PMO Precision Medicine Ontology

Last uploaded: December 16, 2020
Preferred Name

Extracellular Matrix
Synonyms
Definitions

"A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues." [GOC:BHF, GOC:mah, GOC:rph, NIF_Subcellular:nlx_subcell_20090513, PMID:21123617, PMID:28089324]

ID

http://www.phoc.org.cn/pmo/class/PMO_00054251

Database_Cross_Reference

GO:0031012

Definition

"A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues." [GOC:BHF, GOC:mah, GOC:rph, NIF_Subcellular:nlx_subcell_20090513, PMID:21123617, PMID:28089324]

Gene Annotation

VWA1(UniProtKB:Q6PCB0)

MMP15(UniProtKB:P51511)

TIMP1(UniProtKB:P01033)

COL4A4(UniProtKB:P53420)

PHOSPHO1(UniProtKB:Q8TCT1)

MEPE(UniProtKB:Q9NQ76)

ADAMTS13(UniProtKB:Q76LX8)

CYR61(UniProtKB:O00622)

EMILIN3(UniProtKB:Q9NT22)

VIT(UniProtKB:Q6UXI7)

MGP(UniProtKB:P08493)

FN1(UniProtKB:P02751)

PTX3(UniProtKB:P26022)

FBN3(UniProtKB:Q75N90)

POSTN(UniProtKB:Q15063)

MMP26(UniProtKB:Q9NRE1)

ECM2(UniProtKB:O94769)

TGFB1(UniProtKB:P01137)

COL6A6(UniProtKB:A6NMZ7)

MMP1(UniProtKB:P03956)

FLRT1(UniProtKB:Q9NZU1)

MMP17(UniProtKB:Q9ULZ9)

COL16A1(UniProtKB:Q07092)

COL23A1(UniProtKB:Q86Y22)

TFIP11(UniProtKB:Q9UBB9)

COL4A5(UniProtKB:P29400)

COLEC12(UniProtKB:Q5KU26)

CPN2(UniProtKB:P22792)

COL14A1(UniProtKB:Q05707)

ADAMTS3(UniProtKB:O15072)

TNN(UniProtKB:Q9UQP3)

LAMA1(UniProtKB:P25391)

ACAN(UniProtKB:P16112)

LRRTM4(UniProtKB:Q86VH4)

GFOD2(UniProtKB:Q3B7J2)

MMP28(UniProtKB:Q9H239)

MATN4(UniProtKB:O95460)

DMBT1(UniProtKB:Q9UGM3)

AMTN(UniProtKB:Q6UX39)

COL6A1(UniProtKB:P12109)

COL4A1(UniProtKB:P02462)

FBLN1(UniProtKB:P23142)

LOX(UniProtKB:P28300)

LRIG3(UniProtKB:Q6UXM1)

COL18A1(UniProtKB:P39060)

COL3A1(UniProtKB:P02461)

TIMP3(UniProtKB:P35625)

RELN(UniProtKB:P78509)

WNT4(UniProtKB:P56705)

LINGO4(UniProtKB:Q6UY18)

WNT6(UniProtKB:Q9Y6F9)

VWA2(UniProtKB:Q5GFL6)

TNFRSF11B(UniProtKB:O00300)

KERA(UniProtKB:O60938)

SPON1(UniProtKB:Q9HCB6)

TGFBR3(UniProtKB:Q03167)

FMOD(UniProtKB:Q06828)

COMP(UniProtKB:P49747)

MMP10(UniProtKB:P09238)

RTN4RL1(UniProtKB:Q86UN2)

COL27A1(UniProtKB:Q8IZC6)

IGFALS(UniProtKB:P35858)

VEGFA(UniProtKB:P15692)

DSPP(UniProtKB:Q9NZW4)

MMP20(UniProtKB:O60882)

ECM1(UniProtKB:Q16610)

FLRT3(UniProtKB:Q9NZU0)

COL5A1(UniProtKB:P20908)

LRRC3B(UniProtKB:Q96PB8)

LRRC24(UniProtKB:Q50LG9)

WISP1(UniProtKB:O95388)

MMP14(UniProtKB:P50281)

CHAD(UniProtKB:O15335)

MMP7(UniProtKB:P09237)

COL13A1(UniProtKB:Q5TAT6)

MMP24(UniProtKB:Q9Y5R2)

LTBP2(UniProtKB:Q14767)

FBLN5(UniProtKB:Q9UBX5)

