Physician Data Query

Last uploaded: August 28, 2024

Preferred Name	cytarabine
Synonyms	Erpalfa U-29920A HCl arabinofuranosylcytosine ARA-cell Aracytine aracytidine 1-.beta.-D-arabinofuranosyl-4-amino-2(1H)pyrimidinone 4-amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone WR-28453 cytosine arabinosine hydrochloride Cytarbel Alexan Aracytin .beta.-Cytosine arabinoside beta-cytosine arabinoside Arabine ARA-C 2(1H)-pyrimidinone, 4-amino-1.beta.-D-arabinofuranosyl- cytarabinum cytosine arabinoside Tarabine PFS 1.beta.-D-arabinofuranosylcytosine cytarabine hydrochloride 1-beta-D-arabinofuranosylcytosine Udicil Cytosar CHX-3311 Starasid U-19920 U 19920 cytosine-.beta.-arabinoside arabinosylcytosine
Definitions	An antimetabolite analogue of cytidine with a modified sugar moiety (arabinose instead of ribose). Cytarabine is converted to the triphosphate form within the cell and then competes with cytidine for incorporation into DNA. Because the arabinose sugar sterically hinders the rotation of the molecule within DNA, DNA replication ceases, specifically during the S phase of the cell cycle. This agent also inhibits DNA polymerase, resulting in a decrease in DNA replication and repair. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C408" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C408" NCI Thesaurus)
ID	http://purl.bioontology.org/ontology/PDQ/CDR0000039015
altLabel	Erpalfa U-29920A HCl arabinofuranosylcytosine ARA-cell Aracytine aracytidine 1-.beta.-D-arabinofuranosyl-4-amino-2(1H)pyrimidinone 4-amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone WR-28453 cytosine arabinosine hydrochloride Cytarbel Alexan Aracytin .beta.-Cytosine arabinoside beta-cytosine arabinoside Arabine ARA-C 2(1H)-pyrimidinone, 4-amino-1.beta.-D-arabinofuranosyl- cytarabinum cytosine arabinoside Tarabine PFS 1.beta.-D-arabinofuranosylcytosine cytarabine hydrochloride 1-beta-D-arabinofuranosylcytosine Udicil Cytosar CHX-3311 Starasid U-19920 U 19920 cytosine-.beta.-arabinoside arabinosylcytosine
CAS Registry	147-94-4
Component of	http://purl.bioontology.org/ontology/PDQ/CDR0000042970 http://purl.bioontology.org/ontology/PDQ/CDR0000040878 http://purl.bioontology.org/ontology/PDQ/CDR0000038978 http://purl.bioontology.org/ontology/PDQ/CDR0000042061 http://purl.bioontology.org/ontology/PDQ/CDR0000043002 http://purl.bioontology.org/ontology/PDQ/CDR0000040601 http://purl.bioontology.org/ontology/PDQ/CDR0000038522 http://purl.bioontology.org/ontology/PDQ/CDR0000042288 http://purl.bioontology.org/ontology/PDQ/CDR0000041034 http://purl.bioontology.org/ontology/PDQ/CDR0000041469 http://purl.bioontology.org/ontology/PDQ/CDR0000037960 http://purl.bioontology.org/ontology/PDQ/CDR0000424451 http://purl.bioontology.org/ontology/PDQ/CDR0000041118 http://purl.bioontology.org/ontology/PDQ/CDR0000043453 http://purl.bioontology.org/ontology/PDQ/CDR0000041784 http://purl.bioontology.org/ontology/PDQ/CDR0000039042 http://purl.bioontology.org/ontology/PDQ/CDR0000038578 http://purl.bioontology.org/ontology/PDQ/CDR0000039781 http://purl.bioontology.org/ontology/PDQ/CDR0000042030 http://purl.bioontology.org/ontology/PDQ/CDR0000041164 http://purl.bioontology.org/ontology/PDQ/CDR0000040156 http://purl.bioontology.org/ontology/PDQ/CDR0000039186 http://purl.bioontology.org/ontology/PDQ/CDR0000041314 http://purl.bioontology.org/ontology/PDQ/CDR0000037865 http://purl.bioontology.org/ontology/PDQ/CDR0000038701 