) CCL5(UniProtKB:P13501) FN1(UniProtKB:P02751) HIF1A(UniProtKB:Q16665) IFNA6(UniProtKB:P05013) BCL2(UniProtKB:P10415) SHC1(UniProtKB:P29353) BCL2L1(UniProtKB:Q07817) CASP1(UniProtKB:P29466) IL2RB(UniProtKB:P14784) POU2F1(UniProtKB:P14859) CCL3L1(UniProtKB:P16619) DUOX1(UniProtKB:Q9NRD9) TEC(UniProtKB:P42680) MCL1(UniProtKB:Q07820) TGFB1(UniProtKB:P01137) IL10RB(UniProtKB:Q08334) MMP1(UniProtKB:P03956) IL7(UniProtKB:P13232) CD86(UniProtKB:P42081) HGF(UniProtKB:P14210) IFNL2(UniProtKB:Q8IZJ0) IL11(UniProtKB:P20809) TNFRSF1B(UniProtKB:P20333) CCR1(UniProtKB:P32246) RHOU(UniProtKB:Q7L0Q8) ITGB2(UniProtKB:P05107) FOS(UniProtKB:P01100) IL4(UniProtKB:P05112) PRKACA(UniProtKB:P17612) CNTF(UniProtKB:P26441) ICAM1(UniProtKB:P05362) IL20RA(UniProtKB:Q9UHF4) JAK1(UniProtKB:P23458) EREG(UniProtKB:O14944) OSM(UniProtKB:P13725) CD4(UniProtKB:P01730) YWHAZ(UniProtKB:P63104) IL20RB(UniProtKB:Q6UXL0) CD80(UniProtKB:P33681) IL36G(UniProtKB:Q9NZH8) CRKL(UniProtKB:P46109) CCL3(UniProtKB:P10147) ALOX5(UniProtKB:P09917) MYC(UniProtKB:P01106) IFNAR2(UniProtKB:P48551) IL31RA(UniProtKB:Q8NI17) CXCL8(UniProtKB:P10145) CCL4(UniProtKB:P13236) IFNA7(UniProtKB:P01567) IFNA4(UniProtKB:P05014) SOCS1(UniProtKB:O15524) CNTFR(UniProtKB:P26992) ITGAX(UniProtKB:P20702) IL6R(UniProtKB:P08887) IL34(UniProtKB:Q6ZMJ4) IFNW1(UniProtKB:P05000) IL1R2(UniProtKB:P27930) HSP90AA1(UniProtKB:P07900) IL17A(UniProtKB:Q16552) PF4(UniProtKB:P02776) CLCF1(UniProtKB:Q9UBD9) IL4R(UniProtKB:P24394) STAT3(UniProtKB:P40763) IRAK2(UniProtKB:O43187) IL2RA(UniProtKB:P01589) CNOT9(UniProtKB:Q92600) JUNB(UniProtKB:P17275) TP53(UniProtKB:P04637) RORA(UniProtKB:P35398) VEGFA(UniProtKB:P15692) JAK2(UniProtKB:O60674) MAOA(UniProtKB:P21397) IL6(UniProtKB:P05231) F3(UniProtKB:P13726) CASP3(UniProtKB:P42574) PIM1(UniProtKB:P11309) CSF1R(UniProtKB:P07333) TXLNA(UniProtKB:P40222) IL1RL2(UniProtKB:Q9HB29) LAMA5(UniProtKB:O15230) IRAK3(UniProtKB:Q9Y616) IL22RA2(UniProtKB:Q969J5) FLT3(UniProtKB:P36888) FASLG(UniProtKB:P48023) IL1A(UniProtKB:P01583) UBA52(UniProtKB:P62987) IRF4(UniProtKB:Q15306) CCL22(UniProtKB:O00626) FOXO1(UniProtKB:Q12778) FOXO3(UniProtKB:O43524) CSF2RB(UniProtKB:P32927) CEBPD(UniProtKB:P49716) FYN(UniProtKB:P06241) IL32(UniProtKB:P24001) IFNA1(UniProtKB:P01562) IL3(UniProtKB:P08700) IL24(UniProtKB:Q13007) BCL6(UniProtKB:P41182) IL12RB1(UniProtKB:P42701) F13A1(UniProtKB:P00488) COL1A2(UniProtKB:P08123) IGHG4(UniProtKB:P01861) IFNA21(UniProtKB:P01568) IFNA2(UniProtKB:P01563) IL5(UniProtKB:P05113) CSF2RA(UniProtKB:P15509) NUMBL(UniProtKB:Q9Y6R0) IFNA16(UniProtKB:P05015) PTPRZ1(UniProtKB:P23471) LBP(UniProtKB:P18428) IL1RAP(UniProtKB:Q9NPH3) FLT3LG(UniProtKB:P49771) CSF1(UniProtKB:P09603) CCR2(UniProtKB:P41597) TNFSF11(UniProtKB:O14788) IFNB1(UniProtKB:P01574) IL31(UniProtKB:Q6EBC2) JAK3(UniProtKB:P52333) STAT1(UniProtKB:P42224) CSF3R(UniProtKB:Q99062) IGHE(UniProtKB:P01854) LIF(UniProtKB:P15018) FZD4(UniProtKB:Q9ULV1) FGF2(UniProtKB:P09038) IL1R1(UniProtKB:P14778) IL13RA2(UniProtKB:Q14627) CCL2(UniProtKB:P13500) ALOX15(UniProtKB:P16050) IL1B(UniProtKB:P01584) IL23R(UniProtKB:Q5VWK5) HSP90B1(UniProtKB:P14625) CD36(UniProtKB:P16671) IL13RA1(UniProtKB:P78552) A0A2R8YE73(UniProtKB:A0A2R8YE73) CXCL10(UniProtKB:P02778) PIK3CD(UniProtKB:O00329) IFNLR1(UniProtKB:Q8IU57) IL17REL(UniProtKB:Q6ZVW7) IL1RN(UniProtKB:P18510) IL5RA(UniProtKB:Q01344) CEBPA(UniProtKB:P49715) PTPRN(UniProtKB:Q16849) IL1F10(UniProtKB:Q8WWZ1) MMP2(UniProtKB:P08253) EDN2(UniProtKB:P20800) TNF(UniProtKB:P01375) INPPL1(UniProtKB:O15357) VIM(UniProtKB:P08670) GAB2(UniProtKB:Q9UQC2) CCL20(UniProtKB:P78556) IFNA8(UniProtKB:P32881) ITGB1(UniProtKB:P05556) IL13(UniProtKB:P35225) PIK3R1(UniProtKB:P27986) OPRD1(UniProtKB:P41143) H0Y3Z8(UniProtKB:H0Y3Z8) CXCL2(UniProtKB:P19875) INPP5D(UniProtKB:Q92835) IL23A(UniProtKB:Q9NPF7) MMP3(UniProtKB:P08254) PTPN6(UniProtKB:P29350) IL36A(UniProtKB:Q9UHA7) ZC3H15(UniProtKB:Q8WU90) STAT5A(UniProtKB:P42229) SOCS3(UniProtKB:O14543) STX1A(UniProtKB:Q16623) VAV1(UniProtKB:P15498) BATF(UniProtKB:Q16520) RPS27A(UniProtKB:P62979) IL6ST(UniProtKB:P40189) CRLF1(UniProtKB:O75462) IL26(UniProtKB:Q9NPH9) CRLF2(UniProtKB:Q9HC73) IL19(UniProtKB:Q9UHD0) CSF3(UniProtKB:P09919) FSCN1(UniProtKB:Q16658) IFNAR1(UniProtKB:P17181) ITGAM(UniProtKB:P11215) IRAK1(UniProtKB:P51617) CCR5(UniProtKB:P51681) STAT6(UniProtKB:P42226) CX3CL1(UniProtKB:P78423) IL10(UniProtKB:P22301) PLP2(UniProtKB:Q04941) DUOX2(UniProtKB:Q9NRD8) GREM2(UniProtKB:Q9H772) AKT1(UniProtKB:P31749) IFNA14(UniProtKB:P01570) STX3(UniProtKB:Q13277) PIK3CB(UniProtKB:P42338) STAT4(UniProtKB:Q14765) HMOX1(UniProtKB:P09601) CDKN1A(UniProtKB:P38936) NOS2(UniProtKB:P35228) IL17RD(UniProtKB:Q8NFM7) IL22(UniProtKB:Q9GZX6) LIFR(UniProtKB:P42702) CSF2(UniProtKB:P04141) CCND1(UniProtKB:P24385) SAA1(UniProtKB:P0DJI8) NANOG(UniProtKB:Q9H9S0) PIK3CA(UniProtKB:P42336) RAPGEF1(UniProtKB:Q13905) HSPA8(UniProtKB:P11142) KRAS(UniProtKB:P01116) IL2RG(UniProtKB:P31785) IL12B(UniProtKB:P29460) POMC(UniProtKB:P01189) IL36B(UniProtKB:Q9NZH7) SOCS5(UniProtKB:O75159) LRP8(UniProtKB:Q14114) OSMR(UniProtKB:Q99650) IFNGR2(UniProtKB:P38484) VCAM1(UniProtKB:P19320) ZNF675(UniProtKB:Q8TD23) CCL19(UniProtKB:Q99731) IL22RA1(UniProtKB:Q8N6P7) MUC1(UniProtKB:P15941) HCK(UniProtKB:P08631) STAT5B(UniProtKB:P51692) TNFRSF1A(UniProtKB:P19438) NDN(UniProtKB:Q99608) IL37(UniProtKB:Q9NZH6) STAT2(UniProtKB:P52630) IL20(UniProtKB:Q9NYY1) UBB(UniProtKB:P0CG47) PRTN3(UniProtKB:P24158) IFNL1(UniProtKB:Q8IU54) IFNA5(UniProtKB:P01569) IL11RA(UniProtKB:Q14626) PTGS2(UniProtKB:P35354) KLF6(UniProtKB:Q99612) IFNA10(UniProtKB:P01566) IGHG1(UniProtKB:P01857) IFNK(UniProtKB:Q9P0W0) SH2B2(UniProtKB:O14492) IL12A(UniProtKB:P29459) CRK(UniProtKB:P46108) S1PR1(UniProtKB:P21453) IL16(UniProtKB:Q14005) CTF1(UniProtKB:Q16619) ANXA1(UniProtKB:P04083) PTPN11(UniProtKB:Q06124) SOX2(UniProtKB:P48431) STX4(UniProtKB:Q12846) PTAFR(UniProtKB:P25105) RELA(UniProtKB:Q04206) FCER2(UniProtKB:P06734) LCN2(UniProtKB:P80188) FPR1(UniProtKB:P21462) CBL(UniProtKB:P22681) IL10RA(UniProtKB:Q13651) BAD(UniProtKB:Q92934) CXCL1(UniProtKB:P09341) IFNL3(UniProtKB:Q8IZI9) IL17F(UniProtKB:Q96PD4) IRAK4(UniProtKB:Q9NWZ3) BIRC5(UniProtKB:O15392) TWIST1(UniProtKB:Q15672) GATA3(UniProtKB:P23771) OPRM1(UniProtKB:P35372) IFNA17(UniProtKB:P01571) FER(UniProtKB:P16591) UBC(UniProtKB:P0CG48) |
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| label |
Cytokine-mediated Signaling Pathway |
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| MCID |
MC04808625 |
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| PMOID |
PMO:00063900 |
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| prefixIRI |
pmo:PMO_00063900 |
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| prefLabel |
Cytokine-mediated Signaling Pathway |
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| Synonym |
"cytokine and chemokine mediated signaling pathway" EXACT [] "cytokine mediated signalling pathway" EXACT [] |
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| Tree Number |
T10.1.26.1.33.23.24.24 T10.1.29.20.24.24 |
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| subClassOf |