DMP1(UniProtKB:Q13316)

EMILIN2(UniProtKB:Q9BXX0)

TIMP2(UniProtKB:P16035)

PRSS2(UniProtKB:P07478)

FGF1(UniProtKB:P05230)

CHADL(UniProtKB:Q6NUI6)

PI3(UniProtKB:P19957)

LRRC17(UniProtKB:Q8N6Y2)

ADAMTS9(UniProtKB:Q9P2N4)

COL4A6(UniProtKB:Q14031)

COL28A1(UniProtKB:Q2UY09)

TFPI2(UniProtKB:P48307)

IMPG2(UniProtKB:Q9BZV3)

COL1A2(UniProtKB:P08123)

ASPN(UniProtKB:Q9BXN1)

COL17A1(UniProtKB:Q9UMD9)

VASN(UniProtKB:Q6EMK4)

SCARA3(UniProtKB:Q6AZY7)

GPLD1(UniProtKB:P80108)

COCH(UniProtKB:O43405)

LUM(UniProtKB:P51884)

IMPG1(UniProtKB:Q17R60)

PRELP(UniProtKB:P51888)

WNT3(UniProtKB:P56703)

COL4A3(UniProtKB:Q01955)

UCMA(UniProtKB:Q8WVF2)

APOE(UniProtKB:P02649)

CD180(UniProtKB:Q99467)

MMP25(UniProtKB:Q9NPA2)

LRIG2(UniProtKB:O94898)

SERAC1(UniProtKB:Q96JX3)

COL15A1(UniProtKB:P39059)

MATN1(UniProtKB:P21941)

SPOCK2(UniProtKB:Q92563)

WNT7A(UniProtKB:O00755)

CCN3(UniProtKB:P48745)

SPON2(UniProtKB:Q9BUD6)

MMP13(UniProtKB:P45452)

VCAN(UniProtKB:P13611)

ADAMTS5(UniProtKB:Q9UNA0)

COL1A1(UniProtKB:P02452)

MATN3(UniProtKB:O15232)

WISP2(UniProtKB:O76076)

CRISP3(UniProtKB:P54108)

CCBE1(UniProtKB:Q6UXH8)

MMP19(UniProtKB:Q99542)

LRRN1(UniProtKB:Q6UXK5)

ANOS1(UniProtKB:P23352)

HAPLN2(UniProtKB:Q9GZV7)

TIMP4(UniProtKB:Q99727)

COL24A1(UniProtKB:Q17RW2)

MATN2(UniProtKB:O00339)

TNXB(UniProtKB:P22105)

ELFN2(UniProtKB:Q5R3F8)

COL9A2(UniProtKB:Q14055)

HPSE2(UniProtKB:Q8WWQ2)

MMP3(UniProtKB:P08254)

COL5A3(UniProtKB:P25940)

COL22A1(UniProtKB:Q8NFW1)

COL2A1(UniProtKB:P02458)

MBL2(UniProtKB:P11226)

TGFBI(UniProtKB:Q15582)

FBLN2(UniProtKB:P98095)

COL6A2(UniProtKB:P12110)

TECTB(UniProtKB:Q96PL2)

MMRN2(UniProtKB:Q9H8L6)

CD248(UniProtKB:Q9HCU0)

CTGF(UniProtKB:P29279)

HMCN2(UniProtKB:Q8NDA2)

BGN(UniProtKB:P21810)

DGCR6(UniProtKB:Q14129)

ADAMTSL2(UniProtKB:Q86TH1)

FBN2(UniProtKB:P35556)

LRRC15(UniProtKB:Q8TF66)

ELFN1(UniProtKB:P0C7U0)

CHI3L1(UniProtKB:P36222)

LRRC3C(UniProtKB:A6NJW4)

MMRN1(UniProtKB:Q13201)

CRISPLD2(UniProtKB:Q9H0B8)

NDNF(UniProtKB:Q8TB73)

COL26A1(UniProtKB:Q96A83)

ADAMTSL5(UniProtKB:Q6ZMM2)

I6L893(UniProtKB:I6L893)

COL9A3(UniProtKB:Q14050)

COL5A2(UniProtKB:P05997)

ELN(UniProtKB:P15502)

HSD17B12(UniProtKB:Q53GQ0)

FLRT2(UniProtKB:O43155)

BCAN(UniProtKB:Q96GW7)

COLQ(UniProtKB:Q9Y215)

LRRN2(UniProtKB:O75325)

GP1BA(UniProtKB:P07359)

RTN4RL2(UniProtKB:Q86UN3)

OPTC(UniProtKB:Q9UBM4)

NYX(UniProtKB:Q9GZU5)

HAPLN1(UniProtKB:P10915)

LRRC32(UniProtKB:Q14392)

HPSE(UniProtKB:Q9Y251)

MMP12(UniProtKB:P39900)

ALPL(UniProtKB:P05186)

LRIG1(UniProtKB:Q96JA1)

HAPLN3(UniProtKB:Q96S86)

LTBP4(UniProtKB:Q8N2S1)

LINGO2(UniProtKB:Q7L985)

LTBP1(UniProtKB:Q14766)

LRRTM1(UniProtKB:Q86UE6)

IHH(UniProtKB:Q14623)

THBS1(UniProtKB:P07996)

COL10A1(UniProtKB:Q03692)

COL11A1(UniProtKB:P12107)

OC90(UniProtKB:Q02509)

COL8A1(UniProtKB:P27658)

R4GN57(UniProtKB:R4GN57)

EMILIN1(UniProtKB:Q9Y6C2)

CCN6(UniProtKB:O95389)

GPC1(UniProtKB:P35052)

MUC4(UniProtKB:Q99102)

COL6A3(UniProtKB:P12111)

HAPLN4(UniProtKB:Q86UW8)

COL21A1(UniProtKB:Q96P44)

MMP27(UniProtKB:Q9H306)

LAMC3(UniProtKB:Q9Y6N6)

NCAN(UniProtKB:O14594)

ENAM(UniProtKB:Q9NRM1)

COL25A1(UniProtKB:Q9BXS0)

TRIL(UniProtKB:Q7L0X0)

FBN1(UniProtKB:P35555)

COL19A1(UniProtKB:Q14993)

COL11A2(UniProtKB:P13942)

MMP11(UniProtKB:P24347)

COL4A2(UniProtKB:P08572)

OLFML2A(UniProtKB:Q68BL7)

LINGO1(UniProtKB:Q96FE5)

COL7A1(UniProtKB:Q02388)

COL20A1(UniProtKB:Q9P218)

MMP21(UniProtKB:Q8N119)

MMP23B(UniProtKB:O75900)

COL8A2(UniProtKB:P25067)

LRRTM3(UniProtKB:Q86VH5)

EMID1(UniProtKB:Q96A84)

GLG1(UniProtKB:Q92896)

MMP16(UniProtKB:P51512)

OTOL1(UniProtKB:A6NHN0)

LINGO3(UniProtKB:P0C6S8)

COL9A1(UniProtKB:P20849)

EFEMP1(UniProtKB:Q12805)

TLR3(UniProtKB:O15455)

COL12A1(UniProtKB:Q99715)

WNT11(UniProtKB:O96014)

label

Extracellular Matrix

MCID

MC04787613

PMOID

PMO:00054251

prefixIRI

pmo:PMO_00054251

prefLabel

Extracellular Matrix

Synonym

"proteinaceous extracellular matrix" EXACT []

"matrisome" NARROW []