http://purl.bioontology.org/ontology/PDQ/CDR0000039371 http://purl.bioontology.org/ontology/PDQ/CDR0000043039 http://purl.bioontology.org/ontology/PDQ/CDR0000038311 http://purl.bioontology.org/ontology/PDQ/CDR0000040507 http://purl.bioontology.org/ontology/PDQ/CDR0000037972 http://purl.bioontology.org/ontology/PDQ/CDR0000335130 http://purl.bioontology.org/ontology/PDQ/CDR0000039631 http://purl.bioontology.org/ontology/PDQ/CDR0000042128 http://purl.bioontology.org/ontology/PDQ/CDR0000037834 http://purl.bioontology.org/ontology/PDQ/CDR0000040644 http://purl.bioontology.org/ontology/PDQ/CDR0000041350 http://purl.bioontology.org/ontology/PDQ/CDR0000042824 http://purl.bioontology.org/ontology/PDQ/CDR0000039046 http://purl.bioontology.org/ontology/PDQ/CDR0000040942 http://purl.bioontology.org/ontology/PDQ/CDR0000038030 http://purl.bioontology.org/ontology/PDQ/CDR0000037927 http://purl.bioontology.org/ontology/PDQ/CDR0000041691 http://purl.bioontology.org/ontology/PDQ/CDR0000042410 http://purl.bioontology.org/ontology/PDQ/CDR0000041595 http://purl.bioontology.org/ontology/PDQ/CDR0000355734 http://purl.bioontology.org/ontology/PDQ/CDR0000038662 http://purl.bioontology.org/ontology/PDQ/CDR0000040053 http://purl.bioontology.org/ontology/PDQ/CDR0000039041 http://purl.bioontology.org/ontology/PDQ/CDR0000042703 http://purl.bioontology.org/ontology/PDQ/CDR0000038700 http://purl.bioontology.org/ontology/PDQ/CDR0000041032 http://purl.bioontology.org/ontology/PDQ/CDR0000042015 http://purl.bioontology.org/ontology/PDQ/CDR0000344418 http://purl.bioontology.org/ontology/PDQ/CDR0000041229 http://purl.bioontology.org/ontology/PDQ/CDR0000041488 http://purl.bioontology.org/ontology/PDQ/CDR0000269068 http://purl.bioontology.org/ontology/PDQ/CDR0000039037 http://purl.bioontology.org/ontology/PDQ/CDR0000042407 http://purl.bioontology.org/ontology/PDQ/CDR0000040149 http://purl.bioontology.org/ontology/PDQ/CDR0000042398 http://purl.bioontology.org/ontology/PDQ/CDR0000039709 http://purl.bioontology.org/ontology/PDQ/CDR0000041831 http://purl.bioontology.org/ontology/PDQ/CDR0000299571 http://purl.bioontology.org/ontology/PDQ/CDR0000039603 http://purl.bioontology.org/ontology/PDQ/CDR0000038398 http://purl.bioontology.org/ontology/PDQ/CDR0000416130 http://purl.bioontology.org/ontology/PDQ/CDR0000037843 http://purl.bioontology.org/ontology/PDQ/CDR0000331877 http://purl.bioontology.org/ontology/PDQ/CDR0000042027 http://purl.bioontology.org/ontology/PDQ/CDR0000041637 http://purl.bioontology.org/ontology/PDQ/CDR0000042411 http://purl.bioontology.org/ontology/PDQ/CDR0000042942 http://purl.bioontology.org/ontology/PDQ/CDR0000038310 http://purl.bioontology.org/ontology/PDQ/CDR0000391015 http://purl.bioontology.org/ontology/PDQ/CDR0000038427 http://purl.bioontology.org/ontology/PDQ/CDR0000039095 http://purl.bioontology.org/ontology/PDQ/CDR0000039312 http://purl.bioontology.org/ontology/PDQ/CDR0000041582 http://purl.bioontology.org/ontology/PDQ/CDR0000039689 http://purl.bioontology.org/ontology/PDQ/CDR0000043397 http://purl.bioontology.org/ontology/PDQ/CDR0000041812 http://purl.bioontology.org/ontology/PDQ/CDR0000039420 http://purl.bioontology.org/ontology/PDQ/CDR0000039637 http://purl.bioontology.org/ontology/PDQ/CDR0000040161 http://purl.bioontology.org/ontology/PDQ/CDR0000043398 http://purl.bioontology.org/ontology/PDQ/CDR0000038879 http://purl.bioontology.org/ontology/PDQ/CDR0000041789 