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The Prescription of Drugs Ontology
Preferred Name | Ribavirin | |
Synonyms |
ribavirinum 1-beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide 1-beta-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide RBV ribavirin ribavirina ribavirine 1-(beta-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide |
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Definitions |
A 1-ribosyltriazole that is the 1-ribofuranosyl derivative of 1,2,4-triazole-3-carboxamide. A synthetic guanosine analogue, it is an inhibitor of HCV polymerase and possesses a broad spectrum of activity against DNA and RNA viruses. |
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ID |
http://purl.obolibrary.org/obo/CHEBI_63580 |
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alternative term |
ribavirinum 1-beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide 1-beta-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide RBV ribavirin ribavirina ribavirine 1-(beta-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide
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bearer_of |
http://purl.obolibrary.org/obo/CHEBI_35441 http://purl.obolibrary.org/obo/CHEBI_149553 http://purl.obolibrary.org/obo/CHEBI_35221 |
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charge |
0
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database_cross_reference |
PMID:22156853 Reaxys:892462 CAS:36791-04-5 Beilstein:892462 KEGG:D00423 Wikipedia:Ribavirin PMID:22239498 DrugBank:DB00811 PMID:22158703 PMID:22220723 PMID:22212569 PMID:22212568 PMID:22212566 PMID:22212572 PMID:22212576 PMID:22212579 PMID:22239511 PMID:21827730 PMID:22052088 PMID:22052220 LINCS:LSM-5701 Drug_Central:2373 PMID:29438107
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formula |
C8H12N4O5
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has functional parent | ||
has role |
http://purl.obolibrary.org/obo/CHEBI_35441 http://purl.obolibrary.org/obo/CHEBI_149553 http://purl.obolibrary.org/obo/CHEBI_35221 |
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has_alternative_id |
CHEBI:8840
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has_exact_synonym |
1-(beta-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide
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has_obo_namespace |
chebi_ontology
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has_related_synonym |
ribavirinum 1-beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide 1-beta-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide RBV ribavirin ribavirina ribavirine
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has_RxCUI |
9344
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id |
CHEBI:63580
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in_subset | ||
inchi |
InChI=1S/C8H12N4O5/c9-6(16)7-10-2-12(11-7)8-5(15)4(14)3(1-13)17-8/h2-5,8,13-15H,1H2,(H2,9,16)/t3-,4-,5-,8-/m1/s1
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inchikey |
IWUCXVSUMQZMFG-AFCXAGJDSA-N
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label |
ribavirin Ribavirin
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mass |
244.20470
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monoisotopicmass |
244.08077
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notation |
CHEBI:63580
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prefixIRI |
CHEBI:63580
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prefLabel |
Ribavirin
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smiles |
NC(=O)c1ncn(n1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
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textual definition |
A 1-ribosyltriazole that is the 1-ribofuranosyl derivative of 1,2,4-triazole-3-carboxamide. A synthetic guanosine analogue, it is an inhibitor of HCV polymerase and possesses a broad spectrum of activity against DNA and RNA viruses.
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subClassOf |
http://purl.obolibrary.org/obo/CHEBI_140324 http://purl.obolibrary.org/obo/CHEBI_62733 |
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