Tree Number

T10.3.20.35

subClassOf

http://www.phoc.org.cn/pmo/class/PMO_00054249

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/GO_0031012 UPHENO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#A11.284.295.310 RH-MESH LOOM
http://cbo.biocomplexity.indiana.edu/svn/cbo/trunk/CBO_1_1_2.owl#ExtraCellularMatrix CBO LOOM
http://purl.bioontology.org/ontology/MESH/D005109 MESH LOOM
http://purl.obolibrary.org/obo/XAO_0004027 XPO LOOM
http://purl.obolibrary.org/obo/XAO_0004027 XAO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#4796 OCHV LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D005109 RH-MESH LOOM
http://purl.org/obo/owl/GO#GO_0031012 BIOMODELS LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Extracellular_Matrix CSEO LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C13232 NCIT LOOM
http://purl.obolibrary.org/obo/OMIT_0006333 OMIT LOOM
http://purl.obolibrary.org/obo/VSAO_0000022 VSAO LOOM
http://purl.obolibrary.org/obo/VSAO_0000022 TAO LOOM
http://purl.obolibrary.org/obo/NCIT_C13232 BERO LOOM
http://www.projecthalo.com/aura#Extra-Cellular-Matrix AURA LOOM
http://uri.neuinfo.org/nif/nifstd/nlx_subcell_20090513 NIFSTD LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0015350 OCHV LOOM
http://purl.obolibrary.org/obo/LMHA_00168 LUNGMAP-HUMAN LOOM
http://purl.obolibrary.org/obo/EMAPA_38029 EMAPA LOOM
http://purl.obolibrary.org/obo/LMMA_00168 LUNGMAP-MOUSE LOOM
http://id.nlm.nih.gov/mesh/D005109 MDM LOOM
http://regenbase.org/ontology#RB_0000182 RB LOOM
http://purl.jp/bio/4/id/200906094282795346 IOBC LOOM
http://localhost/plosthes.2017-1#3405 PLOSTHES LOOM
http://purl.obolibrary.org/obo/MESH_D005109 BERO LOOM
http://purl.obolibrary.org/obo/ECAO_0107590 ECAO LOOM
http://purl.obolibrary.org/obo/GO_0031012 NIGO LOOM
http://purl.obolibrary.org/obo/GO_0031012 CL LOOM
http://purl.obolibrary.org/obo/GO_0031012 GO-EXT LOOM
http://purl.obolibrary.org/obo/GO_0031012 UBERON LOOM
http://purl.obolibrary.org/obo/GO_0031012 CLO LOOM
http://purl.obolibrary.org/obo/GO_0031012 PLANP LOOM
http://purl.obolibrary.org/obo/GO_0031012 GCBO LOOM
http://purl.obolibrary.org/obo/GO_0031012 CCONT LOOM
http://purl.obolibrary.org/obo/GO_0031012 FOVT LOOM
http://purl.obolibrary.org/obo/GO_0031012 HOIP LOOM
http://purl.obolibrary.org/obo/GO_0031012 CCO LOOM
http://purl.obolibrary.org/obo/GO_0031012 REXO LOOM
http://purl.obolibrary.org/obo/GO_0031012 RBO LOOM
http://purl.obolibrary.org/obo/GO_0031012 GEXO LOOM
http://purl.obolibrary.org/obo/GO_0031012 EFO LOOM
http://purl.obolibrary.org/obo/GO_0031012 XPO LOOM
http://purl.obolibrary.org/obo/GO_0031012 PHAGE LOOM
http://purl.obolibrary.org/obo/GO_0031012 PCL LOOM
http://purl.obolibrary.org/obo/GO_0031012 PATO LOOM
http://purl.obolibrary.org/obo/GO_0031012 NIFDYS LOOM
http://purl.obolibrary.org/obo/GO_0031012 CTENO LOOM
http://purl.obolibrary.org/obo/GO_0031012 GO-PLUS LOOM
http://purl.obolibrary.org/obo/GO_0031012 BERO LOOM
http://purl.obolibrary.org/obo/GO_0031012 EFO LOOM
http://purl.obolibrary.org/obo/GO_0031012 NBO LOOM
http://purl.obolibrary.org/obo/GO_0031012 HHEAR LOOM
http://purl.obolibrary.org/obo/GO_0031012 TXPO LOOM
http://purl.obolibrary.org/obo/GO_0031012 NIFSTD LOOM
http://purl.obolibrary.org/obo/GO_0031012 ECAO LOOM
http://purl.obolibrary.org/obo/GO_0031012 KTAO LOOM
http://purl.obolibrary.org/obo/GO_0031012 REGN_GO LOOM
http://purl.obolibrary.org/obo/GO_0031012 RETO LOOM
http://purl.obolibrary.org/obo/GO_0031012 MAXO LOOM
http://purl.obolibrary.org/obo/GO_0031012 GO LOOM
http://purl.obolibrary.org/obo/GO_0031012 ZP LOOM
http://purl.obolibrary.org/obo/GO_0031012 ODNAE LOOM
http://purl.obolibrary.org/obo/GO_0031012 AISM LOOM
http://purl.obolibrary.org/obo/GO_0031012 NMDCO LOOM
http://purl.obolibrary.org/obo/GO_0031012 OBA LOOM
http://purl.obolibrary.org/obo/ID_0000202 BCTEO LOOM
http://ontology.neuinfo.org/NIF/BiomaterialEntities/NIF-Subcellular.owl#nlx_subcell_20090513 NIFSUBCELL LOOM
http://purl.obolibrary.org/obo/PLANA_0002037 PLANA LOOM
http://purl.obolibrary.org/obo/PLANA_0002037 PLANP LOOM
http://purl.bioontology.org/ontology/CSP/0595-5294 CRISP LOOM