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Physician Data Query
| Preferred Name | droperidol | |
| Synonyms |
Inapsine |
|
| Definitions |
A butyrophenone with anti-emetic, sedative and anti-anxiety properties. Although the exact mechanism through which droperidol exerts its effects is unknown, droperidol may block dopamine receptors in the chemoreceptor trigger zone (CTZ), which may lead to its anti-emetic effect. This agent may also bind to postsynaptic gamma-aminobutyric acid (GABA) receptors in the central nervous system (CNS), which increases the inhibitory effect of GABA and leads to sedative and anti-anxiety activities. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C458" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C458" NCI Thesaurus) |
|
| ID |
http://purl.bioontology.org/ontology/PDQ/CDR0000039227 |
|
| altLabel |
Inapsine
|
|
| CAS Registry |
548-73-2
|
|
| cui |
C0013136 C0699335
|
|
| definition |
A butyrophenone with anti-emetic, sedative and anti-anxiety properties. Although the exact mechanism through which droperidol exerts its effects is unknown, droperidol may block dopamine receptors in the chemoreceptor trigger zone (CTZ), which may lead to its anti-emetic effect. This agent may also bind to postsynaptic gamma-aminobutyric acid (GABA) receptors in the central nervous system (CNS), which increases the inhibitory effect of GABA and leads to sedative and anti-anxiety activities. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C458" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C458" NCI Thesaurus)
|
|
| Legacy PDQ ID |
1849
|
|
| LT |
TRD
|
|
| NCI ID |
C458
|
|
| notation |
CDR0000039227
|
|
| NSC Code |
169874
|
|
| ORIG STY |
Drug/agent
|
|
| prefLabel |
droperidol
|
|
| tui |
T109 T121
|
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
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