http://purl.bioontology.org/ontology/PDQ/CDR0000038872 http://purl.bioontology.org/ontology/PDQ/CDR0000043323 http://purl.bioontology.org/ontology/PDQ/CDR0000042248 http://purl.bioontology.org/ontology/PDQ/CDR0000039460 http://purl.bioontology.org/ontology/PDQ/CDR0000350091 http://purl.bioontology.org/ontology/PDQ/CDR0000041111 http://purl.bioontology.org/ontology/PDQ/CDR0000043399 http://purl.bioontology.org/ontology/PDQ/CDR0000322250 http://purl.bioontology.org/ontology/PDQ/CDR0000043402 http://purl.bioontology.org/ontology/PDQ/CDR0000038017 http://purl.bioontology.org/ontology/PDQ/CDR0000315408 http://purl.bioontology.org/ontology/PDQ/CDR0000042040 http://purl.bioontology.org/ontology/PDQ/CDR0000040215 http://purl.bioontology.org/ontology/PDQ/CDR0000040974 http://purl.bioontology.org/ontology/PDQ/CDR0000353152 http://purl.bioontology.org/ontology/PDQ/CDR0000409579 http://purl.bioontology.org/ontology/PDQ/CDR0000040958 http://purl.bioontology.org/ontology/PDQ/CDR0000038292 http://purl.bioontology.org/ontology/PDQ/CDR0000042244 http://purl.bioontology.org/ontology/PDQ/CDR0000043262 http://purl.bioontology.org/ontology/PDQ/CDR0000041624 http://purl.bioontology.org/ontology/PDQ/CDR0000043269 http://purl.bioontology.org/ontology/PDQ/CDR0000039694 http://purl.bioontology.org/ontology/PDQ/CDR0000042392 http://purl.bioontology.org/ontology/PDQ/CDR0000038891 http://purl.bioontology.org/ontology/PDQ/CDR0000042173 http://purl.bioontology.org/ontology/PDQ/CDR0000039529 http://purl.bioontology.org/ontology/PDQ/CDR0000040959 http://purl.bioontology.org/ontology/PDQ/CDR0000041609 http://purl.bioontology.org/ontology/PDQ/CDR0000041040 http://purl.bioontology.org/ontology/PDQ/CDR0000041230 http://purl.bioontology.org/ontology/PDQ/CDR0000041312 http://purl.bioontology.org/ontology/PDQ/CDR0000037826 http://purl.bioontology.org/ontology/PDQ/CDR0000043240 http://purl.bioontology.org/ontology/PDQ/CDR0000306480 http://purl.bioontology.org/ontology/PDQ/CDR0000042062 http://purl.bioontology.org/ontology/PDQ/CDR0000042887 http://purl.bioontology.org/ontology/PDQ/CDR0000041737 http://purl.bioontology.org/ontology/PDQ/CDR0000039044 http://purl.bioontology.org/ontology/PDQ/CDR0000039776 http://purl.bioontology.org/ontology/PDQ/CDR0000038693 http://purl.bioontology.org/ontology/PDQ/CDR0000038971 http://purl.bioontology.org/ontology/PDQ/CDR0000258744 http://purl.bioontology.org/ontology/PDQ/CDR0000039692 http://purl.bioontology.org/ontology/PDQ/CDR0000390236 http://purl.bioontology.org/ontology/PDQ/CDR0000039818 http://purl.bioontology.org/ontology/PDQ/CDR0000041149 http://purl.bioontology.org/ontology/PDQ/CDR0000041962 http://purl.bioontology.org/ontology/PDQ/CDR0000039537 http://purl.bioontology.org/ontology/PDQ/CDR0000257882 http://purl.bioontology.org/ontology/PDQ/CDR0000391013 http://purl.bioontology.org/ontology/PDQ/CDR0000040891 http://purl.bioontology.org/ontology/PDQ/CDR0000038732 http://purl.bioontology.org/ontology/PDQ/CDR0000298997 http://purl.bioontology.org/ontology/PDQ/CDR0000039038 http://purl.bioontology.org/ontology/PDQ/CDR0000037970 http://purl.bioontology.org/ontology/PDQ/CDR0000041152 http://purl.bioontology.org/ontology/PDQ/CDR0000037999 http://purl.bioontology.org/ontology/PDQ/CDR0000041373 http://purl.bioontology.org/ontology/PDQ/CDR0000038733 http://purl.bioontology.org/ontology/PDQ/CDR0000344423 http://purl.bioontology.org/ontology/PDQ/CDR0000041297 