Placental Maternal Health Conditions

Last uploaded: January 13, 2020
Preferred Name

Graves Disease
Synonyms

BASEDOWS DIS

BASEDOW DIS

Graves' disease with exophthalmos

GOITER EXOPHTHALMIC

FLAJANI DISEASE

Goitre exophthalmic

Toxic diffuse goiter with exophthalmos (disorder)

Basedow's disease

GRAVES' DISEASE

Toxic diffuse goiter with exophthalmos

Graves' hyperthyroidism

Autoimmune hyperthyroidism

GOITER, EXOPHTHALMIC

Graves' disease (disorder)

exophthalmic goiter

Morbus Basedow

Grave disease

Disease, Basedow

Disease, Graves'

Hyperthyroidism, Autoimmune

Graves Disease [Disease/Finding]

DISEASE GRAVES'

Exophthalmic Goiters

Goiters, Exophthalmic

Disease, Basedow's

Toxic diffuse goitre with exophthalmos

HYPERTHYROIDISM <GRAVES DISEASE>

Disease, Graves

EXOPHTHALMIC GOITRE

Graves' Disease - hyperthyroidism

Grave's disease

BASEDOW DISEASE

Graves-Basedow disease

Basedows Disease

Grave Krankheit

Graves disease

GRAVES DIS

Definitions

[NCIt Definition]: Hyperthyroidism associated with diffuse hyperplasia of the thyroid gland (goiter), resulting from production of antibodies that are directed against the thyrotropin receptor complex of the follicular epithelial cells. As a result, the thyroid gland enlarges and secrets increased amounts of thyroid hormones. [CSP Definition]: Exophthalmos occurring in association with goiter; hyperthyroidism with protrusion of the eyeballs. [NICHD Definition]: An autoimmune condition characterized by excessive immunoglobulin stimulation of the thyroid gland resulting in hyperthyroidism. [GARD Definition]: Graves' disease is an autoimmune disorder that leads to overactivity of the thyroid gland (hyperthyroidism). It is caused by an abnormal immune system response that causes the thyroid gland to produce too much thyroid hormones. Graves disease is the most common cause of hyperthyroidism and occurs most often in women over age 20. However, the disorder may occur at any age and may affect males as well.  Treatment may include radioiodine therapy, antithyroid drugs, and/or thyroid surgery. - this information is from GARD/ORDR/NCATS. [HPO Definition]: An autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones (a serious metabolic imbalance known as hyperthyroidism and thyrotoxicosis). This is caused by autoantibodies to the TSH-receptor (TSHR-Ab) that activate that TSH-receptor (TSHR), thereby stimulating thyroid hormone synthesis and secretion, and thyroid growth (causing a diffusely enlarged goiter). The resulting state of hyperthyroidism can cause a dramatic constellation of neuropsychological and physical signs and symptoms, which can severely compromise the patients. [HPO:sdoelken] [MSH Definition]: A common form of hyperthyroidism with a diffuse hyperplastic GOITER. It is an autoimmune disorder that produces antibodies against the THYROID STIMULATING HORMONE RECEPTOR. These autoantibodies activate the TSH receptor, thereby stimulating the THYROID GLAND and hypersecretion of THYROID HORMONES. These autoantibodies can also affect the eyes (GRAVES OPHTHALMOPATHY) and the skin (Graves dermopathy).

ID

http://pat.nichd.nih.gov/maternalconditions/C0018213

Definition

[NCIt Definition]: Hyperthyroidism associated with diffuse hyperplasia of the thyroid gland (goiter), resulting from production of antibodies that are directed against the thyrotropin receptor complex of the follicular epithelial cells. As a result, the thyroid gland enlarges and secrets increased amounts of thyroid hormones.

[CSP Definition]: Exophthalmos occurring in association with goiter; hyperthyroidism with protrusion of the eyeballs.

[NICHD Definition]: An autoimmune condition characterized by excessive immunoglobulin stimulation of the thyroid gland resulting in hyperthyroidism.

