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Physician Data Query
Last uploaded:
August 28, 2024
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| Preferred Name | ketoprofen | |
| Synonyms |
Oruvail capisten propionic scid, 2-(3-benzoylphenyl)- benzeneacetic Acid, 3-benzoyl-alpha-methyl- dexketoprofen Orudis |
|
| Definitions |
A propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic effects. Ketoprofen inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. The resulting decrease in prostaglandin synthesis, by prostaglandin synthase, is responsible for the therapeutic effects of ibuprofen. Ketoprofen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation. |
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| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000743614 |
|
| altLabel |
Oruvail capisten propionic scid, 2-(3-benzoylphenyl)- benzeneacetic Acid, 3-benzoyl-alpha-methyl- dexketoprofen Orudis
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|
| CAS Registry |
22071-15-4
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|
| cui |
C0022635 C0700190 C0591927 C0772505
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| DATE FIRST PUBLISHED |
2012-12-03
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| Date last modified |
2017-02-01
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|
| definition |
A propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic effects. Ketoprofen inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. The resulting decrease in prostaglandin synthesis, by prostaglandin synthase, is responsible for the therapeutic effects of ibuprofen. Ketoprofen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation.
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|
| LT |
TRD
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|
| notation |
CDR0000743614
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| ORIG STY |
Drug/agent
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|
| prefLabel |
ketoprofen
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|
| tui |
T109 T121
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