http://purl.bioontology.org/ontology/PDQ/CDR0000043359 http://purl.bioontology.org/ontology/PDQ/CDR0000361547 http://purl.bioontology.org/ontology/PDQ/CDR0000038855 http://purl.bioontology.org/ontology/PDQ/CDR0000040123 http://purl.bioontology.org/ontology/PDQ/CDR0000041203 http://purl.bioontology.org/ontology/PDQ/CDR0000041966 http://purl.bioontology.org/ontology/PDQ/CDR0000357718 http://purl.bioontology.org/ontology/PDQ/CDR0000042202 http://purl.bioontology.org/ontology/PDQ/CDR0000040328 http://purl.bioontology.org/ontology/PDQ/CDR0000038326 http://purl.bioontology.org/ontology/PDQ/CDR0000039110 http://purl.bioontology.org/ontology/PDQ/CDR0000347069 http://purl.bioontology.org/ontology/PDQ/CDR0000041733 http://purl.bioontology.org/ontology/PDQ/CDR0000040876 http://purl.bioontology.org/ontology/PDQ/CDR0000042172 http://purl.bioontology.org/ontology/PDQ/CDR0000041150 http://purl.bioontology.org/ontology/PDQ/CDR0000041995 http://purl.bioontology.org/ontology/PDQ/CDR0000041682 http://purl.bioontology.org/ontology/PDQ/CDR0000041219 http://purl.bioontology.org/ontology/PDQ/CDR0000041931 http://purl.bioontology.org/ontology/PDQ/CDR0000038285 http://purl.bioontology.org/ontology/PDQ/CDR0000038731 http://purl.bioontology.org/ontology/PDQ/CDR0000041782 http://purl.bioontology.org/ontology/PDQ/CDR0000042362 http://purl.bioontology.org/ontology/PDQ/CDR0000039353 http://purl.bioontology.org/ontology/PDQ/CDR0000043330 http://purl.bioontology.org/ontology/PDQ/CDR0000042644 http://purl.bioontology.org/ontology/PDQ/CDR0000042997 http://purl.bioontology.org/ontology/PDQ/CDR0000039066 http://purl.bioontology.org/ontology/PDQ/CDR0000344407 http://purl.bioontology.org/ontology/PDQ/CDR0000393428 http://purl.bioontology.org/ontology/PDQ/CDR0000043681 http://purl.bioontology.org/ontology/PDQ/CDR0000041073 http://purl.bioontology.org/ontology/PDQ/CDR0000361540 http://purl.bioontology.org/ontology/PDQ/CDR0000040082 http://purl.bioontology.org/ontology/PDQ/CDR0000041311 http://purl.bioontology.org/ontology/PDQ/CDR0000039581 http://purl.bioontology.org/ontology/PDQ/CDR0000354250 http://purl.bioontology.org/ontology/PDQ/CDR0000041374 http://purl.bioontology.org/ontology/PDQ/CDR0000041783 http://purl.bioontology.org/ontology/PDQ/CDR0000038287 http://purl.bioontology.org/ontology/PDQ/CDR0000041726 http://purl.bioontology.org/ontology/PDQ/CDR0000040956 http://purl.bioontology.org/ontology/PDQ/CDR0000043268 http://purl.bioontology.org/ontology/PDQ/CDR0000041934 http://purl.bioontology.org/ontology/PDQ/CDR0000038888 http://purl.bioontology.org/ontology/PDQ/CDR0000042031 http://purl.bioontology.org/ontology/PDQ/CDR0000038291 http://purl.bioontology.org/ontology/PDQ/CDR0000042294 http://purl.bioontology.org/ontology/PDQ/CDR0000038429 http://purl.bioontology.org/ontology/PDQ/CDR0000038374 http://purl.bioontology.org/ontology/PDQ/CDR0000042283 http://purl.bioontology.org/ontology/PDQ/CDR0000043307 http://purl.bioontology.org/ontology/PDQ/CDR0000039111 http://purl.bioontology.org/ontology/PDQ/CDR0000038876 http://purl.bioontology.org/ontology/PDQ/CDR0000039624 http://purl.bioontology.org/ontology/PDQ/CDR0000039565 http://purl.bioontology.org/ontology/PDQ/CDR0000038272 http://purl.bioontology.org/ontology/PDQ/CDR0000043403 http://purl.bioontology.org/ontology/PDQ/CDR0000041754 http://purl.bioontology.org/ontology/PDQ/CDR0000041735 http://purl.bioontology.org/ontology/PDQ/CDR0000040944 