loading...| Preferred Name | apoptotic process | |
| Synonyms |
activation of apoptosis apoptosis signaling type I programmed cell death apoptotic program apoptosis apoptosis activator activity caspase-dependent programmed cell death induction of apoptosis signaling (initiator) caspase activity induction of apoptosis by p53 commitment to apoptosis cellular suicide cell suicide apoptotic programmed cell death apoptotic cell death programmed cell death by apoptosis |
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| Definitions |
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. |
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| ID |
http://purl.obolibrary.org/obo/GO_0006915 |
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| database_cross_reference |
Wikipedia:Apoptosis |
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| definition |
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. |
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| ends with | ||
| has part | ||
| has_exact_synonym |
apoptotic programmed cell death apoptotic cell death programmed cell death by apoptosis |
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| has_related_synonym |
apoptosis activator activity caspase-dependent programmed cell death induction of apoptosis signaling (initiator) caspase activity induction of apoptosis by p53 commitment to apoptosis |
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| hasAlternativeId |
GO:0006917 GO:0008632 |
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| hasBroadSynonym |
cellular suicide cell suicide |
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| hasNarrowSynonym |
activation of apoptosis apoptosis signaling type I programmed cell death apoptotic program apoptosis |
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| hasOBONamespace |
biological_process |
|
| id |
GO:0006915 |
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| in taxon | ||
| label |
apoptotic process |
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| notation |
GO:0006915 |
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| only in taxon | ||
| overlaps | ||
| prefLabel |
apoptotic process |
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| RO_0002161 | ||
| starts with | ||
| subClassOf |