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The Prescription of Drugs Ontology
| Preferred Name | disulfiram | |
| Synonyms |
N,N,N',N'-tetraethylthiuram disulfide 1,1'-dithiobis(N,N-diethylthioformamide) bis(diethylthiocarbamoyl) disulfide Tetraethylthiuram disulfide tetraethylthiuram disulfide tetraethylthiuram disulphide tetraethylthioperoxydicarbonic diamide Antabuse 1,1',1'',1'''-[disulfanediylbis(carbonothioylnitrilo)]tetraethane Disulfiram |
|
| Definitions |
An organic disulfide that results from the formal oxidative dimerisation of N,N-diethyldithiocarbamic acid. A multi-enzyme inhibitor that is used in alcohol aversion therapy and also exhibits anticancer properties. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_4659 |
|
| alternative term |
N,N,N',N'-tetraethylthiuram disulfide 1,1'-dithiobis(N,N-diethylthioformamide) bis(diethylthiocarbamoyl) disulfide Tetraethylthiuram disulfide tetraethylthiuram disulfide tetraethylthiuram disulphide tetraethylthioperoxydicarbonic diamide Antabuse 1,1',1'',1'''-[disulfanediylbis(carbonothioylnitrilo)]tetraethane Disulfiram
|
|
| bearer_of |
http://purl.obolibrary.org/obo/CHEBI_24127 http://purl.obolibrary.org/obo/CHEBI_35610 http://purl.obolibrary.org/obo/CHEBI_37733 http://purl.obolibrary.org/obo/CHEBI_50276 http://purl.obolibrary.org/obo/CHEBI_173085 http://purl.obolibrary.org/obo/CHEBI_68495 http://purl.obolibrary.org/obo/CHEBI_73240 http://purl.obolibrary.org/obo/CHEBI_35487 |
|
| charge |
0
|
|
| database_cross_reference |
DrugBank:DB00822 PMID:15709459 PMID:16880974 PMID:25777347 Wikipedia:Disulfiram PMID:26517513 PMID:17667894 KEGG:D00131 Drug_Central:928 Pesticides:disulfiram PMID:19720750 KEGG:C01692 PMID:26314552 PMID:26235918 PMID:16426571 PMID:8572926 PMID:10841824 PMID:25565438 PMID:26239994 PMID:25464072 PMID:32971817 PMID:17079463 PMID:14978246 PMID:25495604 PMID:21471244 PMID:26033731 PMID:33731397 PMID:16666414 PMID:32963852 PMID:34045896 PMID:16661923 CAS:97-77-8 PMID:17579916 PMID:31151194 PMID:25557293 PMID:25445071 PMID:25476326 PMID:26224731 PMID:26550292 PMID:11005259 PMID:18579431 PMID:34012274 PMID:24496638 PMID:19787200 MetaCyc:DISULFIRAM PMID:25657800 Reaxys:1712560 LINCS:LSM-5467 PMID:25133664 HMDB:HMDB0014960 PMID:8442800 PMID:15325261 PMID:11716515 PMID:19782464
|
|
| formula |
C10H20N2S4
|
|
| has role |
http://purl.obolibrary.org/obo/CHEBI_24127 http://purl.obolibrary.org/obo/CHEBI_35610 http://purl.obolibrary.org/obo/CHEBI_37733 http://purl.obolibrary.org/obo/CHEBI_50276 http://purl.obolibrary.org/obo/CHEBI_173085 http://purl.obolibrary.org/obo/CHEBI_68495 http://purl.obolibrary.org/obo/CHEBI_73240 http://purl.obolibrary.org/obo/CHEBI_35487 |
|
| has_exact_synonym |
1,1',1'',1'''-[disulfanediylbis(carbonothioylnitrilo)]tetraethane Disulfiram
|
|
| has_obo_namespace |
chebi_ontology
|
|
| has_related_synonym |
N,N,N',N'-tetraethylthiuram disulfide 1,1'-dithiobis(N,N-diethylthioformamide) bis(diethylthiocarbamoyl) disulfide Tetraethylthiuram disulfide tetraethylthiuram disulfide tetraethylthiuram disulphide tetraethylthioperoxydicarbonic diamide Antabuse
|
|
| has_RxCUI |
3554
|
|
| id |
CHEBI:4659
|
|
| in_subset | ||
| inchi |
InChI=1S/C10H20N2S4/c1-5-11(6-2)9(13)15-16-10(14)12(7-3)8-4/h5-8H2,1-4H3
|
|
| inchikey |
AUZONCFQVSMFAP-UHFFFAOYSA-N
|
|
| label |
Disulfiram disulfiram
|
|
| mass |
296.544
|
|
| monoisotopicmass |
296.05093
|
|
| notation |
CHEBI:4659
|
|
| prefixIRI |
CHEBI:4659
|
|
| prefLabel |
disulfiram
|
|
| smiles |
S(SC(N(CC)CC)=S)C(N(CC)CC)=S
|
|
| textual definition |
An organic disulfide that results from the formal oxidative dimerisation of N,N-diethyldithiocarbamic acid. A multi-enzyme inhibitor that is used in alcohol aversion therapy and also exhibits anticancer properties.
|
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
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