http://purl.bioontology.org/ontology/PDQ/CDR0000039634 http://purl.bioontology.org/ontology/PDQ/CDR0000040412 http://purl.bioontology.org/ontology/PDQ/CDR0000041490 http://purl.bioontology.org/ontology/PDQ/CDR0000041640 http://purl.bioontology.org/ontology/PDQ/CDR0000038523 http://purl.bioontology.org/ontology/PDQ/CDR0000043242 http://purl.bioontology.org/ontology/PDQ/CDR0000040064 http://purl.bioontology.org/ontology/PDQ/CDR0000038307 http://purl.bioontology.org/ontology/PDQ/CDR0000042960 http://purl.bioontology.org/ontology/PDQ/CDR0000043298 http://purl.bioontology.org/ontology/PDQ/CDR0000037925 http://purl.bioontology.org/ontology/PDQ/CDR0000038979 http://purl.bioontology.org/ontology/PDQ/CDR0000041278 http://purl.bioontology.org/ontology/PDQ/CDR0000039562 http://purl.bioontology.org/ontology/PDQ/CDR0000040838 http://purl.bioontology.org/ontology/PDQ/CDR0000039068 http://purl.bioontology.org/ontology/PDQ/CDR0000042016 http://purl.bioontology.org/ontology/PDQ/CDR0000041033 http://purl.bioontology.org/ontology/PDQ/CDR0000042281 http://purl.bioontology.org/ontology/PDQ/CDR0000038840 http://purl.bioontology.org/ontology/PDQ/CDR0000039349 http://purl.bioontology.org/ontology/PDQ/CDR0000038519 http://purl.bioontology.org/ontology/PDQ/CDR0000039695 http://purl.bioontology.org/ontology/PDQ/CDR0000038373 http://purl.bioontology.org/ontology/PDQ/CDR0000043125 http://purl.bioontology.org/ontology/PDQ/CDR0000042424 http://purl.bioontology.org/ontology/PDQ/CDR0000042448 http://purl.bioontology.org/ontology/PDQ/CDR0000039327 http://purl.bioontology.org/ontology/PDQ/CDR0000043404 http://purl.bioontology.org/ontology/PDQ/CDR0000040877 http://purl.bioontology.org/ontology/PDQ/CDR0000269679 http://purl.bioontology.org/ontology/PDQ/CDR0000042122 http://purl.bioontology.org/ontology/PDQ/CDR0000042123 http://purl.bioontology.org/ontology/PDQ/CDR0000041720 http://purl.bioontology.org/ontology/PDQ/CDR0000041955 http://purl.bioontology.org/ontology/PDQ/CDR0000040820 http://purl.bioontology.org/ontology/PDQ/CDR0000039043 http://purl.bioontology.org/ontology/PDQ/CDR0000041732 http://purl.bioontology.org/ontology/PDQ/CDR0000042412 http://purl.bioontology.org/ontology/PDQ/CDR0000344408 http://purl.bioontology.org/ontology/PDQ/CDR0000040076 http://purl.bioontology.org/ontology/PDQ/CDR0000037833 http://purl.bioontology.org/ontology/PDQ/CDR0000043104 http://purl.bioontology.org/ontology/PDQ/CDR0000042371 http://purl.bioontology.org/ontology/PDQ/CDR0000271916 http://purl.bioontology.org/ontology/PDQ/CDR0000041221 http://purl.bioontology.org/ontology/PDQ/CDR0000041721 http://purl.bioontology.org/ontology/PDQ/CDR0000038511 http://purl.bioontology.org/ontology/PDQ/CDR0000042127 http://purl.bioontology.org/ontology/PDQ/CDR0000040900 http://purl.bioontology.org/ontology/PDQ/CDR0000039619 http://purl.bioontology.org/ontology/PDQ/CDR0000041499 http://purl.bioontology.org/ontology/PDQ/CDR0000041811 http://purl.bioontology.org/ontology/PDQ/CDR0000041717 http://purl.bioontology.org/ontology/PDQ/CDR0000042438 http://purl.bioontology.org/ontology/PDQ/CDR0000038041 http://purl.bioontology.org/ontology/PDQ/CDR0000042521 http://purl.bioontology.org/ontology/PDQ/CDR0000038481 http://purl.bioontology.org/ontology/PDQ/CDR0000037933 http://purl.bioontology.org/ontology/PDQ/CDR0000042330 http://purl.bioontology.org/ontology/PDQ/CDR0000040875 http://purl.bioontology.org/ontology/PDQ/CDR0000040963 