loading...| Preferred Name | citalopram hydrobromide | |
| Synonyms |
Celexa (±)-1-(3-dimethylaminopropyl)-1- (4-fluorophenyl)-1,3 dihydroisobenzofuran-5-carbonitrile, HBr |
|
| Definitions |
The orally bioavailable hydrobromide salt of the racemic bicyclic phthalene derivative citalopram with antidepressant activity. As a selective serotonin reuptake inhibitor (SSRI), citalopram selectively inhibits the CNS neuronal reuptake of serotonin, thereby potentiating serotonergic activity in the central nervous system (CNS). This agent has minimal effects on the CNS neuronal reuptake of norepinephrine (NE) and dopamine (DA). Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C28932" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C28932" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000500063 |
|
| altLabel |
Celexa (±)-1-(3-dimethylaminopropyl)-1- (4-fluorophenyl)-1,3 dihydroisobenzofuran-5-carbonitrile, HBr |
|
| cui |
C0719199 C0724555 |
|
| DATE FIRST PUBLISHED |
2006-08-06 |
|
| definition |
The orally bioavailable hydrobromide salt of the racemic bicyclic phthalene derivative citalopram with antidepressant activity. As a selective serotonin reuptake inhibitor (SSRI), citalopram selectively inhibits the CNS neuronal reuptake of serotonin, thereby potentiating serotonergic activity in the central nervous system (CNS). This agent has minimal effects on the CNS neuronal reuptake of norepinephrine (NE) and dopamine (DA). Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C28932" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C28932" NCI Thesaurus) |
|
| LT |
TRD |
|
| NCI ID |
C28932 |
|
| notation |
CDR0000500063 |
|
| ORIG STY |
Drug/agent |
|
| prefLabel |
citalopram hydrobromide |
|
| tui |
T109 T121 |