loading...| Preferred Name | retinol | |
| Synonyms |
3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)-nona-2,4,6,8-tetraen-1-ol 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol 3,7-dimethyl-9-(2,6, 6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol |
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| Definitions |
The fat soluble vitamin retinol. Vitamin A binds to and activates retinoid receptors (RARs), thereby inducing cell differentiation and apoptosis of some cancer cell types and inhibiting carcinogenesis. Vitamin A plays an essential role in many physiologic processes, including proper functioning of the retina, growth and differentiation of target tissues, proper functioning of the reproductive organs, and modulation of immune function. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C68302" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C68302" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000039735 |
|
| altLabel |
3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)-nona-2,4,6,8-tetraen-1-ol 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol 3,7-dimethyl-9-(2,6, 6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol |
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| CAS Registry |
68-26-8 11103-57-4 |
|
| Component of |
http://purl.bioontology.org/ontology/PDQ/CDR0000042821 |
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| cui |
C0087161 |
|
| Date last modified |
2017-11-03 |
|
| definition |
The fat soluble vitamin retinol. Vitamin A binds to and activates retinoid receptors (RARs), thereby inducing cell differentiation and apoptosis of some cancer cell types and inhibiting carcinogenesis. Vitamin A plays an essential role in many physiologic processes, including proper functioning of the retina, growth and differentiation of target tissues, proper functioning of the reproductive organs, and modulation of immune function. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C68302" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C68302" NCI Thesaurus) |
|
| Legacy PDQ ID |
2397 |
|
| NCI ID |
C68302 |
|
| notation |
CDR0000039735 |
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| ORIG STY |
Drug/agent |
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| prefLabel |
retinol |
|
| tui |
T109 T127 T121 |