Preferred Name |
Nephroblastoma |
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ID |
http://localhost/plosthes.2017-1#8213 |
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alpha |
Nephroblastoma |
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prefLabel |
Nephroblastoma |
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Previous_Classification |
60.300.60.40.30^Nephroblastoma |
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scopeNote |
Wilms' tumor is a rare kidney cancer that primarily affects children. Also known as nephroblastoma, Wilms' tumor is the most common cancer of the kidneys in children. Wilms' tumor most often affects children ages 3 to 4 and becomes much less common after age 5. Wilms' tumor most often occurs in just one kidney, though it can sometimes be found in both kidneys at the same time. Improvements in the diagnosis and treatment of Wilms' tumor have improved the prognosis for children with this disease. The outlook for most children with Wilms' tumor is very good. http://www.mayoclinic.org/diseases-conditions/wilms-tumor/basics/definition/con-20043492 Wilms' tumour is a type of kidney cancer that was named after Dr Max Wilms, who first described it. It's thought to come from very specialised cells in the embryo known as metanephric blastema. These cells are involved in the development of the child's kidneys while they're in the womb. The cells usually disappear at birth, but in many children with Wilms' tumour, cells called nephrogenic rests can still be found. http://www.macmillan.org.uk/Cancerinformation/Cancertypes/Childrenscancers/Typesofchildrenscancers/Wilmstumour.aspx Wilms tumor accounts for 95 percent of kidney and renal cancers in children under the age of 14. Also called “nephroblastoma,” Wilms tumor is a mass of cancer cells that grow in kidney tissue. This is a disease primarily of young children. At the time of diagnosis, most Wilms tumor patients are less than five years old. Clinical trials over the past 22 years have been associated with improved long-term survival rates for children with Wilms tumor. Quick facts Between 400-500 new cases of Wilms tumor are diagnosed each year in the U.S. About six percent of all cancers in children are Wilms tumor. Clinical trials over the past 22 years have been associated with improved long-term survival rates for children with Wilms tumor. The long-term survival has approached 90 percent for most patients, and 95 percent for those with the most favorable prognosis. Careful use of surgery and a combination chemotherapy and radiation therapy, where necessary, have produced these results. http://www.childrenscancer.org/main/wilms_tumor_nephroblastoma/ RD |
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Accepted |
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