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Pathogen Host Interaction Phenotype Ontology
| Preferred Name | verapamil | |
| Synonyms |
verapamilum verapamil verapamilo rac-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile Verapamil |
|
| Definitions |
A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_9948 |
|
| bearer of |
http://purl.obolibrary.org/obo/CHEBI_38070 http://purl.obolibrary.org/obo/CHEBI_77745 http://purl.obolibrary.org/obo/CHEBI_62872 http://purl.obolibrary.org/obo/CHEBI_35703 http://purl.obolibrary.org/obo/CHEBI_35620 http://purl.obolibrary.org/obo/CHEBI_77748 http://purl.obolibrary.org/obo/CHEBI_38215 http://purl.obolibrary.org/obo/CHEBI_35674 http://purl.obolibrary.org/obo/CHEBI_77747 |
|
| charge |
0
|
|
| database_cross_reference |
HMDB:HMDB0001850 PMID:19125880 PMID:26046259 PMID:12454681 DrugBank:DB00661 PMID:25331694 PMID:18093581 PMID:16545584 PMID:26553277 PMID:11975770 PMID:25650380 CAS:52-53-9 PMID:26567612 PMID:14681337 PMID:25968157 PMID:11389609 PMID:26504804 KEGG:C07188 PMID:17724247 PMID:24532601 PMID:8861548 PMID:24577794 PMID:11142488 KEGG:D02356 PMID:17525564 PMID:11454724 Wikipedia:Verapamil Reaxys:2825000 PMID:18337499 PMID:25297337 Beilstein:2825000
|
|
| formula |
C27H38N2O4
|
|
| has part | ||
| has role |
http://purl.obolibrary.org/obo/CHEBI_38070 http://purl.obolibrary.org/obo/CHEBI_77745 http://purl.obolibrary.org/obo/CHEBI_62872 http://purl.obolibrary.org/obo/CHEBI_35703 http://purl.obolibrary.org/obo/CHEBI_35620 http://purl.obolibrary.org/obo/CHEBI_77748 http://purl.obolibrary.org/obo/CHEBI_38215 http://purl.obolibrary.org/obo/CHEBI_35674 http://purl.obolibrary.org/obo/CHEBI_77747 |
|
| has_exact_synonym |
rac-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile Verapamil
|
|
| has_obo_namespace |
chebi_ontology
|
|
| has_related_synonym |
verapamilum verapamil verapamilo
|
|
| id |
CHEBI:9948
|
|
| in_subset | ||
| label |
verapamil
|
|
| mass |
454.60160
|
|
| monoisotopicmass |
454.28316
|
|
| notation |
CHEBI:9948
|
|
| prefLabel |
verapamil
|
|
| textual definition |
A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
|
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |