Physician Data Query

Last uploaded: August 28, 2024
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Preferred Name

ciprofloxacin
Synonyms

CPFX

Cipro

1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic Acid
Definitions

A synthetic broad spectrum fluoroquinolone antibiotic. Ciprofloxacin binds to and inhibits bacterial DNA gyrase, an enzyme essential for DNA replication. This agent is more active against Gram-negative bacteria than Gram-positive bacteria. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C375" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C375" NCI Thesaurus)
ID

http://purl.bioontology.org/ontology/PDQ/CDR0000040784
altLabel

CPFX

Cipro

1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic Acid
CAS Registry

85721-33-1
Component of

http://purl.bioontology.org/ontology/PDQ/CDR0000429575

http://purl.bioontology.org/ontology/PDQ/CDR0000042812

http://purl.bioontology.org/ontology/PDQ/CDR0000041923

http://purl.bioontology.org/ontology/PDQ/CDR0000041921

http://purl.bioontology.org/ontology/PDQ/CDR0000306457

http://purl.bioontology.org/ontology/PDQ/CDR0000041870

http://purl.bioontology.org/ontology/PDQ/CDR0000042012

http://purl.bioontology.org/ontology/PDQ/CDR0000042011

http://purl.bioontology.org/ontology/PDQ/CDR0000043082

http://purl.bioontology.org/ontology/PDQ/CDR0000042811
cui

C0008809

C0701042
Date last modified

2006-07-31
definition

A synthetic broad spectrum fluoroquinolone antibiotic. Ciprofloxacin binds to and inhibits bacterial DNA gyrase, an enzyme essential for DNA replication. This agent is more active against Gram-negative bacteria than Gram-positive bacteria. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C375" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C375" NCI Thesaurus)
Legacy PDQ ID

3748
LT

TRD
NCI ID

C375
notation

CDR0000040784
ORIG STY

Drug/agent
prefLabel

ciprofloxacin
tui

T109

T121
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Mapping To Ontology Source
http://purl.bioontology.org/ontology/ATC/S01AE03 ATC CUI
http://purl.bioontology.org/ontology/RXNORM/203563 RXNORM CUI
http://purl.bioontology.org/ontology/MESH/D002939 MESH CUI
http://purl.bioontology.org/ontology/VANDF/4019307 VANDF CUI
http://purl.bioontology.org/ontology/NDFRT/N0000007046 NDFRT CUI
http://purl.bioontology.org/ontology/SCTSPA/7577004 SCTSPA CUI
http://purl.bioontology.org/ontology/ATC/S03AA07 ATC CUI
http://purl.bioontology.org/ontology/RXNORM/2551 RXNORM CUI
http://purl.bioontology.org/ontology/SNMI/C-55710 SNMI CUI
http://purl.bioontology.org/ontology/SNOMEDCT/372840008 SNOMEDCT CUI
http://purl.bioontology.org/ontology/ATC/J01MA02 ATC CUI
http://purl.bioontology.org/ontology/NDFRT/N0000147503 NDFRT CUI
http://purl.bioontology.org/ontology/SNOMEDCT/7577004 SNOMEDCT CUI
http://purl.bioontology.org/ontology/LNC/LP15380-6 LOINC CUI
http://purl.bioontology.org/ontology/LNC/MTHU004599 LOINC CUI
http://purl.bioontology.org/ontology/ATC/S02AA15 ATC CUI
http://purl.bioontology.org/ontology/MSHFRE/D002939 MSHFRE CUI
http://purl.bioontology.org/ontology/CSP/5004-0016 CRISP CUI
http://purl.bioontology.org/ontology/RCD/eg6.. RCD CUI
http://purl.bioontology.org/ontology/NDDF/002882 NDDF CUI
http://purl.bioontology.org/ontology/SCTSPA/372840008 SCTSPA CUI
http://purl.bioontology.org/ontology/MESH/D002939 MESH CUI
http://purl.bioontology.org/ontology/CSP/5004-0016 CRISP CUI
http://purl.obolibrary.org/obo/ARO_0000036 ARO LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 DRON LOOM
http://purl.bioontology.org/ontology/ATC/S01AE03 ATC LOOM
http://purl.obolibrary.org/obo/MESH_D002939 BERO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D002939 RH-MESH LOOM
http://www.drugbank.ca/drugs/DB00537 FTC LOOM
http://purl.jp/bio/4/id/200906033484858081 IOBC LOOM
https://github.com/sap218/coid/blob/master/coid.owl#COID_00891 COID LOOM
http://purl.bioontology.org/ontology/MESH/D002939 MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0008809 OCHV LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.438.810.835.322.186 RH-MESH LOOM
http://purl.bioontology.org/ontology/VANDF/4019307 VANDF LOOM
http://www.semanticweb.org/administrator/ontologies/2022/0/untitled-ontology-34#OWLClass44da7dc5_9998_41a0_a770_884d9406b2c0 WWECA LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C375 NCIT LOOM
http://purl.bioontology.org/ontology/ATC/S03AA07 ATC LOOM
http://www.phoc.org.cn/pmo/class/PMO_00017909 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/RXNORM/2551 RXNORM LOOM
http://purl.bioontology.org/ontology/SNMI/C-55710 SNMI LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372840008 SNOMEDCT LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#3001 OCHV LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 EUPATH LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 HOIP LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 TXPO LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 UPHENO LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 PHIPO LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 ECTO LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 MCO LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_100241 ODNAE LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000147503 ODAE LOOM
https://bioportal.bioontology.org/ontologies/STMSO#Ciprofloxacin STMSO LOOM
http://purl.bioontology.org/ontology/ATC/J01MA02 ATC LOOM
https://go.drugbank.com/drugs/DB00537 MDM LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147503 NDFRT LOOM
http://purl.obolibrary.org/obo/OMIT_0004256 OMIT LOOM
http://purl.bioontology.org/ontology/LNC/LP15380-6 LOINC LOOM
http://purl.jp/bio/10/gmo/GMO_002228 GMO LOOM
http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Ciprofloxacin SEPON LOOM
http://www.co-ode.org/ontologies/galen#Ciprofloxacin GALEN LOOM
http://purl.bioontology.org/ontology/LNC/MTHU004599 LOINC LOOM
http://purl.bioontology.org/ontology/ATC/S02AA15 ATC LOOM
http://purl.bioontology.org/ontology/CSP/5004-0016 CRISP LOOM
http://stirdf.jst.go.jp/id/200907004431328874 IOBC LOOM
http://purl.bioontology.org/ontology/NDDF/002882 NDDF LOOM
http://purl.obolibrary.org/obo/NCIT_C375 BERO LOOM