loading...| Preferred Name |
childhood hepatoblastoma |
|
| Synonyms |
Hepatoblastoma |
|
| Definitions |
A malignant liver neoplasm that occurs almost exclusively in infants, although isolated cases in older children and adults have been reported. Grossly, hepatoblastoma is solid, well circumscribed, and more often solitary than multiple. Microscopically, most of the tumors are composed exclusively of immature hepatocytic elements. About a fourth of hepatoblastomas contain a stromal component that may be undifferentiated or develop into bone or cartilage. The treatment of choice for hepatoblastoma is surgical excision with adjuvant therapy. Liver transplantation is being increasingly used as well. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C3728" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C3728" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000043722 |
|
| altLabel |
Hepatoblastoma hepatoblastoma, childhood HBL pediatric hepatoblastoma Pediatric Embryonal Hepatoma |
|
| Associated genetic condition |
http://purl.bioontology.org/ontology/PDQ/CDR0000725435 |
|
| cui |
C0206624 |
|
| Date last modified |
2012-03-26 |
|
| definition |
A malignant liver neoplasm that occurs almost exclusively in infants, although isolated cases in older children and adults have been reported. Grossly, hepatoblastoma is solid, well circumscribed, and more often solitary than multiple. Microscopically, most of the tumors are composed exclusively of immature hepatocytic elements. About a fourth of hepatoblastomas contain a stromal component that may be undifferentiated or develop into bone or cartilage. The treatment of choice for hepatoblastoma is surgical excision with adjuvant therapy. Liver transplantation is being increasingly used as well. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C3728" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C3728" NCI Thesaurus) |
|
| Legacy PDQ ID |
970 |
|
| NCI ID |
C3728 |
|
| notation |
CDR0000043722 |
|
| ORIG STY |
Neoplasm diagnosis |
|
| prefLabel |
childhood hepatoblastoma |
|
| tui |
T191 |
|
| subClassOf |