http://purl.bioontology.org/ontology/PDQ/CDR0000041315 http://purl.bioontology.org/ontology/PDQ/CDR0000042406 http://purl.bioontology.org/ontology/PDQ/CDR0000037772 http://purl.bioontology.org/ontology/PDQ/CDR0000038630 http://purl.bioontology.org/ontology/PDQ/CDR0000043033 http://purl.bioontology.org/ontology/PDQ/CDR0000041128 http://purl.bioontology.org/ontology/PDQ/CDR0000041308 http://purl.bioontology.org/ontology/PDQ/CDR0000041596 http://purl.bioontology.org/ontology/PDQ/CDR0000041007 http://purl.bioontology.org/ontology/PDQ/CDR0000038850 http://purl.bioontology.org/ontology/PDQ/CDR0000041600 http://purl.bioontology.org/ontology/PDQ/CDR0000041942 http://purl.bioontology.org/ontology/PDQ/CDR0000039101 http://purl.bioontology.org/ontology/PDQ/CDR0000041526 http://purl.bioontology.org/ontology/PDQ/CDR0000041261 http://purl.bioontology.org/ontology/PDQ/CDR0000041833 http://purl.bioontology.org/ontology/PDQ/CDR0000039683 http://purl.bioontology.org/ontology/PDQ/CDR0000042393 http://purl.bioontology.org/ontology/PDQ/CDR0000042342 http://purl.bioontology.org/ontology/PDQ/CDR0000041581 http://purl.bioontology.org/ontology/PDQ/CDR0000042635 http://purl.bioontology.org/ontology/PDQ/CDR0000040894 http://purl.bioontology.org/ontology/PDQ/CDR0000043132 http://purl.bioontology.org/ontology/PDQ/CDR0000042350 http://purl.bioontology.org/ontology/PDQ/CDR0000039384 http://purl.bioontology.org/ontology/PDQ/CDR0000040874 http://purl.bioontology.org/ontology/PDQ/CDR0000038306 http://purl.bioontology.org/ontology/PDQ/CDR0000038930 http://purl.bioontology.org/ontology/PDQ/CDR0000040073 http://purl.bioontology.org/ontology/PDQ/CDR0000039036 http://purl.bioontology.org/ontology/PDQ/CDR0000037971 http://purl.bioontology.org/ontology/PDQ/CDR0000041893 http://purl.bioontology.org/ontology/PDQ/CDR0000042004 http://purl.bioontology.org/ontology/PDQ/CDR0000040285 http://purl.bioontology.org/ontology/PDQ/CDR0000039514 http://purl.bioontology.org/ontology/PDQ/CDR0000039664 http://purl.bioontology.org/ontology/PDQ/CDR0000037784 http://purl.bioontology.org/ontology/PDQ/CDR0000350090 http://purl.bioontology.org/ontology/PDQ/CDR0000042413 http://purl.bioontology.org/ontology/PDQ/CDR0000334924 http://purl.bioontology.org/ontology/PDQ/CDR0000039386 http://purl.bioontology.org/ontology/PDQ/CDR0000040655 http://purl.bioontology.org/ontology/PDQ/CDR0000041220 http://purl.bioontology.org/ontology/PDQ/CDR0000040492 http://purl.bioontology.org/ontology/PDQ/CDR0000039045 http://purl.bioontology.org/ontology/PDQ/CDR0000040901 http://purl.bioontology.org/ontology/PDQ/CDR0000039626 http://purl.bioontology.org/ontology/PDQ/CDR0000038602 http://purl.bioontology.org/ontology/PDQ/CDR0000353150 http://purl.bioontology.org/ontology/PDQ/CDR0000038869 http://purl.bioontology.org/ontology/PDQ/CDR0000037822 http://purl.bioontology.org/ontology/PDQ/CDR0000037832 http://purl.bioontology.org/ontology/PDQ/CDR0000043505 http://purl.bioontology.org/ontology/PDQ/CDR0000350368 http://purl.bioontology.org/ontology/PDQ/CDR0000040971 http://purl.bioontology.org/ontology/PDQ/CDR0000269749 http://purl.bioontology.org/ontology/PDQ/CDR0000039333 http://purl.bioontology.org/ontology/PDQ/CDR0000040957 http://purl.bioontology.org/ontology/PDQ/CDR0000038131 http://purl.bioontology.org/ontology/PDQ/CDR0000041465 http://purl.bioontology.org/ontology/PDQ/CDR0000041621 http://purl.bioontology.org/ontology/PDQ/CDR0000038043 http://purl.bioontology.org/ontology/PDQ/CDR0000038482 http://purl.bioontology.org/ontology/PDQ/CDR0000038042 http://purl.bioontology.org/ontology/PDQ/CDR0000038669 http://purl.bioontology.org/ontology/PDQ/CDR0000040398 http://purl.bioontology.org/ontology/PDQ/CDR0000037835 http://purl.bioontology.org/ontology/PDQ/CDR0000041935 http://purl.bioontology.org/ontology/PDQ/CDR0000039520 http://purl.bioontology.org/ontology/PDQ/CDR0000041330 http://purl.bioontology.org/ontology/PDQ/CDR0000041681 http://purl.bioontology.org/ontology/PDQ/CDR0000039400 http://purl.bioontology.org/ontology/PDQ/CDR0000269700 http://purl.bioontology.org/ontology/PDQ/CDR0000042501 http://purl.bioontology.org/ontology/PDQ/CDR0000040873 http://purl.bioontology.org/ontology/PDQ/CDR0000042470 http://purl.bioontology.org/ontology/PDQ/CDR0000393558 http://purl.bioontology.org/ontology/PDQ/CDR0000441004 http://purl.bioontology.org/ontology/PDQ/CDR0000042097 http://purl.bioontology.org/ontology/PDQ/CDR0000407377 http://purl.bioontology.org/ontology/PDQ/CDR0000038309 http://purl.bioontology.org/ontology/PDQ/CDR0000041796 http://purl.bioontology.org/ontology/PDQ/CDR0000040074 http://purl.bioontology.org/ontology/PDQ/CDR0000041329 http://purl.bioontology.org/ontology/PDQ/CDR0000040839 http://purl.bioontology.org/ontology/PDQ/CDR0000038670 http://purl.bioontology.org/ontology/PDQ/CDR0000041084
cui	C1511630 C0723603 C1521935 C1511626 C0733524 C0282120 C0733521 C1521934 C1521933 C0010711 C1511627 C1521931 C1521932 C0591320 C1511628 C1511629 C0591057 C1511631
Date last modified	2017-09-27
definition	An antimetabolite analogue of cytidine with a modified sugar moiety (arabinose instead of ribose). Cytarabine is converted to the triphosphate form within the cell and then competes with cytidine for incorporation into DNA. Because the arabinose sugar sterically hinders the rotation of the molecule within DNA, DNA replication ceases, specifically during the S phase of the cell cycle. This agent also inhibits DNA polymerase, resulting in a decrease in DNA replication and repair. Check for "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C408" active clinical trials using this agent. ("http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C408" NCI Thesaurus)
IND Code	1714
Legacy PDQ ID	158
LT	TRD
NCI ID	C408
notation	CDR0000039015
NSC Code	287459
ORIG STY	Drug/agent
prefLabel	cytarabine
tui	T131 T114 T121

Add comment

Add proposal

Subscribe to notes emails

Delete	Subject	Author	Type	Created
No notes to display

Create mapping

Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/MESH/D003561	MESH	CUI
http://purl.bioontology.org/ontology/MESH/D003561	MESH	CUI
http://purl.bioontology.org/ontology/CSP/2516-7794	CRISP	CUI
http://purl.bioontology.org/ontology/SCTSPA/89265009	SCTSPA	CUI
http://purl.bioontology.org/ontology/RCD/x02Yc	RCD	CUI
http://purl.bioontology.org/ontology/RCD/x02T8	RCD	CUI
http://purl.bioontology.org/ontology/MSHFRE/D003561	MSHFRE	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/387511003	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/SNMI/C-78080	SNMI	CUI
http://purl.bioontology.org/ontology/MESH/D003561	MESH	CUI
http://purl.bioontology.org/ontology/CSP/2516-7794	CRISP	CUI
http://purl.bioontology.org/ontology/SCTSPA/387511003	SCTSPA	CUI
http://purl.bioontology.org/ontology/LNC/MTHU059480	LOINC	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/387511003	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/SNMI/C-78080	SNMI	CUI