[GARD Definition]: Graves' disease is an autoimmune disorder that leads to overactivity of the thyroid gland (hyperthyroidism). It is caused by an abnormal immune system response that causes the thyroid gland to produce too much thyroid hormones. Graves disease is the most common cause of hyperthyroidism and occurs most often in women over age 20. However, the disorder may occur at any age and may affect males as well.  Treatment may include radioiodine therapy, antithyroid drugs, and/or thyroid surgery. - this information is from GARD/ORDR/NCATS.

[HPO Definition]: An autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones (a serious metabolic imbalance known as hyperthyroidism and thyrotoxicosis). This is caused by autoantibodies to the TSH-receptor (TSHR-Ab) that activate that TSH-receptor (TSHR), thereby stimulating thyroid hormone synthesis and secretion, and thyroid growth (causing a diffusely enlarged goiter). The resulting state of hyperthyroidism can cause a dramatic constellation of neuropsychological and physical signs and symptoms, which can severely compromise the patients. [HPO:sdoelken]

[MSH Definition]: A common form of hyperthyroidism with a diffuse hyperplastic GOITER. It is an autoimmune disorder that produces antibodies against the THYROID STIMULATING HORMONE RECEPTOR. These autoantibodies activate the TSH receptor, thereby stimulating the THYROID GLAND and hypersecretion of THYROID HORMONES. These autoantibodies can also affect the eyes (GRAVES OPHTHALMOPATHY) and the skin (Graves dermopathy).

External Source

https://ncit-stage.nci.nih.gov/ncitbrowser/pages/concept_details.jsf?dictionary=NCI%20Thesaurus&code=C3071

Label

Graves Disease

notation

C0018213

PAT ID

C0018213

prefLabel

Graves Disease

Sub Class Of

http://pat.nichd.nih.gov/maternalconditions/C0020550

Synonyms

BASEDOWS DIS

BASEDOW DIS

Graves' disease with exophthalmos

GOITER EXOPHTHALMIC

FLAJANI DISEASE

Goitre exophthalmic

Toxic diffuse goiter with exophthalmos (disorder)

Basedow's disease

GRAVES' DISEASE

Toxic diffuse goiter with exophthalmos

Graves' hyperthyroidism

Autoimmune hyperthyroidism

GOITER, EXOPHTHALMIC

Graves' disease (disorder)

exophthalmic goiter

Morbus Basedow

Grave disease

Disease, Basedow

Disease, Graves'

Hyperthyroidism, Autoimmune

Graves Disease [Disease/Finding]

DISEASE GRAVES'

Exophthalmic Goiters

Goiters, Exophthalmic

Disease, Basedow's

Toxic diffuse goitre with exophthalmos

HYPERTHYROIDISM <GRAVES DISEASE>

Disease, Graves

EXOPHTHALMIC GOITRE

Graves' Disease - hyperthyroidism

Grave's disease

BASEDOW DISEASE

Graves-Basedow disease

Basedows Disease

Grave Krankheit

Graves disease

GRAVES DIS

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Delete Mapping To Ontology Source
http://www.ebi.ac.uk/efo/EFO_0004237 EFO LOOM
http://www.phoc.org.cn/pmo/class/PMO_00037048 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/MEDLINEPLUS/C0018213 MEDLINEPLUS LOOM
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http://www.ebi.ac.uk/efo/EFO_0004237 EFO LOOM
http://purl.bioontology.org/ontology/MESH/D006111 MESH LOOM
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http://purl.bioontology.org/ontology/OMIM/275000 OMIM LOOM
http://purl.obolibrary.org/obo/HP_0100647 HP LOOM
http://purl.obolibrary.org/obo/HP_0100647 UPHENO LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Graves_Disease CSEO LOOM
http://purl.obolibrary.org/obo/MONDO_0005364 MONDO LOOM
http://purl.obolibrary.org/obo/MONDO_0005364 DOVES LOOM
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http://purl.bioontology.org/ontology/SNOMEDCT/353295004 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/RCD/X40OI RCD LOOM
rgo:18583 GAMUTS LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C20.111.555 RH-MESH LOOM
http://localhost/plosthes.2017-1#4408 PLOSTHES LOOM
http://www.owl-ontologies.com/NPOntology.owl#DOID_12361 NATPRO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C19.874.283.605 RH-MESH LOOM
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