loading...| Preferred Name | Idiopathic Thrombocytopenic Purpura | |
| Synonyms |
Werlhof's Syndrome Idiopathic Thrombocytopenic Purpura Werlhof's Disease Autoimmune Thrombocytopenia Idiopathic Thrombocytopenia Idiopathic Purpura Idiopathic Thrombocytopenia Purpura Autoimmune Thrombocytopenic Purpura Immune Thrombocytopenia ITP - idiopathic thrombocytopenic purpura ITP - immune thrombocytopenic purpura Immune Thrombocytopenic Purpura |
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| Definitions |
[GARD Definition]: Idiopathic thrombocytopenic purpura (ITP) is a bleeding disorder characterized by too few platelets in the blood. This is because platelets are being destroyed by the immune system. Symptoms may include bruising, nosebleed or bleeding in the mouth, bleeding into the skin, and abnormally heavy menstruation. With treatment, the chance of remission (a symptom-free period) is good. Rarely, ITP may become a chronic ailment in adults and reappear, even after remission. - this information is from GARD/ORDR/NCATS. [HPO Definition]: The presence of thrombocytopenia in combination with detection of antiplatelet antibodies. [DDD:wouwehand] [MSH Definition]: Thrombocytopenia occurring in the absence of toxic exposure or a disease associated with decreased platelets. It is mediated by immune mechanisms, in most cases IMMUNOGLOBULIN G autoantibodies which attach to platelets and subsequently undergo destruction by macrophages. The disease is seen in acute (affecting children) and chronic (adult) forms. [SNOMEDCT_US Definition]: An autoimmune coagulation disorder characterised by isolated thrombocytopaenia (a platelet count <100,000/microL), in the absence of any underlying disorder that may be associated with thrombocytopenia. [NICHD Definition]: Disorder characterized by abnormally low level of circulating platelets, usually with normal hemoglobin/red blood cell and white blood cell levels, and thought to be secondary to autoimmune destruction. [NCIt Definition]: An autoimmune disorder in which the number of circulating platelets is reduced due to their antibody-mediated destruction. ITP is a diagnosis of exclusion and is heterogeneous in origin. [NCI-GLOSS Definition]: A condition in which platelets (blood cells that cause blood clots to form) are destroyed by the immune system. The low platelet count causes easy bruising and bleeding, which may be seen as purple areas in the skin, mucous membranes, and outer linings of organs. |
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| ID |
http://pat.nichd.nih.gov/maternalconditions/C0920163 |
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| Annotation Terms |
Purpura, Immune Thrombocytopenic Purpuras, Autoimmune Thrombocytopenic Purpura, Thrombocytopenic, Idiopathic [Disease/Finding] Thrombocytopenic Purpuras, Idiopathic Purpura, Autoimmune Thrombocytopenic Autoimmune Thrombocytopenias Autoimmune thrombocytopenia (disorder) Immune Thrombocytopenic Purpuras Purpura, Idiopathic Thrombocytopenic Purpura, Thrombocytopenic, Autoimmune Idiopathic thrombocytopenic purpura (disorder) WERLHOFS DIS PURPURA, THROMBOCYTOPENIC, IDIOPATHIC Thrombocytopenias, Immune Immune Thrombocytopenias Purpuras, Immune Thrombocytopenic WERLHOF DISEASE Thrombocytopenia, Autoimmune Disease, Werlhof WERLHOF DIS Thrombocytopenic Purpura, Immune Autoimmune Thrombocytopenic Purpuras Purpuras, Idiopathic Thrombocytopenic Thrombocytopenias, Autoimmune IDIOPATHIC THROMBOCYTOPENIC PURPURAS Thrombocytopenic Purpura, Idiopathic Thrombocytopenic purpura, autoimmune Thrombocytopenic purpura autoimmune Werlhofs Disease Disease, Werlhof's Thrombocytopenia, Immune Idiopathic thrombocytopenic purpura (ITP) Thrombocytopenic Purpuras, Immune Immune thrombocyt purpra |
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| Definition |
[GARD Definition]: Idiopathic thrombocytopenic purpura (ITP) is a bleeding disorder characterized by too few platelets in the blood. This is because platelets are being destroyed by the immune system. Symptoms may include bruising, nosebleed or bleeding in the mouth, bleeding into the skin, and abnormally heavy menstruation. With treatment, the chance of remission (a symptom-free period) is good. Rarely, ITP may become a chronic ailment in adults and reappear, even after remission. - this information is from GARD/ORDR/NCATS. [HPO Definition]: The presence of thrombocytopenia in combination with detection of antiplatelet antibodies. [DDD:wouwehand] [MSH Definition]: Thrombocytopenia occurring in the absence of toxic exposure or a disease associated with decreased platelets. It is mediated by immune mechanisms, in most cases IMMUNOGLOBULIN G autoantibodies which attach to platelets and subsequently undergo destruction by macrophages. The disease is seen in acute (affecting children) and chronic (adult) forms. [SNOMEDCT_US Definition]: An autoimmune coagulation disorder characterised by isolated thrombocytopaenia (a platelet count <100,000/microL), in the absence of any underlying disorder that may be associated with thrombocytopenia. [NICHD Definition]: Disorder characterized by abnormally low level of circulating platelets, usually with normal hemoglobin/red blood cell and white blood cell levels, and thought to be secondary to autoimmune destruction. [NCIt Definition]: An autoimmune disorder in which the number of circulating platelets is reduced due to their antibody-mediated destruction. ITP is a diagnosis of exclusion and is heterogeneous in origin. [NCI-GLOSS Definition]: A condition in which platelets (blood cells that cause blood clots to form) are destroyed by the immune system. The low platelet count causes easy bruising and bleeding, which may be seen as purple areas in the skin, mucous membranes, and outer linings of organs. |
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| External Source | ||
| Label |
Idiopathic Thrombocytopenic Purpura |
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| notation |
C0920163 |
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| PAT ID |
C0920163 |
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| prefLabel |
Idiopathic Thrombocytopenic Purpura |
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| Sub Class Of | ||
| Synonyms |
Werlhof's Syndrome Idiopathic Thrombocytopenic Purpura Werlhof's Disease Autoimmune Thrombocytopenia Idiopathic Thrombocytopenia Idiopathic Purpura Idiopathic Thrombocytopenia Purpura Autoimmune Thrombocytopenic Purpura Immune Thrombocytopenia ITP - idiopathic thrombocytopenic purpura ITP - immune thrombocytopenic purpura Immune Thrombocytopenic Purpura |