http://purl.bioontology.org/ontology/NDDF/002649	NDDF	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000006080	NDFRT	CUI
http://purl.bioontology.org/ontology/RXNORM/3041	RXNORM	CUI
http://purl.bioontology.org/ontology/LNC/LP70367-5	LOINC	CUI
http://purl.bioontology.org/ontology/VANDF/4018080	VANDF	CUI
http://purl.bioontology.org/ontology/MESH/D003561	MESH	CUI
http://purl.bioontology.org/ontology/MSHFRE/D003561	MSHFRE	CUI
http://purl.bioontology.org/ontology/ATC/L01BC01	ATC	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/89265009	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/RCD/h31..	RCD	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000146419	NDFRT	CUI
http://purl.bioontology.org/ontology/MESH/D003561	MESH	CUI
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C408	NCIT	LOOM
http://purl.obolibrary.org/obo/NCIT_C408	BERO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D13.570.065.300	RH-MESH	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00018383	PMAPP-PMO	LOOM
http://purl.obolibrary.org/obo/OMIT_0004847	OMIT	LOOM
http://stirdf.jst.go.jp/id/200907086890392751	IOBC	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D13.570.685.245.453	RH-MESH	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU059480	LOINC	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#3565	OCHV	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387511003	SNOMEDCT	LOOM
http://purl.jp/bio/4/id/200906077177645175	IOBC	LOOM
http://purl.obolibrary.org/obo/MESH_D003561	BERO	LOOM
http://purl.bioontology.org/ontology/SNMI/C-78080	SNMI	LOOM
http://purl.bioontology.org/ontology/NDDF/002649	NDDF	LOOM
http://purl.obolibrary.org/obo/CHEBI_28680	DRON	LOOM
http://purl.obolibrary.org/obo/CHEBI_28680	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_28680	CCONT	LOOM
http://purl.obolibrary.org/obo/CHEBI_28680	HOIP	LOOM
http://purl.obolibrary.org/obo/CHEBI_28680	DINTO	LOOM
http://purl.obolibrary.org/obo/CHEBI_28680	CHEBI	LOOM
http://purl.obolibrary.org/obo/CHEBI_28680	GO-PLUS	LOOM
http://purl.obolibrary.org/obo/CHEBI_28680	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_28680	DDSS	LOOM
http://purl.obolibrary.org/obo/CHEBI_28680	TXPO	LOOM
http://purl.obolibrary.org/obo/CHEBI_28680	BIOMODELS	LOOM
http://purl.obolibrary.org/obo/CHEBI_28680	NIFSTD	LOOM
http://purl.obolibrary.org/obo/CHEBI_28680	ECTO	LOOM
http://purl.obolibrary.org/obo/CHEBI_28680	EFO	LOOM
http://purl.obolibrary.org/obo/CHEBI_28680	OBA	LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000146419	ODAE	LOOM
http://purl.bioontology.org/ontology/RXNORM/3041	RXNORM	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D003561	RH-MESH	LOOM
http://purl.bioontology.org/ontology/LNC/LP70367-5	LOINC	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.383.742.680.245.453	RH-MESH	LOOM
http://purl.bioontology.org/ontology/VANDF/4018080	VANDF	LOOM
http://purl.bioontology.org/ontology/MESH/D003561	MESH	LOOM
http://www.co-ode.org/ontologies/galen#Cytarabine	GALEN	LOOM
https://go.drugbank.com/drugs/DB00987	MDM	LOOM
http://purl.bioontology.org/ontology/ATC/L01BC01	ATC	LOOM
http://www.drugbank.ca/drugs/DB00987	FTC	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0010711	OCHV	LOOM
http://purl.bioontology.org/ontology/RCD/h31..	RCD	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146419	NDFRT	LOOM