Preferred Name |
carbamazepine |
|
Synonyms |
5H-Dibenz(b,f)azepine-5-carboxamide |
|
Definitions |
A tricyclic compound chemically related to tricyclic antidepressants (TCA) with anticonvulsant and analgesic properties. Carbamazepine exerts its anticonvulsant activity by reducing polysynaptic responses and blocking post-tetanic potentiation. Its analgesic activity is not understood; however, carbamazepine is commonly used to treat pain associated with trigeminal neuralgia. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C341" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C341" NCI Thesaurus) |
|
ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000042418 |
|
altLabel |
5H-Dibenz(b,f)azepine-5-carboxamide Tegretol Epitol |
|
CAS Registry |
298-46-4 |
|
cui |
C0006949 C0700087 C0700667 |
|
definition |
A tricyclic compound chemically related to tricyclic antidepressants (TCA) with anticonvulsant and analgesic properties. Carbamazepine exerts its anticonvulsant activity by reducing polysynaptic responses and blocking post-tetanic potentiation. Its analgesic activity is not understood; however, carbamazepine is commonly used to treat pain associated with trigeminal neuralgia. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C341" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C341" NCI Thesaurus) |
|
Legacy PDQ ID |
5690 |
|
LT |
TRD |
|
NCI ID |
C341 |
|
notation |
CDR0000042418 |
|
NSC Code |
169864 |
|
ORIG STY |
Drug/agent |
|
prefLabel |
carbamazepine |
|
tui |
T109 T121 |