Protein-ligand interaction ontology

Last uploaded: November 3, 2014
Preferred Name

efficacy
Synonyms
ID

http://www.semanticweb.org/ontologies/2010/3/Ontology1271664172453.owl#efficacy

isDefinedBy

Efficacy is the property that enables drugs to produce responses. It is convenient to differentiate the properties of drugs into two groups, those which cause them to associate with the receptors (affinity) and those that produce stimulus (Efficacy). This term is often used to characterize the level of maximal responses induced by agonists. In fact, not all agonists of a receptor are capable of inducing identical levels of maximal responses. Maximal response depends on the efficiency of receptor coupling, i.e., from the cascade of events, which, from the binding of the drug to the receptor, leads to the observed biological effect.

prefixIRI

Ontology1271664172453:efficacy

prefLabel

efficacy

Reference

http://www.chem.qmul.ac.uk/iupac/medchem/ah.html#e1

Synonym

efficacy efficacies

subClassOf

http://www.semanticweb.org/ontologies/2010/3/Ontology1271664172453.owl#Intrinsic_activity

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